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Jamie Metzl: Lab Leak Theory

第247期2021-12-08English

嘉宾:Jamie Metzl

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§01Transcript · 00:00–09:20

00:00The following is a conversation with Jamie Metzl,

00:02author specializing in topics of genetic engineering,

00:05biotechnology, and geopolitics.

00:09In the past two years, he has been outspoken

00:12about the need to investigate and keep an open mind

00:15about the origins of COVID 19.

00:18In particular, he has been keeping an extensive

00:20up to date collection of circumstantial evidence

00:23in support of what is colloquially known

00:25as lab leak hypothesis that COVID 19 leaked in 2019

00:30from the Wuhan Institute of Virology.

00:33In part, I wanted to explore the idea

00:35in response to the thoughtful criticism

00:37to parts of the Francis Collins episode.

00:40I will have more and more difficult conversations like this

00:43with people from all walks of life

00:45and with all kinds of ideas.

00:47I promise to do my best to keep an open mind

00:50and yet to ask hard questions

00:52while together searching for the beautiful

00:54and the inspiring in the mind of the other person.

00:57It's a hard line to walk gracefully,

00:59especially for someone like me,

01:01who's a bit of an awkward introvert

01:03with barely the grasp of the English language

01:06or any language, except maybe Python and C++.

01:10But I hope you stick around, be patient and empathetic

01:13and maybe learn something new together with me.

01:17This is the Lex Friedman podcast.

01:19To support it, please check out our sponsors

01:21in the description.

01:22And now, here's my conversation with Jamie Metzl.

01:27What is the probability in your mind

01:29that COVID 19 leaked from a lab?

01:32In your write up, I believe you said 85%.

01:35I know it's just a percentage.

01:37We can't really be exact with these kinds of things,

01:39but it gives us a sense where your mind is,

01:42where your intuition is.

01:43So as it stands today, what would you say is that probability?

01:46I would stand by what I've been saying

01:48since really the middle of last year.

01:51It's more likely and not, in my opinion,

01:55that the pandemic stems

01:56from an accidental lab incident in Wuhan.

01:59Is it 90%, is it 65%, I mean, that's kind of arbitrary.

02:04But when I stack up all of the available evidence

02:08and all of it on both sides is circumstantial,

02:11it weighs very significantly toward a lab incident origin.

02:14So before we dive into the specifics at a high level,

02:17what types of evidence, what intuition, what ideas

02:22are leading you to have that kind of estimate?

02:25Is it possible to kind of condense,

02:28when you look at the wall of evidence before you,

02:32where's your source, the strongest source of your intuition?

02:36And I would have to say it's just logic

02:39and deductive reasoning.

02:40So before I make the case for why I think

02:42it's most likely a lab incident origin,

02:44let's just say why it could be,

02:46and still could be a natural origin.

02:49All of this is a natural origin in the sense

02:51that it's a bat virus backbone, horseshoe bat virus backbone.

02:56Okay, I'm gonna keep pausing you to define stuff.

03:00So maybe it's useful to say, what do we mean by lab leak?

03:04What do we mean by natural origin?

03:05What do we mean by virus backbone?

03:07Okay, great questions.

03:09So viruses come from somewhere.

03:11Viruses have been around for 3.5 billion years,

03:14and they've been around for such a long time

03:17because they are adaptive and they're growing

03:20and they're always changing and they're morphing.

03:23And that's why viruses are,

03:26I mean, they've been very successful and we are our victims.

03:29Sometimes we're beneficiaries.

03:30We have viral DNA has morphed into our genomes,

03:34but now it's certainly in the case of COVID 19,

03:37we are victims of the success of viruses.

03:42And so when we talk about a backbone,

03:44so the SARS CoV2 virus, it has a history

03:50and these viruses don't come out of whole cloth.

03:52There are viruses that morph.

03:54And so we know that at some period,

03:59maybe 20 years ago or whatever,

04:02the virus that is SARS CoV2 existed in horseshoe bats.

04:08It was a horseshoe bat virus and it evolved somewhere.

04:13And there are some people who say,

04:15there's no evidence of this,

04:16but it's a plausible theory

04:18based on how things have happened in the past.

