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Matt Botvinick: Neuroscience, Psychology, and AI at DeepMind

第106期2020-07-03English

嘉宾:Matt Botvinick

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§01Transcript · 00:00–09:34

00:00The following is a conversation with Matt Botmanick,

00:03Director of Neuroscience Research at DeepMind.

00:06He's a brilliant, cross-disciplinary mind

00:09navigating effortlessly between cognitive psychology,

00:12computational neuroscience, and artificial intelligence.

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03:24And now, here's my conversation with Matt Botvinick.

03:28How much of the human brain do you think we understand?

03:32- I think we're at a weird moment

03:36in the history of neuroscience in the sense that

03:40I feel like we understand a lot about the brain

03:47at a very high level,

03:49but a very coarse level.

03:52- When you say high level, what are you thinking?

03:54Are you thinking functional?

03:55Are you thinking structurally?

03:57- So in other words, what is the brain for?

04:00You know, what kinds of computation does the brain do?

04:03What kinds of behaviors would we have to explain

04:10if we were gonna look down at the mechanistic level?

04:15And at that level, I feel like we understand

04:18much, much more about the brain than we did

04:20when I was in high school.

04:22But it's almost like we're seeing it through a fog.

04:25It's only at a very coarse level.

04:26We don't really understand what the neuronal mechanisms are

04:30that underlie these computations.

04:32We've gotten better at saying,

04:34what are the functions that the brain is computing

04:36that we would have to understand

04:38if we were gonna get down to the neuronal level?

04:40And at the other end of the spectrum,

04:45in the last few years, incredible progress has been made

04:49in terms of technologies that allow us to see,

04:54actually literally see in some cases,

04:57what's going on at the single unit level,

05:01even the dendritic level.

05:02And then there's this yawning gap in between.

05:05- Well, that's interesting.

05:06So at the high level,

05:07so that's almost a cognitive science level.

05:09And then at the neuronal level,

05:11that's neurobiology and neuroscience,

05:14just studying single neurons,

05:16the synaptic connections and all the dopamine,

05:19all the kind of neurotransmitters.

05:21- One blanket statement I should probably make is that,

05:24as I've gotten older,

05:27I have become more and more reluctant

05:30to make a distinction between psychology and neuroscience.

05:33To me, the point of neuroscience

05:37is to study what the brain is for.

05:41If you're a nephrologist

05:44and you wanna learn about the kidney,

05:46you start by saying, what is this thing for?

05:49Well, it seems to be for taking blood on one side

05:54that has metabolites in it that shouldn't be there,

06:00sucking them out of the blood

06:03while leaving the good stuff behind,

06:05and then excreting that in the form of urine.

06:07That's what the kidney is for, it's like obvious.

06:10So the rest of the work is deciding how it does that.

06:13And this, it seems to me,

06:14is the right approach to take to the brain.

06:17You say, well, what is the brain for?

06:19The brain, as far as I can tell, is for producing behavior.

06:22It's for going from perceptual inputs to behavioral outputs,

06:26and the behavioral outputs should be adaptive.

06:30So that's what psychology is about.

06:33It's about understanding the structure of that function.

06:35And then the rest of neuroscience is about figuring out

06:38how those operations are actually carried out

06:41at a mechanistic level.

06:44- That's really interesting, but,

06:45so unlike the kidney, the brain,

06:49the gap between the electrical signal and behavior,

06:53so you truly see neuroscience as the science

06:59that touches behavior, how the brain generates behavior,

07:03or how the brain converts raw visual information

07:07into understanding.

07:09Like, you basically see cognitive science,

07:12psychology, and neuroscience as all one science.

07:15- Yeah.

07:16- Is that-- - It's a personal statement.

07:19I don't mean to-- - Is that a hopeful,

07:20is that a hopeful or a realistic statement?

07:22So certainly you will be correct in your feeling

07:26in some number of years, but that number of years

07:29could be 200, 300 years from now.

07:31- Oh, well, there's a--

07:33- Is that aspirational, or is that pragmatic engineering

07:37feeling that you have?

07:39- It's both in the sense that this is what I hope

07:44and expect will bear fruit over the coming decades,

07:51but it's also pragmatic in the sense that I'm not sure

07:57what we're doing in either psychology or neuroscience

08:02if that's not the framing.

08:04I don't know what it means to understand the brain

08:09if part of the enterprise is not about understanding

08:14the behavior that's being produced.

08:20- I mean, yeah, but I would compare it to maybe

08:24astronomers looking at the movement of the planets

08:27and the stars without any interest

08:30of the underlying physics, right?

08:32And I would argue that at least in the early days,

08:35there's some value to just tracing the movement

08:37of the planets and the stars without thinking

08:41about the physics too much because it's such a big leap

08:44to start thinking about the physics

08:45before you even understand even the basic

08:48structural elements of--

08:49- Oh, I agree with that, I agree.

08:51- But you're saying in the end,

08:52the goal should be to deeply understand.

08:54- Well, right, and I think, so I thought about this

08:58a lot when I was in grad school 'cause a lot of what

08:59I studied in grad school was psychology,

09:01and I found myself a little bit confused

09:06about what it meant to, it seems like what we were talking

09:10about a lot of the time were virtual causal mechanisms.

09:14Like, oh, well, attentional selection then selects

09:19some object in the environment and that is then passed on

09:24to the motor, information about that is passed on

09:26to the motor system, but these are virtual mechanisms.

09:29These are, they're metaphors, there's no reduction

09:34going on in that conversation to some physical mechanism

§02Transcript · 09:39–20:02

09:39that, which is really what it would take

09:43to fully understand how behavior is rising.

09:47But the causal mechanisms are definitely neurons

09:50interacting, I'm willing to say that

09:51at this point in history.

09:53So in psychology, at least for me personally,

09:56there was this strange insecurity about trafficking

10:00in these metaphors, which were supposed to explain

10:04the function of the mind.

10:05If you can't ground them in physical mechanisms,

10:09then what is the explanatory validity of these explanations?

10:14And I managed to soothe my own nerves by thinking

10:24about the history of genetics research.

10:29So I'm very far from being an expert

10:32on the history of this field, but I know enough to say

10:36that Mendelian genetics preceded Watson and Crick.

10:41And so there was a significant period of time

10:45during which people were productively investigating

10:52the structure of inheritance using what was essentially

10:56a metaphor, the notion of a gene.

10:58Oh, genes do this and genes do that,

11:00but where are the genes?

11:02They're sort of an explanatory thing that we made up

11:06and we ascribed to them these causal properties.

11:08Oh, there's a dominant, there's a recessive,

11:10and then they recombine it.

11:12And then later, there was a kind of blank there

11:17that was filled in with a physical mechanism.

11:21That connection was made.

11:22But it was worth having that metaphor

11:26because that gave us a good sense

11:29of what kind of causal mechanism we were looking for.

11:34- And the fundamental metaphor of cognition,

11:38you said, is the interaction of neurons.

11:40What is the metaphor?

11:42- No, no, the metaphors we use in cognitive psychology

11:47are things like attention, the way that memory works.

11:52I retrieve something from memory.

11:59A memory retrieval occurs.

12:01What is that?

12:02That's not a physical mechanism

12:06that I can examine in its own right.

12:08But it's still worth having, that metaphorical level.

12:13- Yeah, I misunderstood, actually.

12:15So the higher level abstractions

12:17is the metaphor that's most useful.

12:19- Yes.

12:20- But what about, so how does that connect

12:24to the idea that that arises from interaction of neurons?

12:29- Well--

12:33- Is the interaction of neurons also not a metaphor to you?

12:38Or is it literally, like, that's no longer a metaphor.

12:42That's already the lowest level of abstractions

12:46that could actually be directly studied.

12:48- Well, I'm hesitating because I think

12:53what I wanna say could end up being controversial.

12:56So what I wanna say is, yes, the interactions of neurons,

13:01that's not metaphorical, that's a physical fact.

13:04That's where the causal interactions actually occur.

13:08Now, I suppose you could say, well,

13:10even that is metaphorical relative

13:12to the quantum events that underlie,

13:14you know, I don't wanna go down that rabbit hole.

13:17- It's always turtles on top of turtles, yeah.

13:18There's turtles all the way down.

13:20- There is a reduction that you can do.

13:22You can say these psychological phenomena

13:24can be explained through a very different

13:28kind of causal mechanism,

13:29which has to do with neurotransmitter release.

13:31And so what we're really trying to do

13:33in neuroscience writ large, as I say,

13:37which for me includes psychology,

13:39is to take these psychological phenomena

13:44and map them onto neural events.

13:48I think remaining forever at the level of description

13:54that is natural for psychology,

14:00for me personally, would be disappointing.

14:02I wanna understand how mental activity

14:05arises from neural activity.

14:10But the converse is also true.

14:12Studying neural activity without any sense

14:15of what you're trying to explain,

14:18to me feels like at best,

14:23groping around at random.

14:27- Now, you've kind of talked about this

14:29bridging of the gap between psychology and neuroscience,

14:32but do you think it's possible,

14:33like my love is,

14:36like I fell in love with psychology

14:38and psychiatry in general with Freud

14:40when I was really young,

14:41and I hope to understand the mind.

14:43And for me, understanding the mind,

14:45at least at a young age,

14:47before I discovered AI and even neuroscience,

14:49is psychology.

14:52And do you think it's possible to understand the mind

14:55without getting into all the messy details of neuroscience?

14:59Like you kind of mentioned,

15:01to you it's appealing to try to understand the mechanisms

15:05at the lowest level, but do you think that's needed,

15:07that's required, to understand how the mind works?

15:10- That's an important part of the whole picture,

15:14but I would be the last person on Earth

15:18to suggest that that reality

15:23renders psychology in its own right unproductive.

15:27I trained as a psychologist.

15:31I am fond of saying that I have learned much more

15:34from psychology than I have from neuroscience.

15:38To me, psychology is a hugely important discipline.

15:43And one thing that warms my heart is that

15:47ways of investigating behavior

15:54that have been native to cognitive psychology

15:57since its dawn in the '60s

16:01are starting to become,

16:04they're starting to become interesting to AI researchers

16:07for a variety of reasons.

16:09And that's been exciting for me to see.

16:11- Can you maybe talk a little bit about what you see as

16:15beautiful aspects of psychology,

16:19maybe limiting aspects of psychology?

16:21I mean, maybe just start it off as a science, as a field.

16:25- To me, it was when I understood what psychology is,

16:29analytical psychology,

16:30like the way it's actually carried out,

16:32it was really disappointing to see two aspects.

16:36One is how small the N is,

16:39how small the number of subject is in the studies.

16:43And two, it was disappointing to see

16:45how controlled the entire, how much it was in the lab.

16:49It wasn't studying humans in the wild.

16:52There was no mechanism for studying humans in the wild.

16:54So that's where I became a little bit disillusioned

16:57to psychology.

16:59And then the modern world of the internet

17:01is so exciting to me,

17:02the Twitter data or YouTube data,

17:05data of human behavior on the internet becomes exciting

17:08because the N grows and then in the wild grows.

17:11But that's just my narrow sense.

17:13Like, do you have a optimistic or pessimistic,

17:16cynical view of psychology?

17:18How do you see the field broadly?

17:19- When I was in graduate school,

17:22it was early enough that there was still a thrill

17:27in seeing that there were ways of doing,

17:32there were ways of doing experimental science

17:35that provided insight to the structure of the mind.

17:40One thing that impressed me most

17:42when I was at that stage in my education

17:44was neuropsychology,

17:46looking at, looking at the,

17:48analyzing the behavior of populations

17:51who had brain damage of different kinds

17:55and trying to understand what the specific deficits were

18:00that arose from a lesion in a particular part of the brain.

18:06And the kind of experimentation that was done

18:08and that's still being done to get answers in that context

18:13was so creative and it was so deliberate.

