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LIVE EVENT Q&A: Dr. Andrew Huberman at The Wiltern in Los Angeles

Episode 2022-11-092022-11-09EnglishMembers only
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§01Why a live Q&A became an episode

This episode is the recorded question-and-answer portion of a live Huberman Lab Podcast event, held at the Wiltern Theater in Los Angeles and titled The Brain Body Contract. The host explains that the evening had two parts. The first was a lecture on science and science-based tools for mental health, physical health and performance. The second was an open Q&A. Audience members asked about topics from the podcast, their own interests, things they had picked up on social media, or general questions about mental health, physical health and performance. The recording was released so that people who could not attend could still hear the answers.

Before the questions, the host thanks the event's sponsors. Eight Sleep makes smart mattress covers that can heat and cool. The host says they started sleeping on one about eight months earlier, and reports sleeping more deeply, waking less often during the night (if at all), and waking up feeling better even after the same amount of sleep. They add that they have shipped the cover to places they travel to. The read gives an offer of up to $400 off a SleepFit Holiday Bundle that includes the Pod 3 cover, with shipping to the USA, Canada, the United Kingdom, select EU countries and Australia. The second sponsor is the supplement partner Momentus. It is described as shipping internationally and making single-ingredient formulations that match what the podcast discusses. These are sponsor statements and personal testimony, not evidence presented in the Q&A.

§02ADHD: dopamine thresholds, focus training and where medication fits

The first question asks what happens in the mind and body with ADHD, and whether it can be addressed without medication. The answer starts with framing. ADHD used to be called ADD, and the speaker calls the "hyperactivity" part of the name "a little misleading." They also state plainly, "I'm not a clinician here," and warn that any kind of chemical manipulation will always have side effects.

The main claim is that ADHD is not a simple inability to focus. Children and adults with ADHD are described as having a tremendous capacity to focus on things they like. The example given is vivid:

You take a kid with ADHD who can't focus, and you give them their favorite video game, and they are a laser.

The proposed explanation is that in ADHD, the threshold to access the dopamine system is higher. Dopamine is described as having an "incredible ability" to focus the brain and other parts of the nervous system. The speaker gives no further detail on this mechanism in this passage.

Next, the speaker adds a caveat: people who need medication are not being told to stop taking it. With that stated, they describe focus-training exercises, explored mainly in China and starting to be explored elsewhere, that "do seem to be of benefit." These are literally visual focus exercises, now used in schools in China. The idea behind them is stated directly:

Your mental focus, that is your ability to focus on things cognitively, follows your visual focus.

Stress is described as narrowing this further, putting a person into "a soda straw view of the world." The exercise itself consists of spending one to three minutes trying to hold visual focus on something. The speaker notes that blinking is allowed and that you shouldn't let your eyes dry out. This is said to increase the ability to focus cognitively, and the speaker says simply, "And it works." They also stress that "focusing always involves refocusing." Bringing attention back is part of the practice, not a sign that it has failed.

The second non-prescription tool comes from a data set the speaker credits to Wendy Suzuki's lab at NYU, noting it was "not collected by my lab." They first call the practice roughly 10 minutes a day, then correct this to 13 minutes a day of meditation focused only on breathing. This practice is reported to have improved focus significantly. Asked why it is not better known, the speaker notes that Suzuki is now Dean of Arts and Sciences at NYU, so students are hearing about it. They also acknowledge a limitation: it takes discipline, and very few people keep up a daily meditation of this kind consistently. The segment closes with the line "So say the data."

Supplements are discussed with more caution. The speaker assumes the questioner meant prescription medication when they said "medication," and notes that some supplements increase dopamine, mainly L-tyrosine, which is the precursor to dopamine and so will raise dopamine levels. They also say it is something "to think carefully about before you start tampering with your dopamine system." They recommend an order, which they say they will repeat "as many times as necessary":

Rely on behavioral tools first, where possible. Treat sleep and nutrition as prerequisites for all mental health, physical health and performance; "You simply can't neglect those." Only if all of that isn't working, turn to supplement-based tools or prescription medication.

Within this framework, the speaker still says "it's clear" that prescription drugs such as Vyvanse, Adderall and Ritalin work for ADHD. They note that some people choose "more subtle forms of pharmacologic manipulation like L-tyrosine." The answer therefore offers options and an order for trying them, and it does not reject medication.

§03Space-time bridging as a perceptual exercise

Prompted by an audience mention, the speaker takes up space-time bridging. They say they discussed it long ago and then set it aside because "we wanted more data," and that an upcoming meditation episode will cover it. The description is mainly visual, but the speaker notes that people with low vision or no vision could do it with their hearing instead, translating the exercise to the auditory system.

The first step is to close your eyes and focus on the spot just behind the forehead, sometimes called the third eye center. The speaker gives a neurobiological reason why meditators do this. The brain has no sensory neurons: no touch, no pain, nothing to sense. Focusing on any part of the body or on the breath means perceiving the inner landscape (interoception), and looking out at the world is exteroception. Focusing behind the forehead with eyes closed is, in this account, focusing on your thinking. As supporting illustration, the speaker cites neurosurgeries in which surgeons work inside the brain while the patient plays a violin, with no anesthetic required.

It's the one place to focus your attention for which you abandon sensation.

In a brief aside, the speaker criticizes how both traditional practices and science wrap ideas in complex language. They call it "a separator" that reduces the number of people who could be brought to potentially useful practices. They include themselves among those who sometimes "overuse mechanism" and fancy phrases that hide basic principles, and argue that the simplest language tends to unify people around the practices.

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