04:21Maybe that virus jumped from the horseshoe bat

04:25through some intermediate species.

04:27So it's like, let's say there's a bat

04:29and that it infects some other animal.

04:31Let's say it's a pig or a raccoon dog or a civet cat.

04:36They're all pangolin.

04:37They're all sorts of animals that have been considered.

04:40And then that virus adapts into that new host

04:43and it changes and grows.

04:45And then according to the quote unquote

04:48natural origins hypothesis,

04:49it jumps from that animal into humans.

04:53And so what you could imagine

04:55and some of the people who are making the case,

04:57all of the people actually,

04:57who are making the case for a natural origin of the virus,

05:00what they're saying is it went from bat

05:03to some intermediate species.

05:05And then from that intermediate species, most likely,

05:08there's some people who say it went directly bat to human,

05:10but through some intermediate species.

05:13And then humans interacted with that species.

05:16And then it jumped from that, whatever it is to humans.

05:20And that's a very plausible theory.

05:21It's just that there's no evidence for it.

05:23And the nature of the interaction is,

05:25do most people kind of suggest this at the wet markets?

05:29So the interaction of the humans with the animal

05:32is in the form of it's either a live animal

05:35as being sold to be eaten or a recently live animal,

05:39but newly dead animal being sold to be eaten.

05:41That's certainly one very possible possibility,

05:46a possible possibility, I don't know if that's a word.

05:48But the people who believe in the wet market origin,

05:52that's what they're saying.

05:52So they had one of these animals,

05:55they were cutting it up, let's say, in a market

05:57and maybe some of the blood got into somebody's,

06:01maybe had a cut on their hand or maybe it was aerosolized

06:04and so somebody breathed it.

06:05And then that virus found this new host

06:09and that was the human host.

06:11But you could also have that happen in, let's say, a farm.

06:14So it's happened in the past that let's say

06:17that there are farms and because of human encroachment

06:21into wild spaces, we're pushing our farms

06:24and our animal farms further and further

06:27into what used to be just natural habitats.

06:30And so it's happened in the past, for example,

06:33that there were bats roosting over pig pens

06:35and the bat droppings went into the pig pens.

06:38The viruses in those droppings infected the pigs

06:43and then the pigs infected the humans.

06:45And that's why it's a plausible theory.

06:48It's just that there's basically no evidence for it.

06:51If it was the case that SARS CoV2 comes from this type

06:56of interaction, as in most of the at least recent

07:00past outbreaks, we'd see evidence of that.

07:03Viruses are messy.

07:05They're constantly undergoing Darwinian evolution

07:07and they're changing and it's not that they're just ready

07:10for prime time, ready to infect humans on day one.

07:13Normally you can trace the viral evolution prior

07:18to the time when it infects humans.

07:20But for SARS CoV2, it just showed up on the scene

07:24ready to infect humans.

07:26And there's no history that anybody has found so far

07:30of that kind of viral evolution.

07:33With the first SARS, you could track it

07:35by the genome sequencing that it was experimenting.

07:39And SARS CoV2 was very, very stable,

07:44meaning it had already adapted to humans

07:47by the time it interacted with us.

07:49It's fully adapted.

07:50So with SARS, there's a rapid evolution

07:55when it first kind of hooks onto a human.

07:58Yeah, because it's trying.

07:59Like a virus, its goal is to survive and replicate.

08:02Yeah, no, it's true.

08:03It's like, oh, we're gonna try this.

08:04Oh, that didn't work.

08:05We'll try it exactly like a startup.

08:08And so we don't see that.

08:10And so there are some people who say,

08:11well, one hypothesis is you have a totally isolated

08:16group of humans, maybe in Southern China,

08:18which is more than a thousand miles away from Wuhan.

08:22And maybe they're doing their animal farming

08:26right next to these areas where there are these horseshoe bats.

08:31And maybe in this totally isolated place

08:34that no one's ever heard of,

08:35they're not connected to any other place,

08:37one person gets infected.

08:40And it doesn't spread to anybody else

08:42because they're so isolated.

08:44They're like, I don't know.

08:45I can't even imagine that this is the case.