18:18It was good science.

18:21An experiment answered one question but raised another

18:24and somebody would do an experiment

18:25that answered that question.

18:26And you really felt like you were narrowing in on

18:29some kind of approximate understanding

18:31of what this part of the brain was for.

18:34- Do you have an example from memory

18:36of what kind of aspects of the mind

18:39could be studied in this kind of way?

18:41- Oh, sure.

18:42I mean, the very detailed neuropsychological studies

18:45of language, language function,

18:49looking at production and reception

18:52and the relationship between, you know,

18:54visual function, you know,

18:57reading and auditory and semantic.

19:00And there were these, and still are,

19:02these beautiful models that came out

19:04of that kind of research that really made you feel

19:07like you understood something

19:08that you hadn't understood before

19:10about how, you know,

19:12language processing is organized in the brain.

19:15But having said all that,

19:17you know, I think, you know,

19:22I think you are, I mean, I agree with you

19:25that the cost of doing highly controlled experiments

19:30is that you, by construction, miss out on the richness

19:35and complexity of the real world.

19:39One thing that, so I was drawn into science

19:42by what in those days was called connectionism,

19:44which is of course the, you know,

19:46what we now call deep learning.

19:48And at that point in history,

19:50neural networks were primarily being used

19:54in order to model human cognition.

19:56They weren't yet really useful for industrial applications.

20:00- So you always found neural networks

20:02in biological form beautiful.

§03Transcript · 20:04–30:15

20:04- Oh, neural networks were very concretely the thing

20:07that drew me into science.

20:09I was handed, are you familiar with the PDP books

20:13from the '80s?

20:14So when I was in, I went to medical school

20:16before I went into science.

20:18And-- - Really?

20:19- Yeah. - Interesting.

20:20Wow. - I also did a graduate degree

20:23in art history, so I kind of explore it.

20:26- Well, art history, I understand.

20:28That's just a curious, creative mind.

20:31But medical school, with the dream of what?

20:33If we take that slight tangent,

20:35did you want to be a surgeon?

20:39- I actually was quite interested in surgery.

20:41I was interested in surgery and psychiatry.

20:44And I thought, I must be the only person

20:47on the planet who was torn between those two fields.

20:52And I said exactly that to my advisor in medical school,

20:56who turned out, I found out later,

20:59to be a famous psychoanalyst.

21:01And he said to me, "No, no, it's actually not so uncommon

21:05"to be interested in surgery and psychiatry."

21:07And he conjectured that the reason

21:10that people develop these two interests

21:12is that both fields are about going beneath the surface

21:15and kind of getting into the kind of secret.

21:19I mean, maybe you understand this

21:20as someone who was interested in psychoanalysis

21:22at a younger stage.

21:23There's sort of a, there's a cliche phrase

21:26that people use now on NPR,

21:28the secret life of blankety-blank, right?

21:31And that was part of the thrill of surgery,

21:33was seeing the secret activity

21:38that's inside everybody's abdomen and thorax.

21:40- That's a very poetic way to connect it to disciplines

21:43that are very, practically speaking,

21:45different from each other, I think.

21:46- That's for sure, that's for sure, yes.

21:48- So how did we get onto medical school?

21:52- So I was in medical school

21:53and I was doing a psychiatry rotation

21:57and my kind of advisor in that rotation

22:01asked me what I was interested in.

22:04And I said, "Well, maybe psychiatry."

22:07He said, "Why?"

22:09And I said, "Well, I've always been interested

22:11"in how the brain works.

22:13"I'm pretty sure that nobody's doing scientific research

22:16"that addresses my interests, which are,"

22:20I didn't have a word for it then,

22:21but I would have said, "about cognition."

22:25And he said, "Well, you know, I'm not sure that's true.

22:27"You might be interested in these books."

22:29And he pulled down the PDB books from his shelf

22:32and they were still shrink-wrapped.

22:34He hadn't read them, but he handed them to me.

22:36He said, "You feel free to borrow these."

22:38And that was, you know, I went back to my dorm room

22:41and I just, you know, read them cover to cover.

22:43- What's PDP?

22:44- Parallel Distributed Processing,

22:46which was one of the original names for deep learning.

22:50- And so, I apologize for the romanticized question,

22:55but what idea in the space of neuroscience,

22:58in the space of the human brain,

22:59is to you the most beautiful, mysterious, surprising?

23:03- What had always fascinated me,

23:07even when I was a pretty young kid, I think,

23:12was the paradox that lies in the fact

23:17that the brain is so mysterious and seems so distant.

23:26But at the same time,

23:32it's responsible for the full transparency

23:37of everyday life.

23:39The brain is literally what makes everything obvious

23:41and familiar.

23:42And there's always one in the room with you.

23:47- Yeah.

23:48- I used to teach, when I taught at Princeton,

23:50I used to teach a cognitive neuroscience course.

23:53And the very last thing I would say to the students was,

23:56you know, when people think of scientists

24:01as scientific inspiration, the metaphor is often,

24:05well, look to the stars, you know?

24:08The stars will inspire you to wonder at the universe

24:11and think about your place in it and how things work.

24:16And I'm all for looking at the stars,

24:18but I've always been much more inspired.

24:21And my sense of wonder comes from the,

24:25not from the distant, mysterious stars,

24:28but from the extremely intimately close brain.

24:33- Yeah.

24:35- There's something just endlessly fascinating

24:38to me about that.

24:40- Like Jessica said, the one that's close and yet distant,

24:45in terms of our understanding of it,

24:47do you, are you also captivated by the fact

24:52that this very conversation is happening

24:55because two brains are communicating?

24:57- Yes, exactly.

24:58- I guess what I mean is the subjective nature

25:03of the experience, if we can take a small tangent

25:06into the mystical of it, the consciousness,

25:10or when you're saying you're captivated

25:13by the idea of the brain, are you talking

25:15about specifically the mechanism of cognition?

25:18Or are you also just, like, at least for me,

25:23it's almost like paralyzing the beauty and the mystery

25:26of the fact that it creates the entirety of the experience,

25:29not just the reasoning capability, but the experience?

25:32- Well, I definitely resonate with that latter thought.

25:37And I often find discussions of artificial intelligence

25:43to be disappointingly narrow.

25:49Speaking as someone who has always had an interest in art,

25:55- Right, I was just gonna go there,

25:57'cause it sounds like somebody who has an interest in art.

26:00- Yeah, I mean, there are many layers

26:04to full bore human experience.

26:08And in some ways, it's not enough to say,

26:11"Oh, well, don't worry, we're talking about cognition,

26:14but we'll add emotion."

26:16- Yeah.

26:17- There's an incredible scope to what humans go through

26:24in every moment.

26:25And yes, so that's part of what fascinates me,

26:33is that our brains are producing that,

26:37but at the same time, it's so mysterious to us, how?

26:43- Yeah.

26:44- Like, we literally, our brains are literally

26:48in our heads producing this experience.

26:50- Producing the experience.

26:52- And yet, it's so mysterious to us,

26:55and the scientific challenge of getting at

26:57the actual explanation for that is so overwhelming.

27:02That's just, I don't know.

27:05Certain people have fixations on particular questions,

27:08and that's always, that's just always been mine.

27:11- Yeah, I would say the poetry of that is fascinating.

27:14And I'm really interested in natural language as well.

27:16And when you look at artificial intelligence community,

27:19it always saddens me how much,

27:23when you try to create a benchmark for the community

27:26to gather around, how much of the magic of language

27:30is lost when you create that benchmark.

27:33That there's something, we talk about experience,

27:35the music, the language, the wit,

27:38the something that makes a rich experience,

27:41something that would be required to pass

27:43the spirit of the Turing test is lost in these benchmarks.

27:47And I wonder how to get it back in,

27:50'cause it's very difficult.

27:51The moment you try to do real good rigorous science,

27:55you lose some of that magic.

27:57When you try to study cognition

28:00in a rigorous scientific way,

28:01it feels like you're losing some of the magic.

28:03- Mm-hmm, mm-hmm.

28:04- The seeing cognition in a mechanistic way

28:07that AI, at this stage in our history, okay.

28:10- Well, I agree with you, but at the same time,

28:13one thing that I found really exciting

28:18about that first wave of deep learning models in cognition

28:23was the fact that the people who were building these models

28:28were focused on the richness and complexity

28:33of human cognition.

28:34So an early debate in cognitive science,

28:39which I sort of witnessed as a grad student,

28:41was about something that sounds very dry,

28:44which is the formation of the past tense.

28:47But there were these two camps.

28:49One said, well, the mind encodes certain rules,

28:54and it also has a list of exceptions,

28:57because of course, the rule is add E-D,

29:00but that's not always what you do,

29:01so you have to have a list of exceptions.

29:03And then there were the connectionists

29:07who evolved into the deep learning people,

29:10who said, well, if you look carefully at the data,

29:13if you actually look at corpora, like language corpora,

29:18it turns out to be very rich,

29:20because yes, there are most verbs,

29:25and you just tack on E-D, and then there are exceptions,

29:28but there are rules that,

29:32the exceptions aren't just random.

29:36There are certain clues to which verbs should be exceptional,

29:41and then there are exceptions to the exceptions,

29:44and there was a word that was kind of deployed

29:47in order to capture this, which was quasi-regular.

29:51In other words, there are rules, but it's messy,

29:54and there's structure even among the exceptions,

29:58and it would be, yeah, you could try to write down

30:03the structure in some sort of closed form,

30:04but really, the right way to understand

30:07how the brain is handling all this,

30:09and by the way, producing all of this,

30:11is to build a deep neural network

30:14and train it on this data

30:15and see how it ends up representing all of this richness.

§04Transcript · 30:18–39:55

30:18So the way that deep learning

30:21was deployed in cognitive psychology

30:23was that was the spirit of it.

30:25It was about that richness,

30:28and that's something that I always found very compelling.

30:31Still do.

30:33- Is there something especially interesting

30:36and profound to you in terms of our current deep learning

30:39neural network, artificial neural network approaches,

30:42and whatever we do understand

30:46about the biological neural networks in our brain?

30:48There's quite a few differences.

30:52Are some of them to you either interesting

30:55or perhaps profound in terms of the gap

31:02we might want to try to close

31:04in trying to create a human-level intelligence?

31:07- What I would say here is something

31:08that a lot of people are saying,

31:10which is that one seeming limitation

31:15of the systems that we're building now

31:18is that they lack the kind of flexibility,

31:21the readiness to sort of turn on a dime

31:25when the context calls for it

31:28that is so characteristic of human behavior.

31:32So--

31:33- Is that connected to you to the,

31:34like which aspect of the neural networks in our brain

31:37is that connected to?

31:39Is that closer to the cognitive science level of...

31:42Now again, see, like my natural inclination

31:47is to separate into three disciplines

31:49of neuroscience, cognitive science, and psychology,

31:54and you've already kind of shut that down

31:56by saying you're kind of seeing them as separate,

31:58but just to look at those layers, I guess,

32:02where is there something about the lowest layer

32:05of the way the neurons interact

32:09that is profound to you in terms of its difference

32:13to the artificial neural networks?

32:15Or is all the key differences

32:17at a higher level of abstraction?

32:19- One thing I often think about is that,

32:24if you take an introductory computer science course

32:27and they are introducing you

32:28to the notion of Turing machines,

32:31one way of articulating what the significance

32:36of a Turing machine is, is that it's a machine emulator.

32:41It can emulate any other machine.

32:45And that to me,

32:52that way of looking at a Turing machine

32:54really sticks with me.

32:57I think of humans as maybe sharing

33:01in some of that character.

33:04We're capacity limited, we're not Turing machines,

33:06obviously, but we have the ability to adapt behaviors

33:10that are very much unlike anything we've done before,

33:15but there's some basic mechanism

33:17that's implemented in our brain

33:18that allows us to run software.