08:48Then somebody gets in a car and drives all night,

08:52more than a thousand miles through crappy roads

08:55to get to Wuhan, doesn't stop for anything,

08:57doesn't infect anybody on the way.

08:59No one else in that person's village infects anyone.

09:01And then that person goes straight

09:03to the Huanan seafood market,

09:05according to this, in my mind, not very credible theory,

09:09and then unloads his stuff and everybody gets infected.

09:12And they're only delivering those animals

09:15to the Wuhan market, which doesn't even sell very many

09:18of these kinds of animals

§02Transcript · 09:20–19:07

09:20that are likely intermediate species and not anywhere else.

09:23So that's, I mean, it's a little bit of a straw man,

09:26but on top of that, the Chinese have sequenced

09:29more than 80,000 animal samples,

09:32and there's no evidence of this type of viral evolution

09:36that we would otherwise expect.

09:37Let's try to, at this moment, steel man the argument

09:43for the natural origin of the virus.

09:46So just to clarify, so Wuhan is actually,

09:50despite what it might sound like to people,

09:52is a pretty big city.

09:53There's a lot of people that live in it.

09:5511 million.

09:55So not only is there, at the Wuhan Institute of Virology,

09:59there's other centers that do work on viruses,

10:03but there's also a giant number of markets.

10:06And everything we're talking about here

10:08is pretty close together.

10:09So when I kind of look at the geography of this,

10:13I think when you zoom out, it's all Wuhan,

10:16but when you zoom in,

10:17there's just a lot of interesting dynamics

10:19that could be happening and what the cases are popping up

10:21and what's being reported, all that kind of stuff.

10:24So I think the people that argue for the natural origin,

10:29and there's a few recent papers

10:31that come out arguing this,

10:33it's kind of fascinating to watch this whole thing,

10:35but I think what they're arguing

10:36is that there's this Hunan market

10:39that's one of the major markets, the wet markets in Wuhan,

10:45that there's a bunch of cases

10:49that were reported from there.

10:52So if I look at, for example,

10:54the Michael Warby perspective that he wrote in Science,

10:58he argues, he wrote this a few days ago,

11:01the predominance of early COVID cases linked to Hunan market,

11:06and this can't be dismissed as ascertainment bias,

11:09which I think is what people argue,

11:11that you're just kind of focusing on this region

11:13because a lot of cases came,

11:14but there could be a huge number of other cases.

11:18So people who argue against this

11:19say that this is a later stage already.

11:24So he says no, he says this is the epicenter,

11:29and this is a clear evidence, circumstantial evidence,

11:36but evidence nevertheless

11:37that this is where the jump happened to humans,

11:42the big explosion, maybe not case zero,

11:44I don't know if he argues that, but the early cases.

11:47So what do you make of this whole idea?

11:49Can you steel man it before we talk about the alternative?

11:52And my goal here isn't to attack people on the other side,

11:56and my feeling is if there is evidence that's presented

12:00that should change my view,

12:02I hope that I'll be open minded enough to change my view.

12:06And certainly Michael Warby is a thoughtful person,

12:09a respected scientist,

12:11and I think this work is contributive work,

12:14but I just don't think that it's as significant

12:19as has been reported in the press.

12:22And so what his argument is,

12:24is that there is an early cluster in December of 2019

12:30around the Huanan seafood market.

12:33And even though he himself argues

12:36that the original breakthrough case,

12:39the original case, the index case

12:41where the first person infected happened earlier,

12:46happened in October or November, so not in December.

12:49His argument is, well, what are the odds

12:52that you would have this number, this cluster of cases

12:56in the Huanan seafood market,

12:58and if the origin happened someplace else,

13:00wouldn't you expect other clusters?

13:03And it's not an entirely implausible argument,

13:06but there are reasons why I think

13:08that this is not nearly as determinative

13:11as has been reported.

13:12And I certainly had a lot of,

13:14I and others had tweeted a lot about this.

13:17And that is first, the people who were infected

13:21in this cluster, it's not the earliest known virus

13:26of the SARS CoV2, it began mutating.

13:28So this is, it's not the original SARS CoV2 there.

13:31So it had to have happened someplace else.