33:22- But just on that point, you mentioned Turing machine,

33:24but nevertheless, it's fundamentally our brains

33:27are just computational devices in your view?

33:29Is that what you're getting at?

33:32It was a little bit unclear to this line you drew.

33:35Is there any magic in there

33:37or is it just basic computation?

33:40- I'm happy to think of it as just basic computation,

33:43but mind you, I won't be satisfied

33:46until somebody explains to me

33:47what the basic computations are

33:49that are leading to the full richness of human cognition.

33:53- Yes.

33:54- I mean, it's not gonna be enough for me

33:56to understand what the computations are

33:58that allow people to do arithmetic or play chess.

34:02I want the whole thing.

34:06- And a small tangent,

34:07because you kind of mentioned coronavirus,

34:10there's group behavior.

34:12- Oh, sure.

34:13- Is there something interesting

34:14to your search of understanding the human mind

34:18where behavior of large groups

34:21or just behavior of groups is interesting?

34:24Seeing that as a collective mind,

34:25as a collective intelligence,

34:27perhaps seeing the groups of people

34:28as a single intelligent organisms,

34:31especially looking at the reinforcement learning work

34:34you've done recently.

34:35- Well, yeah, I can't, I mean,

34:37I have the honor of working

34:41with a lot of incredibly smart people

34:43and I wouldn't wanna take any credit

34:46for leading the way on the multi-agent work

34:48that's come out of my group or DeepMind lately,

34:51but I do find it fascinating.

34:53And I mean, I think there,

34:57I think it can't be debated.

35:01The human behavior arises within communities.

35:06That just seems to me self-evident.

35:08- But to me, it is self-evident,

35:11but that seems to be a profound aspects

35:14of something that created.

35:16That was like, if you look at like 2001 Space Odyssey

35:19when the monkeys touched the,

35:21like that's the magical moment.

35:23I think Yuval Harari argues that the ability

35:26of our large numbers of humans to hold an idea,

35:30to converge towards idea together,

35:31like you said, shaking hands versus bumping elbows,

35:34somehow converge like without even like,

35:38like without being in a room altogether,

35:40just kind of this like distributed convergence

35:43towards an idea over a particular period of time

35:46seems to be fundamental to just every aspect

35:51of our cognition of our intelligence,

35:53because humans, we'll talk about reward,

35:56but it seems like we don't really have

35:58a clear objective function under which we operate,

36:01but we all kind of converge towards one somehow.

36:04And that to me has always been a mystery

36:06that I think is somehow productive

36:09for also understanding AI systems.

36:13But I guess that's the next step.

36:16The first step is try to understand the mind.

36:18- Well, I don't know.

36:19I mean, I think there's something to the argument

36:22that that kind of bottom,

36:25like strictly bottom-up approach is wrong-headed.

36:29In other words, there are basic phenomena that,

36:34basic aspects of human intelligence

36:36that can only be understood in the context of groups.

36:41I'm perfectly open to that.

36:44I've never been particularly convinced by the notion

36:48that we should consider intelligence to adhere

36:53at the level of communities.

36:55I don't know why.

36:57I just, I'm sort of stuck on the notion

36:58that the basic unit that we want to understand

37:01is individual humans.

37:02And if we have to understand that

37:05in the context of other humans, fine.

37:07But for me, intelligence is just,

37:11I'm stubbornly, I stubbornly define it as something

37:14that is an aspect of an individual human.

37:18That's just my, I don't know if that's my take.

37:20- I'm with you, but that could be the reductionist dream

37:22of a scientist because you can understand a single human.

37:26It also is very possible that intelligence can only arise

37:30when there's multiple intelligences.

37:32When there's multiple sort of, it's a sad thing,

37:37if that's true, because it's very difficult to study.

37:39But if it's just one human,

37:42that one human would not be homo sapien,

37:44would not become that intelligent.

37:46That's a real, that's a possibility.

37:48- I'm with you.

37:49One thing I will say along these lines

37:52is that I think,

37:58I think a serious effort to understand human intelligence

38:03and maybe to build a human-like intelligence

38:09needs to pay just as much attention

38:11to the structure of the environment

38:14as to the structure of the, you know,

38:17the cognizing system, whether it's a brain or an AI system.

38:22That's one thing I took away actually from my early studies

38:26with the pioneers of neural network research,

38:29people like Jay McClelland and John Cohen.

38:32The structure of cognition is really,

38:38it's only partly a function of the, you know,

38:42the architecture of the brain

38:44and the learning algorithms that it implements.

38:46What it's really a function,

38:48what really shapes it is the interaction of those things

38:51with the structure of the world

38:54in which those things are embedded, right?

38:56- And that's especially important for,

38:58that's made most clear in reinforcement learning

39:00where a simulated environment is,

39:03you can only learn as much as you can simulate,

39:05and that's what made, what DeepMind made very clear

39:09with the other aspect of the environment,

39:11which is the self-play mechanism

39:13of the other agent of the competitive behavior,

39:16which the other agent becomes the environment essentially.

39:19And that's, I mean, one of the most exciting ideas in AI

39:24is the self-play mechanism

39:25that's able to learn successfully.

39:27So there you go.

39:28There's a thing where competition is essential for learning,

39:33at least in that context.

39:35So if we can step back into another sort of beautiful world,

39:37which is the actual mechanics,

39:42the dirty mess of it, of the human brain,

39:44is there something for people who might not know,

39:48is there something you can comment on

39:51or describe the key parts of the brain

39:53that are important for intelligence,

39:55or just in general, what are the different parts

§05Transcript · 39:58–50:32

39:58of the brain that you're curious about,

39:59that you've studied, and that are just good to know about

40:03when you're thinking about cognition?

40:06- Well, my area of expertise, if I have one,

40:11is prefrontal cortex.

40:14So-- - What's that?

40:16(laughing)

40:17Where do we-- - It depends on who you ask.

40:19The technical definition is anatomical.

40:24There are parts of your brain

40:30that are responsible for motor behavior,

40:32and they're very easy to identify.

40:34And the region of your cerebral cortex,

40:40the sort of outer crust of your brain

40:43that lies in front of those

40:46is defined as the prefrontal cortex.

40:49- And when you say anatomical, sorry to interrupt,

40:51so that's referring to sort of the geographic region,

40:56as opposed to some kind of functional definition.

41:00- Exactly, so this is kind of the coward's way out.

41:04I'm telling you what the prefrontal cortex is

41:06just in terms of what part of the real estate it occupies.

41:09- The thing in the front of the brain.

41:10- Yeah, exactly.

41:11And in fact, the early history of neuroscientific research

41:16of neuroscientific investigation

41:20of what this front part of the brain does

41:23is sort of funny to read because

41:26it was really World War I that started people

41:33down this road of trying to figure out

41:35what different parts of the brain, the human brain do

41:38in the sense that there were a lot of people

41:41with brain damage who came back from the war

41:43with brain damage.

41:44And that provided, as tragic as that was,

41:47it provided an opportunity for scientists

41:49to try to identify the functions of different brain regions.

41:53And that was actually incredibly productive.

41:56But one of the frustrations that neuropsychologists faced

41:59was they couldn't really identify exactly

42:02what the deficit was that arose from damage

42:05to these most kind of frontal parts of the brain.

42:08It was just a very difficult thing to pin down.

42:13There were a couple of neuropsychologists

42:16who identified through a large amount

42:20of clinical experience and close observation,

42:22they started to put their finger on a syndrome

42:26that was associated with frontal damage.

42:27Actually, one of them was a Russian neuropsychologist

42:30named Luria, who students of cognitive psychology still read.

42:35And what he started to figure out

42:40was that the frontal cortex was somehow involved

42:43in flexibility, in guiding behaviors

42:48that required someone to override a habit

42:54or to do something unusual,

42:57or to change what they were doing in a very flexible way

43:01from one moment to another.

43:02- So focused on like new experiences.

43:05And so the way your brain processes

43:08and acts in new experiences.

43:10- Yeah, what later helped bring this function

43:14into better focus was a distinction

43:17between controlled and automatic behavior.

43:19In other literatures, this is referred to

43:23as habitual behavior versus goal-directed behavior.

43:28So it's very, very clear that the human brain

43:33has pathways that are dedicated to habits,

43:36to things that you do all the time.

43:39And they need to be automatized

43:42so that they don't require you to concentrate too much.

43:45So that leaves your cognitive capacity

43:47for you to do other things.

43:49Just think about the difference between driving

43:54when you're learning to drive

43:55versus driving after you're fairly expert.

43:59There are brain pathways that slowly absorb

44:03those frequently performed behaviors

44:07so that they can be habits, so that they can be automatic.

44:12- That's kind of like the purest form of learning,

44:14I guess, is happening there, which is why,

44:18I mean, this is kind of jumping ahead,

44:20which is why that perhaps is the most useful

44:22for us to focusing on and trying to see

44:24how artificial intelligence systems can learn.

44:27Is that the way you think? - It's interesting.

44:28I do think about this distinction

44:30between controlled and automatic,

44:31or goal-directed and habitual behavior a lot

44:34in thinking about where we are in AI research.

44:38But just to finish the kind of dissertation here,

44:46the role of the prefrontal cortex

44:51is generally understood these days

44:54sort of in contradistinction to that habitual domain.

44:59In other words, the prefrontal cortex

45:02is what helps you override those habits.

45:05It's what allows you to say,

45:07"Whoa, whoa, what I usually do in this situation is X,

45:10"but given the context, I probably should do Y."

45:14I mean, the elbow bump is a great example, right?

45:18Reaching out and shaking hands

45:19is probably a habitual behavior,

45:22and it's the prefrontal cortex that allows us

45:26to bear in mind that there's something unusual

45:28going on right now, and in this situation,

45:31I need to not do the usual thing.

45:33The kind of behaviors that Luria reported,

45:38and he built tests for detecting these kinds of things,

45:42were exactly like this.

45:43So in other words, when I stick out my hand,

45:46I want you instead to present your elbow.

45:49A patient with frontal damage

45:51would have a great deal of trouble with that.

45:53Somebody proffering their hand would elicit a handshake.

45:57The prefrontal cortex is what allows us to say,

46:00"Hold on, hold on, that's the usual thing,

46:03"but I have the ability to bear in mind

46:07"even very unusual contexts,

46:09"and to reason about what behavior is appropriate there."

46:13- Just to get a sense, is us humans special

46:17in the presence of the prefrontal cortex?

46:20Do mice have a prefrontal cortex?

46:22Do other mammals that we can study?

46:25If no, then how do they integrate new experiences?

46:30- Yeah, that's a really tricky question,

46:33and a very timely question,

46:35because we have revolutionary new technologies

46:41for monitoring, measuring,

46:48and also causally influencing neural behavior

46:52in mice and fruit flies.

46:57And these techniques are not fully available

47:00even for studying brain function in monkeys,

47:05let alone humans.

47:07And so it's a very,

47:11sort of, for me at least, a very urgent question

47:14whether the kinds of things that we wanna understand

47:16about human intelligence can be pursued

47:20in these other organisms.

47:21And to put it briefly, there's disagreement.

47:27You know, people who study fruit flies will often tell you,

47:32"Hey, fruit flies are smarter than you think."

47:35And they'll point to experiments

47:36where fruit flies were able to learn new behaviors,

47:40were able to generalize from one stimulus to another

47:44in a way that suggests that they have abstractions

47:47that guide their generalization.

47:49I've had many conversations in which

47:54I will start by observing, you know,

47:58recounting some observation about mouse behavior,

48:03where it seemed like mice were taking an awfully long time

48:09to learn a task that for a human would be profoundly trivial.

48:13And I will conclude from that

48:16that mice really don't have the cognitive flexibility

48:18that we want to explain.

48:20And then a mouse researcher will say to me,

48:21"Well, you know, hold on.

48:24"That experiment may not have worked

48:26"because you asked a mouse to deal with stimuli

48:31"and behaviors that were very unnatural for the mouse.

48:34"If instead you kept the logic of the experiment the same,

48:38"but kind of put it in a, you know,

48:41"presented the information in a way

48:44"that aligns with what mice are used to dealing with

48:46"in their natural habitats,

48:48"you might find that a mouse actually has more intelligence

48:50"than you think."

48:52And then they'll go on to show you videos

48:54of mice doing things in their natural habitat,

48:57which seem strikingly intelligent, you know,

49:00dealing with, you know, physical problems, you know,

49:02I have to drag this piece of food back to my, you know,

49:06back to my lair, but there's something in my way

49:08and how do I get rid of that thing?

49:10So I think these are open questions to put it,

49:13you know, to sum that up.

49:15- And then taking a small step back related to that

49:18is you kind of mentioned we're taking a little shortcut

49:21by saying it's a geographic part of the,

49:25the prefrontal cortex is a region of the brain,

49:28but if we, what's your sense in a bigger philosophical view,

49:33prefrontal cortex and the brain in general?

49:36Do you have a sense that it's a set of subsystems

49:38in the way we've kind of implied

49:41that are pretty distinct?

49:43Or to what degree is it that,

49:46or to what degree is it a giant interconnected mess

49:49where everything kind of does everything

49:51and it's impossible to disentangle them?

49:53- I think there's overwhelming evidence

49:57that there's functional differentiation,

50:00that it's clearly not the case,

50:03that all parts of the brain are doing the same thing.

50:07This follows immediately from the kinds of studies

50:11of brain damage that we were chatting about before.

50:14It's obvious from what you see

50:18if you stick an electrode in the brain

50:19and measure what's going on

50:21at the level of neural activity.

50:24Having said that, there are two other things to add,

50:30which kind of, I don't know,

50:32maybe tug in the other direction.

§06Transcript · 50:34–1:00:52

50:34One is that it's when you look carefully

50:39at functional differentiation in the brain,

50:42what you usually end up concluding,

50:45at least this is my observation of the literature,

50:48is that the differences between regions are graded

50:52rather than being discrete.

50:55So it doesn't seem like it's easy

50:57to divide the brain up into true modules

51:01that have clear boundaries

51:06and that have clear channels of communication between them.

51:12- And this applies to the prefrontal cortex?

51:18- Yeah, oh yeah.

51:18Yeah, the prefrontal cortex is made up

51:20of a bunch of different sub-regions,

51:22the functions of which are not clearly defined

51:27and the borders of which seem to be quite vague.

51:30And then there's another thing that's popping up

51:34in very recent research,

51:36which involves application of these new features.

51:41Application of these new techniques,

51:43which there are a number of studies that suggest

51:47that parts of the brain

51:49that we would have previously thought

51:51were quite focused in their function

51:56are actually carrying signals

51:59that we wouldn't have thought would be there.

52:01For example, looking in the primary visual cortex,

52:04which is classically thought of as basically

52:07the first cortical way station

52:09for processing visual information.

52:10Basically what it should care about is,

52:12where are the edges in this scene that I'm viewing?

52:15It turns out that if you have enough data,

52:19you can recover information from primary visual cortex

52:22about all sorts of things,

52:23like what behavior the animal is engaged in right now

52:26and how much reward is on offer

52:29in the task that it's pursuing.

52:31So it's clear that even regions

52:35whose function is pretty well defined at a coarse grain

52:40are nonetheless carrying some information

52:42about information from very different domains.

52:47So the history of neuroscience is sort of this oscillation

52:51between the two views that you articulated,

52:54the kind of modular view and then the big mush view.

52:57And I think, I guess we're gonna end up

53:01somewhere in the middle,

53:02which is unfortunate for our understanding

53:05because there's something about our conceptual system

53:10that finds it easy to think about a modularized system

53:12and easy to think about a completely undifferentiated system,

53:15but something that kind of lies in between is confusing,

53:19but we're gonna have to get used to it, I think.

53:21- Unless we can understand deeply

53:23the lower level mechanism of neuronal communication.

53:25- Yeah, yeah.

53:26- So on that topic, you kind of mentioned information.

53:29Just to get a sense, I imagine something

53:31that there's still mystery and disagreement on

53:34is how does the brain carry information and signal?

53:38Like what in your sense is the basic mechanism

53:43of communication in the brain?

53:46- Well, I guess I'm old fashioned in that

53:50I consider the networks that we use

53:53in deep learning research to be a reasonable approximation

53:57to the mechanisms that carry information in the brain.

54:02So the usual way of articulating that is to say,

54:06what really matters is a rate code.

54:08What matters is how quickly is an individual neuron spiking?

54:13What's the frequency at which it's spiking?

54:16- So the timing of the spike.

54:17- Yeah, is it firing fast or slow?

54:20Let's put a number on that.

54:22And that number is enough to capture what neurons are doing.

54:26There's still uncertainty about whether

54:31that's an adequate description of how information

54:35is transmitted within the brain.

54:39There are studies that suggest that the precise timing

54:44of spikes matters.

54:46There are studies that suggest that there are computations

54:50that go on within the dendritic tree, within a neuron

54:54that are quite rich and structured

54:57and that really don't equate to anything that we're doing

54:59in our artificial neural networks.

55:02Having said that, I feel like we're getting somewhere

55:07by sticking to this high level of abstraction.

55:11- Just the rate, and by the way,

55:13we're talking about the electrical signal.

55:16I remember reading some vague paper somewhere recently

55:20where the mechanical signal, like the vibrations

55:23or something of the neurons also communicates information.

55:28- I haven't seen that.

55:30- So there's somebody was arguing that

55:33the electrical signal, this is in Nature paper,

55:36something like that, where the electrical signal

55:38is actually a side effect of the mechanical signal.

55:43But I don't think that changes the story.

55:46But it's almost an interesting idea

55:49that there could be a deeper, it's always like in physics

55:52with quantum mechanics, there's always a deeper story

55:55that could be underlying the whole thing.

55:57But you think it's basically the rate of spiking

56:00that gets us, that's like the lowest hanging fruit

56:02that can get us really far.

56:04- This is a classical view.

56:06I mean, this is not, the only way in which this stance

56:10would be controversial is in the sense that

56:14there are members of the neuroscience community

56:17who are interested in alternatives.

56:18But this is really a very mainstream view.

56:21The way that neurons communicate is that

56:25neurotransmitters arrive,

56:27they wash up on a neuron,

56:32the neuron has receptors for those transmitters.

56:35The meeting of the transmitter with these receptors

56:39changes the voltage of the neuron.

56:42And if enough voltage change occurs,

56:45then a spike occurs, right?

56:46One of these like discrete events.

56:48And it's that spike that is conducted down the axon

56:52and leads to neurotransmitter release.

56:54This is just like neuroscience 101.

56:56This is like the way the brain is supposed to work.

56:59Now, what we do when we build artificial neural networks

57:03of the kind that are now popular in the AI community

57:06is that we don't worry about those individual spikes.

57:11We just worry about the frequency

57:14at which those spikes are being generated.

57:16And we consider, people talk about that

57:19as the activity of a neuron.

57:22And so the activity of units in a deep learning system

57:27is broadly analogous to the spike rate of a neuron.

57:32There are people who believe

57:37that there are other forms of communication in the brain.

57:39In fact, I've been involved in some research recently

57:41that suggests that the voltage fluctuations

57:46that occur in populations of neurons

57:49that are sort of below the level of spike production

57:54may be important for communication.

57:57But I'm still pretty old school in the sense

58:00that I think that the things that we're building

58:03in AI research constitute reasonable models

58:07of how a brain would work.

58:08- Let me ask just for fun a crazy question, 'cause I can.

58:14Do you think it's possible we're completely wrong

58:17about the way this basic mechanism

58:20of neuronal communication,

58:22that the information is stored

58:24in some very different kind of way in the brain?

58:26- Oh, heck yes.

58:27I mean, look, I wouldn't be a scientist

58:29if I didn't think there was any chance we were wrong.

58:32But I mean, if you look at the history

58:36of deep learning research

58:38as it's been applied to neuroscience,

58:41of course, the vast majority of deep learning research

58:43these days isn't about neuroscience.

58:45But if you go back to the 1980s,

58:49there's sort of an unbroken chain of research

58:52in which a particular strategy is taken,

58:55which is, hey, let's train a deep learning system.

59:00Let's train a multilayer neural network

59:04on this task that we trained our rat on,

59:09or our monkey on, or this human being on.

59:12And then let's look at what the units

59:15deep in the system are doing.

59:17And let's ask whether what they're doing

59:20resembles what we know about

59:22what neurons deep in the brain are doing.

59:24And over and over and over and over,

59:28that strategy works in the sense that

59:31the learning algorithms that we have access to,

59:34which typically center on back propagation,

59:37they give rise to patterns of activity,

59:42patterns of response,

59:44patterns of neuronal behavior in these artificial models

59:48that look hauntingly similar to what you see in the brain.

59:53And is that a coincidence?

59:57- At a certain point, it starts looking like

59:59such coincidence is unlikely to not be deeply meaningful.

60:03Yeah. - Yeah.

60:03The circumstantial evidence is overwhelming.

60:07But it could-- - But you're always open

60:08to a total flipping of the table.

60:10- Hey, of course.

60:11So you have co-authored several recent papers

60:15that sort of weave beautifully between the world

60:17of neuroscience and artificial intelligence.

60:20And maybe if we could,

60:24can we just try to dance around and talk about some of them,

60:27maybe try to pick out interesting ideas

60:29that jump to your mind from memory.

60:32So maybe looking at,

60:33we were talking about the prefrontal cortex,

60:35the 2018, I believe, paper called

60:38"Prefrontal Cortex as a Meta-Reinforcement Learning System."

60:42What, is there a key idea

60:44that you can speak to from that paper?

60:46- Yeah, I mean, the key idea is about meta-learning.

60:52So-- - What is meta-learning?

§07Transcript · 1:00:54–1:10:15

60:54- Meta-learning is, by definition,

60:58a situation in which you have a learning algorithm,

61:06and the learning algorithm operates in such a way

61:09that it gives rise to another learning algorithm.

61:14In the earliest applications of this idea,

61:17you had one learning algorithm sort of adjusting

61:20the parameters on another learning algorithm.

61:23But the case that we're interested in this paper

61:25is one where you start with just one learning algorithm,

61:29and then another learning algorithm kind of emerges

61:33out of thin air.

61:35I can say more about what I mean by that.

61:36I don't mean to be, you know,

61:38(Michael laughs)

61:39ascurantist, but that's the idea of meta-learning.

61:43It relates to the old idea in psychology

61:46of learning to learn.

61:47Situations where you have experiences

61:54that make you better at learning something new.

61:57Like a familiar example would be learning a foreign language.

62:01The first time you learn a foreign language,

62:02it may be quite laborious and disorienting and novel.

62:07But if, let's say you've learned two foreign languages,

62:12the third foreign language, obviously,

62:14is gonna be much easier to pick up.

62:15And why?

62:16Because you've learned how to learn.

62:18You know how this goes.

62:20You know, okay, I'm gonna have to learn how to conjugate.

62:22I'm gonna have to...

62:23That's a simple form of meta-learning, right?

62:26In the sense that there's some slow learning mechanism

62:30that's helping you kind of update

62:33your fast learning mechanism.

62:34Does that bring it into focus?

62:36- So how, from our understanding,

62:39from the psychology world, from neuroscience,

62:42our understanding how meta-learning works

62:45might work in the human brain,

62:47what lessons can we draw from that

62:50that we can bring into the artificial intelligence world?