13:34Two, the people who were infected in the market

13:38weren't infected in the part of the market

13:41where they had these kinds of animals

13:43that are considered to be candidates

13:46as an intermediary species.

13:49And third, there was a bias,

13:51and actually I'll have four things.

13:53Third, there was a bias in the early assessment in China

13:58of what they were looking for.

13:59They were asked, did you have exposure to the market?

14:02Because I think in the early days

14:03when people were figuring things out,

14:05that was one of the questions that was asked.

14:08And fourth, and probably most significantly,

14:11we have so little information

14:14about those early cases in China,

14:16and that's really unfortunate.

14:18I know we'll talk about this later

14:19because the Chinese government is preventing access

14:23to all of that information, which they have,

14:26which could easily help us get to the bottom,

14:28at least know a ton more about how this pandemic started.

14:31And so this is, it's like grasping at straws

14:36in the dark with gloves on.

14:38That's right.

14:39But to steel man the argument,

14:41we have this evidence from this market,

14:45and yes, the Chinese government

14:47has turned off the lights essentially,

14:48so we have very little data to work with,

14:51but this is the data we have.

14:53So who's to say that this data

14:55doesn't represent a much bigger data set

14:58that a lot of people got infected at this market

15:01where even at the parts, or especially at the parts

15:04where the infected meat was being sold?

15:09So that could be true, and it probably is true.

15:13The question is, is this the source?

15:16Is this the place where this began?

15:18Or was this just a place where it was amplified?

15:22And I certainly think that it's extremely likely

15:26that the Huanan seafood market was a point of amplification.

15:31And it's just answering a different question.

15:33Basically what you're saying is it's very difficult

15:35to use the market as evidence for anything

15:38because it's probably not even the starting point.

15:42So it's just a good place for it to continue spreading.

15:45That's certainly my view.

15:47What Michael Warby's argument is, Marco, is that,

15:51well, what are the odds of that?

15:53That we're seeing this amplification in the market.

15:57And if we, let me put it this way.

16:00If we had all of the information,

16:02if the Chinese government hadn't blocked access

16:06to all of this, because there's blood bank information,

16:08there's all sorts of information,

16:10and based on a full and complete understanding,

16:14we came to believe that all of the early cases

16:18were at this market.

16:19I think that would be a stronger argument

16:22than what this is so far.

16:23But everything leads to the fact that why is it

16:26that the Chinese government,

16:28which was, frankly, after a slow start,

16:31the gold standard of doing viral tracking for SARS 1,

16:36why have they apparently done so little

16:39and shared so little?

16:41I think it asks, it begs a lot of questions.

16:45Okay, so let's then talk about the Chinese government.

16:50There's several governments, right?

16:51So one is the local government of Wuhan.

16:55And not just the Chinese government.

16:56Let's talk about government.

16:59No, let's talk about human nature.

17:02Let's just keep zooming out.

17:03Let's talk about planet Earth.

17:04No, so there's the Wuhan local government.

17:08There's the Chinese government led by Xi Jinping.

17:13And there's governments in general.

17:16I'm trying to empathize.

17:18So my father was involved with Chernobyl.

17:21I'm trying to put myself into the mind of local officials,

17:25of people who are like,

17:27oh shit, there's a potential catastrophic event

17:32happening here and it's my ass

17:36because there's incompetence all over the place.

17:39Yeah, human nature is such that there's incompetence

17:41all over the place and you're always trying to cover it up.

17:44And so given that context,

17:48I want to lay out all the possible incompetence,

17:52all the possible malevolence,

17:54all the possible geopolitical tensions here.

18:01All right, where in your sense did the coverup start?

18:06So there's this suspicious fact,

18:13it seems like that the Wuhan Institute of Virology

18:16had a public database of thousands

18:19of sampled bad coronavirus sequences

18:22and that went offline in September of 2019.

18:26What's that about?

18:28So let me talk about that specific

18:30and then I'll also follow your path of zooming out

18:33and it's a really important.

18:34Is that a good starting point?

18:35It's a great starting point, yeah, yeah.

18:37So but there's a bigger story

18:40but let me talk about that.