62:53- Well, yeah, so the origin of that paper

62:55was in AI work that we were doing in my group.

63:00We were looking at what happens

63:03when you train a recurrent neural network

63:06using standard reinforcement learning algorithms.

63:10But you train that network, not just in one task,

63:12but you train it in a bunch of interrelated tasks.

63:15And then you ask what happens

63:17when you give it yet another task

63:19in that sort of line of interrelated tasks.

63:23And what we started to realize is that

63:29a form of meta-learning spontaneously happens

63:31in recurrent neural networks.

63:33And the simplest way to explain it is to say

63:37a recurrent neural network has a kind of memory

63:43in its activation patterns.

63:45It's recurrent by definition in the sense

63:47that you have units that connect to other units

63:50that connect to other units.

63:51So you have sort of loops of connectivity,

63:53which allows activity to stick around

63:55and be updated over time.

63:57In psychology, we call, in neuroscience,

63:59we call this working memory.

64:00It's like actively holding something in mind.

64:03And so that memory gives the recurrent neural network

64:10a dynamics, right?

64:13The way that the activity pattern evolves over time

64:17is inherent to the connectivity

64:19of the recurrent neural network, okay?

64:21So that's idea number one.

64:23Now, the dynamics of that network

64:25are shaped by the connectivity, by the synaptic weights.

64:29And those synaptic weights are being shaped

64:31by this reinforcement learning algorithm

64:33that you're training the network with.

64:35So the punchline is,

64:39if you train a recurrent neural network

64:41with a reinforcement learning algorithm

64:43that's adjusting its weights,

64:44and you do that for long enough,

64:45the activation dynamics will become very interesting, right?

64:50So imagine I give you a task

64:53where you have to press one button or another,

64:56left button or right button.

64:57And there's some probability

65:00that I'm gonna give you an M&M

65:02if you press the left button,

65:04and there's some probability I'll give you an M&M

65:06if you press the other button.

65:07And you have to figure out what those probabilities are

65:09just by trying things out.

65:10But as I said before,

65:13instead of just giving you one of these tasks,

65:15I give you a whole sequence.

65:16You know, I give you two buttons

65:18and you figure out which one's best,

65:19and I go, "Good job, here's a new box,

65:22two new buttons, you have to figure out which one's best.

65:24Good job, here's a new box."

65:25And every box has its own probabilities

65:27and you have to figure it.

65:28So if you train a recurrent neural network

65:30on that kind of sequence of tasks,

65:32what happens, it seemed almost magical to us

65:37when we first started kind of realizing what was going on.

65:41The slow learning algorithm

65:42that's adjusting the synaptic weights,

65:45those slow synaptic changes give rise to a network dynamics

65:51that themselves, that, you know,

65:52the dynamics themselves turn into a learning algorithm.

65:56So in other words, you can tell this is happening

65:59by just freezing the synaptic weights, saying,

66:00"Okay, no more learning, you're done.

66:03Here's a new box, figure out which button is best."

66:07And the recurrent neural network will do this just fine.

66:09There's no, like it figures out which button is best.

66:13It kind of transitions from exploring the two buttons

66:16to just pressing the one that it likes best

66:18in a very rational way.

66:20How is that happening?

66:21It's happening because the activity dynamics of the network

66:25have been shaped by the slow learning process

66:28that's occurred over many, many boxes.

66:30And so what's happened is that this slow learning algorithm

66:34that's slowly adjusting the weights

66:37is changing the dynamics of the network,

66:39the activity dynamics into its own learning algorithm.

66:43And as we were kind of realizing that this is a thing,

66:49it just so happened that the group that was working on this

66:53included a bunch of neuroscientists.

66:56And it started kind of ringing a bell for us,

66:59which is to say that we thought,

67:01"This sounds a lot like the distinction

67:03between synaptic learning and activity,

67:07synaptic memory and activity-based memory in the brain."

67:10And it also reminded us of recurrent connectivity

67:15that's very characteristic of prefrontal function.

67:18So this is kind of why it's good to have people working

67:22on AI that know a little bit about neuroscience

67:26and vice versa, because we started thinking about

67:29whether we could apply this principle to neuroscience.

67:32And that's where the paper came from.

67:33- So the kind of principle of the recurrence

67:37they can see in the prefrontal cortex,

67:39then you start to realize that it's possible

67:42to force something like an idea of a learning to learn,

67:47emerging from this learning process,

67:50as long as you keep varying the environment sufficiently.

67:54- Exactly.

67:55So the kind of metaphorical transition

67:59we made to neuroscience was to think,

68:00"Okay, well, we know that the prefrontal cortex

68:03is highly recurrent.

68:05We know that it's an important locus for working memory,

68:08for activation-based memory.

68:11So maybe the prefrontal cortex

68:13supports reinforcement learning."

68:15In other words, what is reinforcement learning?

68:19You take an action, you see how much reward you got,

68:21you update your policy of behavior.

68:23Maybe the prefrontal cortex is doing that sort of thing

68:26strictly in its activation patterns.

68:28It's keeping around a memory in its activity patterns

68:31of what you did, how much reward you got,

68:35and it's using that activity-based memory

68:39as a basis for updating behavior.

68:41But then the question is,

68:42"Well, how did the prefrontal cortex get so smart?"

68:44In other words, where did these activity dynamics come from?

68:48How did that program that's implemented

68:50in the recurrent dynamics of the prefrontal cortex arise?

68:54And one answer that became evident in this work was,

68:58"Well, maybe the mechanisms that operate

69:00on the synaptic level,

69:02which we believe are mediated by dopamine,

69:06are responsible for shaping those dynamics."

69:10- So this may be a silly question,

69:12but because this kind of several temporal classes

69:17of learning are happening,

69:20and the learning-to-learnism emerges,

69:24can you keep building stacks of learning-to-learn-to-learn,

69:29learning-to-learn-to-learn-to-learn-to-learn,

69:31because it keeps, I mean, basically abstractions

69:34of more powerful abilities to generalize

69:38of learning complex rules?

69:41- Yeah.

69:41- Or is this overstretching this kind of mechanism?

69:46- Well, one of the people in AI

69:49who started thinking about meta-learning

69:52from very early on, Juergen and Schmidhuber,

69:55sort of cheekily suggested,

69:59I think it may have been in his PhD thesis,

70:03that we should think about meta, meta, meta,

70:06meta, meta, meta learning.

70:08You know, that's really what's gonna get us

70:11to true intelligence.

70:13- Certainly there's a poetic aspect to it,

70:15and it seems interesting and correct

§08Transcript · 1:10:19–1:19:37

70:19that that kind of level of abstraction would be powerful,

70:21but is that something you see in the brain?

70:23This kind of, is it useful to think of learning

70:27in these meta, meta, meta way,

70:29or is it just meta learning?

70:32- Well, one thing that really fascinated me

70:35about this mechanism that we were starting to look at,

70:39and other groups started talking about very similar things

70:43at the same time, and then a kind of explosion of interest

70:47in meta-learning happened in the AI community

70:48shortly after that.

70:50I don't know if we had anything to do with that,

70:52but I was gratified to see that a lot of people

70:55started talking about meta-learning.

70:57One of the things that I like about the kind of flavor

71:01of meta-learning that we were studying

71:03was that it didn't require anything special.

71:05It was just, if you took a system

71:07that had some form of memory,

71:10that the function of which could be shaped

71:13by pick your RL algorithm,

71:16then this would just happen.

71:18- Yes.

71:19- I mean, there are a lot of forms of,

71:21there are a lot of meta-learning algorithms

71:23that have been proposed since then

71:24that are fascinating and effective

71:26in their domains of application,

71:29but they're engineered.

71:31There are things that somebody had to say,

71:33well, gee, if we wanted meta-learning to happen,

71:34how would we do that?

71:35Here's an algorithm that would,

71:37but there's something about the kind of meta-learning

71:39that we were studying that seemed to me special

71:42in the sense that it wasn't an algorithm.

71:45It was just something that automatically happened

71:48if you had a system that had memory

71:51and it was trained with a reinforcement learning algorithm.

71:54And in that sense, it can be as meta as it wants to be.

71:59There's no limit on how abstract the meta-learning can get

72:04because it's not reliant on a human engineering

72:08a particular meta-learning algorithm to get there.

72:10And that's, I also, I don't know,

72:15I guess I hope that that's relevant in the brain.

72:17I think there's a kind of beauty

72:19in the ability of this emergent--

72:23- The emergent aspect of it.

72:24- Yeah, it's something that--

72:25- As opposed to engineered.

72:26- Exactly, it's something that just,

72:28it just happens in a sense.

72:31In a sense, you can't avoid this happening.

72:33If you have a system that has memory

72:35and the function of that memory

72:37is shaped by reinforcement learning,

72:41and this system is trained

72:42in a series of interrelated tasks,

72:45this is gonna happen, you can't stop it.

72:48- As long as you have certain properties,

72:50maybe like a recurrent structure to--

72:52- You have to have memory.

72:53It actually doesn't have to be a recurrent neural network.

72:55A paper that I was honored to be involved with even earlier

72:59used a kind of slot-based memory.

73:02- Do you remember the title?

73:03Just for people who watched it.

73:05- It was Memory Augmented Neural Networks.

73:08I think the title was

73:10Meta-Learning in Memory Augmented Neural Networks.

73:13And it was the same exact story.

73:17If you have a system with memory,

73:21here it was a different kind of memory,

73:22but the function of that memory

73:24is shaped by reinforcement learning.

73:28Here it was the reads and writes

73:32that occurred on this slot-based memory.

73:36This'll just happen.

73:38But this brings us back to something I was saying earlier

73:42about the importance of the environment.

73:44This will happen if the system is being trained

73:49in a setting where there's a sequence of tasks

73:53that all share some abstract structure.

73:55Sometimes we talk about task distributions.

73:59And that's something that's very obviously true

74:04of the world that humans inhabit.

74:06If you just kind of think about what you do every day,

74:12you never do exactly the same thing

74:16that you did the day before.

74:17But everything that you do has a family resemblance.

74:21It shares a structure with something that you did before.

74:23And so the real world is

74:26saturated with this property.

74:32It's endless variety with endless redundancy.

74:37And that's the setting

74:38in which this kind of meta-learning happens.

74:40- And it does seem like we're just so good at finding,

74:44just like in this emergent phenomenon

74:47you described, we're really good at finding that redundancy,

74:50finding those similarities, the family resemblance.

74:53Some people call it sort of, what is it?

74:56Melanie Mitchell was talking about analogies.

74:59So we're able to connect concepts together

75:01in this kind of way,

75:03in this same kind of automated emergent way.

75:06There's so many echoes here of psychology and neuroscience.

75:10And obviously now with reinforcement learning

75:15with recurrent neural networks at the core.

75:18If we could talk a little bit about dopamine,

75:20you have really, you're a part of co-authoring

75:23really exciting recent paper, very recent,

75:26in terms of release on dopamine

75:28and temporal difference learning.

75:31Can you describe the key ideas of that paper?

75:34- Sure, yeah.

75:35I mean, one thing I want to pause to do

75:37is acknowledge my co-authors on actually both

75:40of the papers we're talking about.

75:41So this dopamine paper--

75:43- I'll just, I'll certainly post all their names.

75:45- Okay, wonderful, yeah.

75:46'Cause I'm sort of a bash to be the spokesperson

75:50for these papers when I had such amazing collaborators

75:53on both.

75:55So it's a comfort to me to know

75:57that you'll acknowledge them.

75:58- Yeah, there's an incredible team there, but yeah.

76:00- Oh yeah, it's so much fun.

76:03And in the case of the dopamine paper,

76:06we also collaborated with Naoichi at Harvard,

76:09who obviously the paper simply wouldn't have happened

76:11without him.

76:12But so you were asking for like a thumbnail sketch of--

76:17- Yes, a thumbnail sketch or key ideas or things,

76:21the insights that continue on our kind of discussion here

76:24between neuroscience and AI.

76:26- Yeah, I mean, this was another,

76:28a lot of the work that we've done so far

76:30is taking ideas that have bubbled up in AI

76:35and asking the question of whether the brain

76:39might be doing something related,

76:41which I think on the surface sounds like something

76:45that's really mainly of use to neuroscience.

76:48We see it also as a way of validating what we're doing

76:54on the AI side.

76:55If we can gain some evidence that the brain

76:57is using some technique that we've been trying out

77:01in our AI work, that gives us confidence

77:05that it may be a good idea,

77:07that it'll scale to rich, complex tasks,

77:11that it'll interface well with other mechanisms.

77:14- So you see it as a two-way road.

77:16- Yeah, for sure.

77:17- Just because a particular paper is a little bit focused

77:19on from AI from neural networks to neuroscience,

77:24ultimately the discussion, the thinking,

77:28the productive long-term aspect of it

77:30is the two-way road nature of the whole--

77:33- Yeah, I mean, we've talked about the notion

77:36of a virtuous circle between AI and neuroscience.

77:39And the way I see it, that's always been there

77:43since the two fields jointly existed.

77:49There have been some phases in that history

77:52when AI was sort of ahead.

77:53There are some phases when neuroscience was sort of ahead.

77:56I feel like given the burst of innovation

78:00that's happened recently on the AI side,

78:03AI is kind of ahead in the sense that

78:06there are all of these ideas

78:07for which it's exciting to consider

78:12that there might be neural analogs.

78:14And neuroscience, in a sense,

78:20has been focusing on approaches to studying behavior

78:23that come from, that are kind of derived

78:26from this earlier era of cognitive psychology.

78:29And so in some ways,

78:32fail to connect with some of the issues

78:34that we're grappling with in AI,

78:36like how do we deal with large, complex environments?

78:40But I think it's inevitable

78:45that this circle will keep turning

78:47and there will be a moment

78:49in the not too distant future

78:51when neuroscience is pelting AI researchers

78:54with insights that may change the direction of our work.

78:58- Just a quick human question.

79:01You have parts of your brain,

79:05this is very meta,

79:06but they're able to both think about neuroscience and AI.

79:10You know, I don't often meet people like that.

79:14So do you think,

79:16let me ask a metaplasticity question.

79:19Do you think a human being can be both good at AI

79:22and neuroscience?

79:23Is like what, on the team at DeepMind,

79:26what kind of human can occupy these two realms?

79:30And is that something you see?

79:31Everybody should be doing, can be doing,

79:34or is that a very special few can kind of jump?

79:37Just like we talk about art history,

§09Transcript · 1:19:39–1:30:23

79:39I would think it's a special person

79:41that can major in art history

79:43and also consider being a surgeon.

79:46- Otherwise known as a dilettante.

79:48- A dilettante, yeah.

79:50Easily distracted.

79:51- I think it does take a special kind of person

79:58to be truly world-class at both AI and neuroscience.

80:02And I am not on that list.

80:04I happen to be someone

80:08who's interest in neuroscience and psychology

80:11involved using the kinds of modeling techniques

80:17that are now very central in AI.

80:21And that sort of, I guess,

80:23bought me a ticket to be involved

80:25in all of the amazing things

80:26that are going on in AI research right now.

80:28I do know a few people

80:31who I would consider pretty expert on both fronts,

80:34and I won't embarrass them by naming them,

80:36but there are exceptional people out there

80:40who are like this.

80:41The one thing that I find is a barrier

80:46to being truly world-class on both fronts

80:49is just the complexity of the technology

80:55that's involved in both disciplines now.

80:58So the engineering expertise that it takes

81:03to do truly frontline, hands-on AI research

81:08is really, really considerable.

81:10- The learning curve of the tools,

81:12just like the specifics of just,

81:14whether it's programming or the kind of tools necessary

81:16to collect the data, to manage the data,

81:18to distribute, to compute, all that kind of stuff.

81:20And on the neuroscience, I guess, side,

81:22there'll be all different sets of tools.

81:24- Exactly, especially with the recent explosion

81:26in neuroscience methods.

81:28So having said all that,

81:32I think the best scenario for both neuroscience and AI

81:40is to have people who, interacting,

81:45who live at every point on this spectrum,

81:49from exclusively focused on neuroscience

81:52to exclusively focused on the engineering side of AI.

81:56But to have those people inhabiting a community

82:01where they're talking to people

82:03who live elsewhere on the spectrum.

82:05And I may be someone who's very close to the center

82:09in the sense that I have one foot in the neuroscience world

82:13and one foot in the AI world.

82:15And that central position, I will admit,

82:18prevents me, at least someone

82:20with my limited cognitive capacity,

82:22from having true technical expertise in either domain.

82:27But at the same time, I at least hope

82:31that it's worthwhile having people around

82:33who can kind of see the connections between these two.

82:37- Yeah, the emergent intelligence of the community

82:41when it's nicely distributed is useful.

82:44Okay, so-- - Exactly, yeah.

82:45So hopefully, I mean, I've seen that work out well

82:48at DeepMind.

82:50There are people who, I mean, even if you just focus

82:53on the AI work that happens at DeepMind,

82:56it's been a good thing to have some people around

83:00doing that kind of work whose PhDs are in neuroscience

83:03or psychology.

83:05Every academic discipline has its kind of blind spots

83:10and kind of unfortunate obsessions

83:15and its metaphors and its reference points.

83:18And having some intellectual diversity is really healthy.

83:23People get each other unstuck, I think.

83:28I see it all the time at DeepMind.

83:30And I like to think that the people

83:33who bring some neuroscience background to the table

83:35are helping with that.

83:37- So one of my, probably the deepest passion for me,

83:41what I would say, maybe we kind of spoke off mic

83:44a little bit about it, but that I think

83:48is a blind spot for at least robotics and AI folks

83:51is human-robot interaction, human-agent interaction.

83:55Maybe, do you have thoughts about how we reduce

84:00the size of that blind spot?

84:03Do you also share the feeling that not enough folks

84:07are studying this aspect of interaction?

84:10- Well, I'm actually pretty intensively interested

84:14in this issue now.

84:15And there are people in my group who've actually pivoted

84:19pretty hard over the last few years

84:20from doing more traditional cognitive psychology

84:24and cognitive neuroscience to doing experimental work

84:28on human-agent interaction.

84:30And there are a couple of reasons

84:32that I'm pretty passionately interested in this.

84:35One is, it's kind of the outcome of having thought

84:42for a few years now about what we're up to.

84:46Like, what are we doing?

84:49Like, what is this AI research for?

84:53So what does it mean to make the world a better place?

84:57I think, I'm pretty sure that means

84:59making life better for humans.

85:00And so how do you make life better for humans?

85:05That's a proposition that when you look at it carefully

85:10and honestly is rather horrendously complicated,

85:15especially when the AI systems that you're building

85:20are learning systems.

85:25They're not, you're not programming something

85:29that you then introduce to the world

85:31and it just works as programmed,

85:33like Google Maps or something.

85:34We're building systems that learn from experience.

85:39So that typically leads to AI safety questions.

85:43How do we keep these things from getting out of control?

85:45How do we keep them from doing things that harm humans?

85:49And I mean, I hasten to say,

85:51I consider those hugely important issues.

85:54And there are large sectors of the research community

85:58at DeepMind and of course elsewhere,

86:00who are dedicated to thinking hard all day,

86:03every day about that.

86:04But there's, I guess I would say a positive side to this too

86:09which is to say, well,

86:11what would it mean to make human life better?

86:15And how can we imagine learning systems doing that?

86:20And in talking to my colleagues about that,

86:23we reached the initial conclusion that

86:26it's not sufficient to philosophize about that.

86:30You actually have to take into account

86:32how humans actually work and what humans want

86:37and the difficulties of knowing what humans want

86:40and the difficulties that arise

86:43when humans want different things.

86:46And so human agent interaction has become

86:50a quite intensive focus of my group lately.

86:55If for no other reason that,

86:58in order to really address that issue in an adequate way,

87:04you have to, I mean, psychology becomes part of the picture.

87:07- And so there's a few elements there.

87:10So if you focus on solving,

87:12if you focus on the robotics problem,

87:14let's say AGI without humans in the picture,

87:17you're missing fundamentally the final step.

87:22When you do want to help human civilization,

87:24you eventually have to interact with humans.

87:27And when you create a learning system, just as you said,

87:31that will eventually have to interact with humans,

87:34the interaction itself has to become

87:39part of the learning process.

87:40So you can't just watch, well, my sense is,

87:43it sounds like your sense is,

87:45you can't just watch humans to learn about humans.

87:48You have to also be part of the human world.

87:50You have to interact with humans.

87:51- Yeah, exactly.

87:52And I mean, then questions arise that start imperceptibly,

87:57but inevitably to slip beyond the realm of engineering.

88:02So questions like, if you have an agent

88:06that can do something that you can't do,

88:08under what conditions do you want that agent to do it?

88:13So if I have a robot that can play Beethoven sonatas

88:18better than any human, in the sense that the sensitivity,

88:30the expression is just beyond what any human,

88:33do I wanna listen to that?

88:36Do I wanna go to a concert and hear a robot play?

88:38These aren't engineering questions.

88:41These are questions about human preference

88:44and human culture.

88:45- Psychology bordering on philosophy.

88:47- Yeah.

88:48And then you start asking,

88:50well, even if we knew the answer to that,

88:54is it our place as AI engineers

88:57to build that into these agents?

88:59Probably the agents should interact with humans

89:02beyond the population of AI engineers

89:05and figure out what those humans want.

89:07And then when you start, I referred this the moment ago,

89:11but even that becomes complicated.

89:14Be quote, what if two humans want different things

89:19and you have only one agent that's able to interact with them

89:22and try to satisfy their preferences?

89:24Then you're into the realm of

89:26of like economics and social choice theory

89:31and even politics.

89:33So there's a sense in which,

89:35if you kind of follow what we're doing

89:37to its logical conclusion,

89:39then it goes beyond questions of engineering and technology

89:44and starts to shade in perceptibly into questions about

89:49what kind of society do you want?

89:51And actually that, once that dawned on me,

89:55I actually felt,

89:57I don't know what the right word is,

89:59quite refreshed in my involvement in AI research.

90:03It was almost like building this kind of stuff

90:06is gonna lead us back to asking

90:08really fundamental questions about,

90:10what's the good life and who gets to decide?

90:16And bringing in viewpoints from multiple sub-communities

90:23to help us shape the way that we live.

§10Transcript · 1:30:26–1:39:58

90:26It started making me feel like doing AI research

90:32in a fully responsible way

90:35could potentially lead to a kind of cultural renewal.

90:42- Yeah, it's the way to understand human beings

90:47at the individual, the societal level.

90:50It may become a way to answer all the

90:52silly human questions of the meaning of life

90:54and all those kinds of things.

90:57- Even if it doesn't give us a way

90:58of answering those questions,

90:59it may force us back to thinking about them.

91:02- Thinking about them.

91:03- And it might restore a certain, I don't know,

91:07a certain depth to,

91:10or even dare I say, spirituality to the world.

91:15I don't know, maybe that's too grandiose.

91:19- Well, I'm with you.

91:21I think AI will be the philosophy of the 21st century,

91:26the way which will open the door.

91:28I think a lot of AI researchers are afraid to open that door

91:32of exploring the beautiful richness

91:35of the human-agent interaction, human-AI interaction.

91:39I'm really happy that somebody like you

91:42have opened that door.

91:44- One thing I often think about is the usual schema

91:49for thinking about human-agent interaction

91:54is this kind of dystopian,

91:56oh, our robot overlords.