18:42So the Wuhan Institute of Virology

18:46and we can go into the whole history

18:48of the Wuhan Institute of Virology either now or later

18:50because I think it's very relevant to the story

18:52but let's focus for now on this database.

18:55They had a database of 22,000 viral samples

19:00and sequence information about viruses

19:02that they had collected.

19:05Some of which, the collection of some of which

§03Transcript · 19:07–28:33

19:07was supported through funding from the NIH,

19:10not a huge NIH through the EcoHealth Alliance.

19:12It's a relatively small amount, $600,000 but not nothing.

19:18The goal of this database

19:20was so that we could understand viral evolution

19:24so that exactly for this kind of moment

19:27where we had an unknown virus,

19:29we could say, well, is this like anything

19:31that we've seen before?

19:33And that would help us both understand what we're facing

19:35and be better able to respond.

19:39So this was a password protected public access database.

19:45In 2019, in September 2019,

19:50it became inaccessible and then the whole,

19:52a few months later, the entire database disappeared.

19:55What the Chinese have said is that because there were

20:00all kinds of computer attacks on this database

20:03but why would that happen in September 2019

20:07before the pandemic, at least as far as we know.

20:11So just to clarify.

20:13Yes.

20:14It went down to September 2019

20:17just so we get the year straight.

20:19January 2020 is when the virus

20:22really started getting the press.

20:25So we're talking about December 2019,

20:29a lot of early infections happened.

20:30September 2019 is when this database goes down.

20:34Just to clarify because you said it quickly,

20:37the Chinese government said

20:39that their database was getting hacked.

20:44Therefore, Xu Zhengli, the director of this part

20:48of the Wuhan Institute of Virology said that.

20:50Oh really, she was the one that said it?

20:53She was the one who said it.

20:54Oh boy, I did not even know that part.

20:56Yeah.

20:57Well, she's an interesting character.

20:58We'll talk about her.

20:59Yeah.

21:00So the excuse is that it's getting cyber attacked a lot

21:07so we're gonna take it down without any further explanation

21:10which seems very suspicious.

21:12And then this virus starts to emerge

21:15in October, November, December.

21:17There's a lot of argument about that, but after.

21:19Sorry to interrupt, but some people are saying

21:21that the first outbreak could have happened

21:23as early as September.

21:25I think it's more likely it's October, November,

21:27but for the people who are saying that the first outbreak,

21:31the first incident of a known outbreak,

21:34at least to somebody, happened in September,

21:37they make the argument, well, what if that also happened

21:40in mid September of 2019?

21:42I'm not prepared to go there,

21:43but there are some people who make that argument.

21:45But I think, again, if I were to put myself

21:47in the mind of officials,

21:50whether it's officials within the Wuhan Institute of Virology

21:53or Wuhan local officials,

21:58I think if I notice some major problem,

22:02like somebody got sick,

22:04some sign of, oh shit, we screwed up,

22:09that's when you kind of do the slow,

22:11there's like a Homer Simpson meme

22:13where you slowly start backing out,

22:15and I would probably start hiding stuff.

22:20CYA, yeah.

22:21Yeah, and then coming up with really shady excuses.

22:25It's like you're in a relationship

22:27and your girlfriend wants to see your phone,

22:30and you're like, I'm sorry,

22:31I'm just getting attacked by the Russians now.

22:33The cyber security issue, I can't.

22:35Yeah, I wish I could.

22:36I wish I could, it's just unsafe right now.

22:39So would it be okay if I give you my kind of macro view

22:42of the whole information space

22:44and why I believe this has been so contentious?

22:50If I had to give my best guess,

22:52and I underline the word guess of what happened,

22:56and your background, your family background with Chernobyl

22:59I think is highly relevant here.

23:02So after the first SARS, there was a recognition

23:06that we needed to distribute knowledge about virology

23:09and epidemiology around the world,

23:11that people in China and Africa and Southeast Asia,

23:14they were the frontline workers,

23:16and they needed to be doing a lot of the viral monitoring

23:20and assessment so that we could have an early alarm system.

23:25And that was why there was a lot of investment

23:28in all of those places in building capacity

23:30and training people

23:31and helping to build institutional capacity.