92:00And again, I hasten to say AI safety is hugely important.

92:03And I'm not saying we shouldn't be thinking

92:06about those risks, totally on board for that.

92:09But there's,

92:10having said that,

92:14what often follows for me is the thought

92:18that there's another kind of narrative

92:23that might be relevant, which is when we think of humans

92:28gaining more and more information about human life,

92:33the narrative there is usually that they gain

92:37more and more wisdom and they get closer to enlightenment

92:40and they become more benevolent.

92:43Like the Buddha is like,

92:45that's a totally different narrative.

92:47And why isn't it the case that we imagine

92:50that the AI systems that we're creating

92:52are just gonna, they're gonna figure out more and more

92:54about the way the world works

92:55and the way that humans interact

92:56and they'll become beneficent.

92:59I'm not saying that will happen.

93:00I don't honestly expect that to happen

93:05without some careful, setting things up very carefully.

93:08But it's another way things could go, right?

93:11- Yeah, and I would even push back on that.

93:14I personally believe that the most trajectories,

93:19natural human trajectories will lead us towards progress.

93:25So for me, there is a kind of sense

93:28that most trajectories in AI development

93:30will lead us into trouble.

93:32To me, and we over-focus on the worst case.

93:37It's like in computer science,

93:38theoretical computer science has been

93:40this focus on worst case analysis.

93:42There's something appealing to our human mind

93:45at some lowest level to be,

93:47I mean, we don't wanna be eaten by the tiger, I guess.

93:50So we wanna do the worst case analysis.

93:52But the reality is that shouldn't stop us

93:55from actually building out all the other trajectories

93:58which are potentially leading to all the positive worlds,

94:02all the enlightenment.

94:04There's a book, "Enlightenment Now"

94:05with Steven Pinker and so on.

94:07This is looking generally at human progress.

94:09And there's so many ways that human progress

94:12can happen with AI.

94:13And I think you have to do that research.

94:16You have to do that work.

94:17You have to do the, not just the AI safety work

94:20of the one worst case analysis, how do we prevent that?

94:23But the actual tools and the glue

94:27and the mechanisms of human AI interaction

94:31that would lead to all the positive actions that can go.

94:34- Yeah, right.

94:35- It's a super exciting area, right?

94:36- Yeah, we should be spending,

94:38we should be spending a lot of our time saying

94:40what can go wrong?

94:42I think it's harder to see that there's work to be done

94:47to bring into focus the question of what it would look like

94:51for things to go right.

94:53That's not obvious.

94:56And we wouldn't be doing this

94:58if we didn't have the sense there was huge potential.

95:01We're not doing this for no reason.

95:05We have a sense that AGI would be a major boom to humanity.

95:10But I think it's worth starting now,

95:13even when our technology is quite primitive,

95:15asking, well, exactly what would that mean?

95:19We can start now with applications

95:21that are already gonna make the world a better place,

95:22like solving protein folding.

95:25I think this deep mind has gotten heavy

95:28into science applications lately,

95:30which I think is a wonderful, wonderful move

95:34for us to be making.

95:36But when we think about AGI,

95:37when we think about building fully intelligent agents

95:41that are gonna be able to, in a sense,

95:42do whatever they want,

95:44we should start thinking about

95:46what do we want them to want?

95:49What kind of world do we wanna live in?

95:52That's not an easy question.

95:54And I think we just need to start working on it.

95:56- And even on the path to sort of,

95:58it doesn't have to be AGI,

96:00but just intelligent agents that interact with us

96:02and help us enrich our own existence on social networks,

96:06for example, on recommender systems, various intelligent,

96:09there's so much interesting interaction

96:10that's yet to be understood and studied.

96:12And how do you create,

96:14I mean, Twitter is struggling with this very idea,

96:19how do you create AI systems

96:21that increase the quality and the health of a conversation?

96:24- For sure, yeah.

96:25- That's a beautiful, beautiful human psychology question.

96:28- And how do you do that

96:29without deception being involved,

96:34without manipulation being involved,

96:37maximizing human autonomy?

96:42And how do you make these choices in a democratic way?

96:46How do we face the,

96:50again, I'm speaking for myself here.

96:53How do we face the fact that

96:55it's a small group of people

96:58who have the skillset to build these kinds of systems,

97:02but what it means to make the world a better place

97:08is something that we all have to be talking about.

97:11- Yeah, the world that we're trying to make a better place

97:16includes a huge variety of different kinds of people.

97:20- Yeah, how do we cope with that?

97:22This is a problem that has been discussed

97:25in gory, extensive detail

97:27in social choice theory.

97:30One thing I'm really enjoying

97:32about the recent direction work has taken

97:35in some parts of my team is that,

97:36yeah, we're reading the AI literature,

97:38we're reading the neuroscience literature,

97:39but we've also started reading economics

97:42and, as I mentioned, social choice theory,

97:44even some political theory,

97:45because it turns out that it all becomes relevant.

97:50It all becomes relevant.

97:51But at the same time,

97:55we've been trying not to write philosophy papers, right?

98:00We've been trying not to write physician papers.

98:01We're trying to figure out ways

98:03of doing actual empirical research

98:05that kind of take the first small steps

98:07to thinking about what it really means

98:10for humans with all of their complexity and contradiction

98:14and paradox to be brought into contact

98:19with these AI systems in a way

98:22that really makes the world a better place.

98:25- And often reinforcement learning frameworks

98:27actually kind of allow you to do that machine learning.

98:31And so that's the exciting thing about AI

98:33is it allows you to reduce the unsolvable problem,

98:37philosophical problem,

98:38into something more concrete that you can get a hold of.

98:41- Yeah, and it allows you to kind of define the problem

98:43in some way that allows for growth in the system

98:48that's sort of, you know,

98:51you're not responsible for the details, right?

98:54You say, this is generally what I want you to do.

98:56And then learning takes care of the rest.

98:59Of course, the safety issues are, you know,

99:02arise in that context.

99:04But I think also some of these positive issues

99:05arise in that context.

99:06What would it mean for an AI system

99:09to really come to understand what humans want?

99:12And, you know, with all of the subtleties of that, right?

99:18You know, humans want help with certain things.

99:24But they don't want everything done for them, right?

99:27There is part of the satisfaction that humans get from life

99:30is in accomplishing things.

99:32So if there were devices around that did everything for,

99:34you know, I often think of the movie "Wall-E", right?

99:37That's like dystopian in a totally different way.

99:39It's like, the machines are doing everything for us.

99:41That's not what we wanted.

99:43You know, anyway, I just, I find this, you know,

99:46this opens up a whole landscape of research

99:50that feels affirmative and exciting.

99:52- To me, it's one of the most exciting and it's wide open.

99:56We have to, 'cause it's a cool paper,

99:58talk about dopamine.

§11Transcript · 1:39:59–1:48:54

99:59- Oh yeah, okay, so I can.

100:01We were gonna, we were gonna,

100:02I was gonna give you a quick summary.

100:05- Yeah, a quick summary of, what's the title of the paper?

100:10- I think we called it a distributional code for value

100:15in dopamine-based reinforcement learning.

100:18- Yes.

100:19So that's another project that grew out of pure AI research.

100:24A number of people at DeepMind and a few other places

100:30had started working on a new version

100:33of reinforcement learning, which was defined

100:37by taking something in traditional reinforcement learning

100:41and just tweaking it.

100:42So the thing that they took

100:43from traditional reinforcement learning was a value signal.

100:47So at the center of reinforcement learning,

100:50at least most algorithms, is some representation

100:53of how well things are going,

100:54your expected cumulative future reward.

100:58And that's usually represented as a single number.

101:01So if you imagine a gambler in a casino

101:04and the gambler's thinking, well,

101:07I have this probability of winning

101:09such and such an amount of money,

101:10and I have this probability of losing

101:11such and such an amount of money,

101:13that situation would be represented as a single number,

101:16which is like the expected,

101:17the weighted average of all those outcomes.

101:20And this new form of reinforcement learning said,

101:24well, what if we generalize that

101:26to a distributional representation?

101:28So now we think of the gambler as literally thinking,

101:31well, there's this probability

101:32that I'll win this amount of money,

101:34and there's this probability

101:35that I'll lose that amount of money,

101:36and we don't reduce that to a single number.

101:38And it had been observed through experiments,

101:42through just trying this out,

101:44that that kind of distributional representation

101:47really accelerated reinforcement learning

101:51and led to better policies.

101:54- What's your intuition about,

101:55so we're talking about rewards.

101:56- Yeah. - So what's your intuition

101:58why that is?

101:59Why does it depend? - Well, it's kind of

102:00a surprising historical note,

102:04at least surprised me when I learned it,

102:06that this had been tried out in a kind of heuristic way.

102:09People thought, well, gee, what would happen if we tried?

102:12And then it had this, empirically,

102:14it had this striking effect.

102:17And it was only then that people started thinking,

102:19well, gee, wait, why?

102:20Why?

102:21Wait, why?

102:22Why is this working?

102:23And that's led to a series of studies

102:26just trying to figure out why it works, which is ongoing.

102:29But one thing that's already clear from that research

102:31is that one reason that it helps

102:34is that it drives richer representation learning.

102:39So if you imagine two situations

102:43that have the same expected value,

102:45the same kind of weighted average value,

102:47standard deep reinforcement learning algorithms

102:51are going to take those two situations

102:53and kind of, in terms of the way

102:54they're represented internally,

102:56they're gonna squeeze them together.

102:58Because the thing that you're trying to represent,

103:02which is their expected value, is the same.

103:04So all the way through the system,

103:06things are gonna be mushed together.

103:08But what if those two situations

103:11actually have different value distributions?

103:13They have the same average value,

103:16but they have different distributions of value.

103:19In that situation, distributional learning

103:22will maintain the distinction between these two things.

103:25So to make a long story short,

103:26distributional learning can keep things separate

103:30in the internal representation

103:32that might otherwise be conflated or squished together.

103:35And maintaining those distinctions

103:36can be useful when the system

103:39is now faced with some other task

103:41where the distinction is important.

103:43- If we look at the optimistic

103:44and pessimistic dopamine neurons.

103:46So first of all, what is dopamine?

103:49- Oh, right. - And why is this,

103:53why is this at all useful to think about

103:56in the artificial intelligence sense?

104:00But what do we know about dopamine in the human brain?

104:04What is it, why is it useful, why is it interesting?

104:07What does it have to do with the prefrontal cortex

104:09and learning in general?

104:10- Yeah, so, well, this is also a case

104:15where there's a huge amount of detail and debate.

104:19But one currently prevailing idea

104:24is that the function of this neurotransmitter dopamine

104:29resembles a particular component

104:33of standard reinforcement learning algorithms,

104:36which is called the reward prediction error.

104:39So I was talking a moment ago

104:41about these value representations.

104:44How do you learn them?

104:45How do you update them based on experience?

104:46Well, if you made some prediction about future reward,

104:51and then you get more reward than you were expecting,

104:54then probably retrospectively,

104:55you wanna go back and increase the value representation

105:00that you attached to that earlier situation.

105:03If you got less reward than you were expecting,

105:06you should probably decrement that estimate.

105:08- And that's the process of temporal difference.

105:10- Exactly, this is the central mechanism

105:11of temporal difference learning,

105:12which is one of several kind of,

105:15you know, kind of back,

105:16sort of the backbone of our armamentarium in RL.

105:20And it was this connection

105:22between the reward prediction error and dopamine

105:25was made, you know, in the 1990s.

105:30And there's been a huge amount of research

105:33that, you know, seems to back it up.

105:35Dopamine may be doing other things,

105:37but this is clearly, at least roughly,

105:39one of the things that it's doing.

105:42But the usual idea was that dopamine

105:45was representing these reward prediction errors,

105:48again, in this like kind of single number way,

105:52representing your surprise with a single number.