23:34And the Chinese government,

23:36they recognized that they needed to ramp things up.

23:40And then the World Health Organization

23:43and the World Health Assembly,

23:44they had their international health regulations

23:47that were designed to create a stronger infrastructure.

23:50So that was the goal.

23:52There were a lot of investments,

23:54and I know we'll talk later

23:55about the Wuhan Institute of Virology,

23:56and I won't go into that right now.

23:59So there was all of this distributed capacity.

24:02And so in the early days, there's a breakout in Wuhan.

24:07We don't know, is it September, October, November?

24:10Maybe December is when the local authorities

24:14start to recognize that something's happening.

24:16But at some point in late 2019,

24:19local officials in Wuhan understand that something is up.

24:23And exactly like in Chernobyl,

24:26these guys exist within a hierarchical system,

24:29and they are going to be rewarded if good things happen,

24:32and they're going to be in big trouble

24:34if bad things happen under their watch.

24:36So their initial instinct is to squash it.

24:39And my guess is they think,

24:42well, if we squash this information,

24:44we can most likely beat back this outbreak,

24:47because lots of outbreaks happen all the time,

24:49including of SARS 1,

24:51where there was multiple lab incidents

24:53out of a lab in Beijing.

24:56And so they start their coverup on day one.

24:59They start screening social media.

25:02They send nasty letters to different doctors

25:06and others who are starting to speak up.

25:08But then it becomes clear that there's a bigger issue.

25:12And then the national government of China,

25:14again, this is just a hypothesis,

25:17the national government gets involved.

25:19They say, all right, this is getting much bigger.

25:21They go in and they realize

25:24that we have a big problem on our hands.

25:26They relatively quickly know

25:28that it's spreading human to human.

25:30And so the right thing for them to do then

25:32is what the South African government is doing now

25:35is to say, we have this outbreak.

25:37We don't know everything, but we know it's serious.

25:40We need help.

25:41But that's not the instinct of people in most governments

25:44and certainly not in authoritarian governments like China.

25:48And so the national government,

25:50they have a choice at that point.

25:52They can do option one,

25:55which is what we would hear called the right thing,

25:57which is total transparency.

25:59They criticize the local officials for having this coverup.

26:03And they say, now we're going to be totally transparent.

26:05But what does that do in a system

26:07like the former Soviet Union, like China now?

26:10If local officials say, wait a second,

26:12I thought my job was to cover everything up,

26:15to support this alternative reality

26:18that authoritarian systems need in order to survive.

26:22Well, now I'm gonna be held accountable

26:23for if I'm not totally transparent,

26:26like your whole system would collapse.

26:29So the national government, they have that choice

26:32and their only choice according to the logic of their system

26:37is to be all in on a coverup.

26:39And that's why they block the World Health Organization

26:41from sending its team to Wuhan for over three weeks.

26:45They overtly lie to the World Health Organization

26:48about human to human transmission.

26:51And then they begin their coverups.

26:53So they begin very, very quickly destroying samples,

26:56hiding records, they start imprisoning people

26:59for asking basic questions.

27:02Soon after they establish a gag order,

27:05preventing Chinese scientists from writing

27:08or saying anything about pandemic origins

27:10without prior government approval.

27:12And what that does means that there isn't a lot of data,

27:16there's not nearly enough data coming out of China.

27:19And so lots of responsible scientists outside of China

27:22who are data driven say, well,

27:25I don't have enough information to draw conclusions.

27:29And then into that vacuum step a relatively small number

27:35of largely virologists, but also others,

27:39respected scientists.

27:40And I know we'll talk about the, I think,

27:43infamous Peter Daszak who say,

27:47well, without any real foundation in the evidence,

27:52they say, we know pretty much this comes from nature

27:56and anyone who's raising the possibility

28:00of a lab incident origin is a conspiracy theorist.

28:03So that message starts to percolate.

28:07And then in the United States, we have Donald Trump

28:11and he's starting to get criticized for America's failure

28:15to respond, prepare for and respond adequately

28:17to the outbreak.

28:19And so he starts saying, well, I know first

28:22after praising Xi Jinping, he starts saying,

28:25well, I know that China did it and the WHO did it

28:28and he's kind of pointing fingers at everybody but himself.

§04Transcript · 28:33–38:07

28:33And then we have a media here that had shifted

28:36from the traditional model of he said, she said journalism,

28:40so and so said X and so and so said Y

28:43and then we'll present both of those views.

28:45With Donald Trump,

28:47he would make outlandish starting positions.

28:50So he would say, Lex is an ax murderer.

28:53And then in the early days, they would say,

28:55Lex is an ax murderer, Lex's friend says

28:59he's not an ax murderer and we have a four day debate,

29:01is he or isn't he?

29:02And then at day four, someone would say,

29:04why are we having this debate at all?

29:06Because the original point is just is baseless.

29:11And so the media just got in the habit,

29:13here's what Trump said and here's why it's wrong.

29:16It's very complicated to figure out

29:20what is the role of a politician?

29:21What is the role of a leader in this kind of game

29:23of politics?

29:25But certainly in when there's a tragedy,

29:29when there's a catastrophic event,

29:32what it takes to be a leader is to see clearly

29:35through the fog and to make big bold decisions

29:38that does speak to the truth of things.

29:41And even if it's unpopular truth,

29:44to listen to the people, to listen to all sides,

29:48to the opinions, to the controversial ideas

29:51and to see past all the bullshit,

29:54all the political bullshit and just speak to the people,

29:59speak to the world and make bold, big decisions.

30:02That's probably what was needed in terms of leadership.

30:04And I'm not so willing to criticize whether it's Joe Biden

30:09or Donald Trump on this.

30:11I think most people cannot be great leaders,

30:15but that's why when great leaders step up,

30:18we write books about them.

30:20And I agree.

30:21And even though, I mean, I think of myself

30:24as a progressive person, I certainly was a critic

30:27of a lot of what President Trump did.

30:33But on this particular case,

30:36even though he may have said it in an uncouth way,

30:39Donald Trump was actually, in my view, right.

30:43I mean, when he said, hey, let's look at this lab.

30:46I mean, he said, I have evidence, I can't tell you.

30:48I don't think he even had the evidence.

30:51But his intuition that this probably comes from a lab,

30:55in my view was a correct intuition.

30:58And certainly I started speaking up

31:00about pandemic origins early in 2019.

31:04And my friends, my democratic friends were brutal with me

31:08saying, what are you doing?

31:09You're supporting Trump in an election year.

31:11And I said, just because Donald Trump is saying something

31:15doesn't mean that I need to oppose it.

31:17If Donald Trump says something that I think is correct,

31:21well, I wanna say it's correct,

31:22just as if he says something that I don't like,

31:25I'm gonna speak up about that.

31:26Good, you walked through the fire.

31:28So that's, you laid out the story here.

31:31And I think in many ways it's a human story.

31:36It's a story of politics, it's a story of human nature.

31:40But let's talk about the story of the virus.

31:45And let's talk about the Wuhan Institute of Virology.

31:48So maybe this is a good time to try to talk about

31:51its history, about its origins,

31:53about what kind of stuff it works on,

31:55about biosafety levels, and about Batwoman.

32:00Yeah, Xu Zhengli, yes.

32:02Xu Zhengli.

32:03So what is the Wuhan Institute of Virology,

32:06when did it start?

32:07Yeah, so it's a great question.

32:09So after SARS 1, which was in the early 2000, 2003, 2004,

32:15there was this effort to enhance,

32:20as I mentioned before, global capacity, including in China.

32:23So the Wuhan Institute of Virology

32:25had been around for decades before then.

32:29But there was an agreement between the French

32:32and the Chinese governments to build the largest BSL4 lab,

32:37BSL4 lab, so biosafety level four.

32:39So in these what are called high containment labs,

32:42there's level four, which is the highest level.

32:44And people have seen that on TV and elsewhere,

32:47where you have the people in the different suits

32:50and all of these protections.

32:51And then there's level three, which is still very serious,

32:56but not as much as level four.

32:58And then level two is just kind of goggles and some gloves

33:03and maybe a face mask, much less.

33:05So the French and the Chinese governments agreed

33:10that France would help build the first

33:13and still the largest BSL4 plus some mobile BSL3 labs.