105:56And in distributional reinforcement learning,

105:58this kind of new elaboration of the standard approach,

106:02it's not only the value function

106:06that's represented as a single number,

106:08it's also the reward prediction error.

106:10And so what happened was that Will Dabney,

106:15one of my collaborators,

106:17who was one of the first people to work

106:19on distributional temporal difference learning,

106:22talked to a guy in my group, Zeb Kurth-Nelson,

106:25who's a computational neuroscientist,

106:27and said, "Gee, you know, is it possible

106:29that dopamine might be doing something

106:31like this distributional coding thing?"

106:33And they started looking at what was in the literature,

106:36and then they brought me in,

106:37and we started talking to Nao Uchida,

106:39and we came up with some specific predictions about,

106:42you know, if the brain is using

106:43this kind of distributional coding,

106:45then in the tasks that Nao has studied,

106:47you should see this, this, this, and this.

106:49And that's where the paper came from.

106:50We kind of enumerated a set of predictions,

106:53all of which ended up being fairly clearly confirmed,

106:56and all of which leads to at least some initial indication

107:00that the brain might be doing something

107:02like this distributional coding,

107:03that dopamine might be representing surprise signals

107:06in a way that is not just collapsing everything

107:10to a single number, but instead is kind of respecting

107:12the variety of future outcomes, if that makes sense.

107:16- So yeah, so that's showing, suggesting possibly

107:19that dopamine has a really interesting representation scheme

107:23in the human brain for its reward signal.

107:27- Exactly. - That's fascinating.

107:29It's just, that's another beautiful example

107:31of AI revealing something nice about neuroscience.

107:34Potentially, suggesting possibilities.

107:36- Well, you never know, so the minute you publish a paper

107:38like that, the next thing you think is,

107:40"I hope that replicates, like, I hope we see

107:43"that same thing in other data sets."

107:44But of course, several labs now

107:47are doing the follow-up experiment,

107:49so we'll know soon.

107:50- That'd be interesting. - But it has been,

107:50it has been a lot of fun for us to take these ideas from AI

107:54and kind of bring them into neuroscience

107:56and see how far we can get.

107:58- So we kind of talked about it a little bit,

108:01but where do you see the field of neuroscience

108:03and artificial intelligence heading broadly?

108:07Like, what are the possible exciting areas

108:12that you can see breakthroughs in the next, let's get crazy,

108:16not just three or five years, but next 10, 20, 30 years

108:20that would make you excited and perhaps you'd be part of?

108:27- On the neuroscience side,

108:31there's a great deal of interest now

108:34in what's going on in AI.

108:36And at the same time, I feel like,

108:44so neuroscience, especially the part of neuroscience

108:49that's focused on circuits and systems,

108:54kind of like really mechanism-focused,

§12Transcript · 1:48:56–1:58:27

108:56there's been this explosion in new technology.

109:01And up until recently, the experiments

109:06that have exploited this technology

109:08have not involved a lot of interesting behavior.

109:13And this is for a variety of reasons,

109:15one of which is in order to employ

109:18some of these technologies, you actually have to,

109:21if you're studying a mouse, you have to head fix the mouse.

109:23In other words, you have to immobilize the mouse.

109:26And so it's been tricky to come up with ways

109:29of eliciting interesting behavior

109:30from a mouse that's restrained in this way.

109:33But people have begun to create

109:35very interesting solutions to this,

109:39like virtual reality environments

109:41where the animal can kind of move a trackball

109:43and as people have kind of begun to explore

109:48what you can do with these technologies,

109:50I feel like more and more people are asking,

109:52well, let's try to bring behavior into the picture.

109:55Let's try to like reintroduce behavior,

109:58which was supposed to be what this whole thing was about.

110:01And I'm hoping that those two trends,

110:06the kind of growing interest in behavior

110:10and the widespread interest in what's going on in AI,

110:15will come together to kind of open a new chapter

110:18in neuroscience research where there's a kind of

110:22a rebirth of interest in the structure of behavior

110:26and its underlying substrates,

110:28but that that research is being informed

110:32by computational mechanisms

110:34that we're coming to understand in AI.

110:36If we can do that, then we might be taking

110:39a step closer to this utopian future

110:42that we were talking about earlier,

110:43where there's really no distinction

110:45between psychology and neuroscience.

110:47Neuroscience is about studying the mechanisms

110:51that underlie whatever it is the brain is for,

110:55and what is the brain for?

110:56It's for behavior.

110:58I feel like we could maybe take a step toward that now

111:03if people are motivated in the right way.

111:05You also asked about AI.

111:08So that was a neuroscience question.

111:10- You said neuroscience, that's right.

111:12And especially a place like DeepMind,

111:13I'm interested in both branches.

111:15So what about the engineering of intelligence systems?

111:18- I think one of the key challenges

111:24that a lot of people are seeing now in AI

111:28is to build systems that have the kind of flexibility,

111:33and the kind of flexibility that humans have in two senses.

111:38One is that humans can be good at many things.

111:41They're not just expert at one thing.

111:44And they're also flexible in the sense

111:45that they can switch between things very easily,

111:49and they can pick up new things very quickly

111:52because they very ably see what a new task has in common

111:57with other things that they've done.

111:59And that's something that our AI systems

112:05just blatantly do not have.

112:09There are some people who like to argue

112:11that deep learning and deep RL

112:13are simply wrong for getting that kind of flexibility.

112:16I don't share that belief,

112:19but the simpler fact of the matter

112:22is we're not building things yet

112:23that do have that kind of flexibility.

112:25And I think the attention of a large part

112:28of the AI community is starting to pivot to that question.

112:31How do we get that?

112:32That's gonna lead to a focus on abstraction.

112:37It's gonna lead to a focus on what in psychology

112:41we call cognitive control,

112:43which is the ability to switch between tasks,

112:45the ability to quickly put together a program of behavior

112:49that you've never executed before,

112:51but you know makes sense for a particular set of demands.

112:55It's very closely related to what the prefrontal cortex does

112:59on the neuroscience side.

113:01So I think it's gonna be an interesting new chapter.

113:05- So that's the reasoning side and cognition side,

113:07but let me ask the over romanticized question.

113:10Do you think we'll ever engineer an AGI system

113:13that we humans would be able to love

113:17and then would love us back?

113:18So have that level and depth of connection.

113:23- I love that question.

113:27And it relates closely to things

113:31that I've been thinking about a lot lately,

113:33in the context of this human AI research.

113:36There's social psychology research,

113:40in particular by Susan Fisk at Princeton,

113:44in the department where I used to work,

113:47where she dissects human attitudes

113:52toward other humans into a sort of two-dimensional,

113:56two-dimensional scheme.

113:59And one dimension is about ability.

114:03How able, how capable is this other person?

114:08But the other dimension is warmth.

114:12So you can imagine another person

114:15who's very skilled and capable, but is very cold.

114:18And you wouldn't really highly,

114:23you might have some reservations

114:24about that other person.

114:26But there's also a kind of reservation

114:30that we might have about another person

114:31who elicits in us or displays a lot of human warmth,

114:35but is not good at getting things done.

114:38We reserve our greatest esteem, really,

114:45for people who are both highly capable

114:47and also quite warm.

114:50That's like the best of the best.

114:53This isn't a normative statement I'm making.

114:57This is just an empirical statement.

114:59This is what humans seem.

115:01These are the two dimensions that people seem

115:02to kind of like, along which people size other people up.

115:06And in AI research, we really focus on this capability thing.

115:10We want our agents to be able to do stuff.

115:12This thing can play Go at a superhuman level.

115:14That's awesome.

115:16But that's only one dimension.

115:17What about the other dimension?

115:19What would it mean for an AI system to be warm?

115:23And I don't know, maybe there are easy solutions here.

115:26Like we can put a face on our AI systems.

115:29It's cute, it has big ears.

115:31I mean, that's probably part of it.

115:33But I think it also has to do with a pattern of behavior,

115:36a pattern of, what would it mean for an AI system

115:40to display caring, compassionate behavior

115:43in a way that actually made us feel like it was for real?

115:47That we didn't feel like it was simulated.

115:49We didn't feel like we were being duped.

115:51To me, people talk about the Turing test

115:55or some descendant of it.

115:57I feel like that's the ultimate Turing test.

116:01Is there an AI system that can not only convince us

116:05that it knows how to reason

116:07and it knows how to interpret language,

116:09but that we're comfortable saying,

116:12yeah, that AI system's a good guy.

116:14- On the warmth scale, whatever warmth is,

116:18we kind of intuitively understand it,

116:20but we also wanna be able to, yeah,

116:25we don't understand it explicitly enough yet

116:29to be able to engineer it.

116:30- Exactly.

116:32- And that's an open scientific question.

116:33You kind of alluded to it several times

116:35in the human-AI interaction.

116:37That's a question that should be studied

116:38and probably one of the most important questions

116:42as we move to AGI.

116:43- We humans are so good at it.

116:45- Yeah, weird.

116:47- It's not just that we're born warm.

116:50I suppose some people are warmer than others

116:53given whatever genes they manage to inherit.

116:55But there are also learned skills involved.

117:01There are ways of communicating to other people

117:04that you care, that they matter to you,

117:07that you're enjoying interacting with them.

117:09And we learn these skills from one another.

117:14And it's not out of the question

117:16that we could build engineered systems.

117:20I think it's hopeless, as you say,

117:21that we could somehow hand design

117:23these sorts of behaviors.

117:26But it's not out of the question

117:27that we could build systems

117:28that kind of we instill in them

117:32something that sets them out in the right direction

117:36so that they end up learning

117:39what it is to interact with humans

117:40in a way that's gratifying to humans.

117:44I mean, honestly, if that's not where we're headed,

117:47I want out.

117:50(laughing)

117:52- I think it's exciting as a scientific problem,

117:54just as you described.

117:56I honestly don't see a better way to end it

117:59than talking about warmth and love.

118:01And Matt, I don't think I've ever had

118:04such a wonderful conversation

118:06where my questions were so bad

118:07and your answers were so beautiful.

118:09So I deeply appreciate it.

118:10I really enjoyed it.

118:11- Well, it's been very fun.

118:13As you can probably tell,

118:14there's something I like about

118:18kind of thinking outside the box.

118:21So it's good having the opportunity to do that.

118:22- Awesome.

118:23Thanks so much for doing it.

118:25Thanks for listening to this conversation

118:27with Matt Boppenegg.

§13Transcript · 1:58:28–2:00:25

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118:36Please consider supporting this podcast

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118:48Click the links, buy all the stuff.

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118:52and the journey I'm on in my research

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118:57If you enjoy this thing, subscribe on YouTube,

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119:02support it on Patreon, follow on Spotify

119:05or connect with me on Twitter @LexFriedman.

119:08Again, spelled miraculously without the E,

119:12just F-R-I-D-M-A-N.

119:15And now let me leave you with some words

119:17from urologist B.S. Samachandran.

119:20How can a three pound mass of jelly

119:23that you can hold in your palm

119:25imagine angels, contemplate the meaning of infinity

119:28and even question its own place in the cosmos?

119:31Especially awe-inspiring is the fact that any single brain,

119:35including yours, is made up of atoms

119:38that were forged in the hearts of countless

119:41far-flung stars billions of years ago.

119:45These particles drifted for eons and light years

119:48until gravity and change brought them together here now.

119:53These atoms now form a conglomerate, your brain,

119:57that can not only ponder the very stars that gave it birth,

120:00but can also think about its own ability to think

120:04and wonder about its own ability to wander.

120:07With the arrival of humans, it has been said,

120:10the universe has suddenly become conscious of itself.

120:14This truly is the greatest mystery of all.

120:19Thank you for listening and hope to see you next time.

120:23(upbeat music)

120:25(upbeat music)

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