33:20And they were going to do it in Wuhan.

33:22And Wuhan is kind of like China's Chicago.

33:24And I had actually been, it's a different story.

33:26I'd been in Wuhan relatively not that long

33:30before the pandemic broke out.

33:32And that was why I knew that Wuhan,

33:34it's not some backwater where there are a bunch of yokels

33:37eating bats for dinner every night.

33:40This is a really sophisticated, wealthy, highly educated

33:44and cultured city.

33:45And so I knew that it wasn't like

33:48that even the one on seafood market

33:50wasn't like some of these seafood markets

33:52that they have in Southern China or in Cambodia,

33:55where I lived for two years.

33:57I mean, it was a totally different thing.

33:59I'm gonna have to talk to you about some of the,

34:01including the Wuhan market,

34:02just some of the wild food going on here.

34:04Because you've traveled that part of the world.

34:06But let's not get there.

34:07Let's not get distracted.

34:08Good, as I was telling you, Lex, before,

34:11and this is maybe an advertisement,

34:13is having now listened to a number of your podcasts

34:18when I'm doing long ultra training runs

34:20or driving in the mountains.

34:22Like the really, because in the beginning,

34:23we have to talk about whatever it is is the topic.

34:26But the really good stuff happens later.

34:28So stay tuned. So friends,

34:29you should listen to the end.

34:31I have to say, as I was telling you before,

34:34like when I heard your long podcast with Jérôme Lanier

34:37and he talked about his mother at the very end,

34:41I mean, just beautiful stuff.

34:42So I don't know whether I can match beautiful stuff,

34:45but I'm gonna do my best.

34:47You're gonna have to find out.

34:49Exactly, stay tuned.

34:52So France had this agreement

34:54that they were going to help design and help build

34:57this BSL4 lab in Wuhan.

35:01And it was going to be with French standards,

35:04and there were going to be 50 French experts

35:07who were going to work there

35:09and supervise the work that happened

35:12even after the Wuhan Institute of Virology

35:16in the new location started operating.

35:22But then when they started building it,

35:24the French contractors, the French overseers

35:28were increasingly appalled

35:31that they had less and less control,

35:33that the Chinese contractors were swapping out new things,

35:37it wasn't built up to French standards,

35:39so much that at the end, when it was finally built,

35:44the person who was the vice chairman of the project

35:47and a leading French industrialist named Marieau

35:51refused to sign off.

35:52And he said, we can't support,

35:55we have no idea what this is,

35:58whether it's safe or not.

36:00And when this lab opened,

36:02remember it was supposed to have 50 French experts,

36:05it had one French expert.

36:07And so the French were really disgusted.

36:11And actually when the Wuhan Institute of Virology

36:14and its new location opened in 2018, two things happened.

36:19One, French intelligence privately approached

36:22US intelligence saying, we have a lot of concerns

36:25about the Wuhan Institute of Virology,

36:27about its safety, and we don't even know

36:29who's operating there,

36:30is it being used as a dual use facility?

36:34And also in 2018, the US embassy in Beijing

36:38sent some people down to Wuhan to go and look at,

36:42well, at this laboratory.

36:44And they wrote a scathing cable that Josh Rogin

36:48from the Washington Post later got his hands on saying,

36:52this is really unsafe,

36:54they're doing work on dangerous bat coronaviruses

36:58in conditions where a leak is possible.

37:02And so then you mentioned Shujing Li,

37:05and I'll connect that to these virologists

37:08who I was talking about.

37:11So there's a very credible thesis

37:14that because these pathogenic outbreaks happen

37:17in other parts of the world,

37:19having partnerships with experts in those parts of the world

37:24must be a foundation of our efforts.

37:28We can't just bring everything home

37:29because we know that viruses don't care about borders

37:32and boundaries, and so if something happens there,

37:34it's going to come here.

37:36So very correctly, we have all kinds of partnerships

37:41with experts in these labs,

37:43and Shujing Li was one of those partners.

37:47And her closest relationship was with Peter Daszak,

37:51who's a British, I think now American,

37:53but the president of a thing called EcoHealth Alliance,

37:57which was getting money from NIH.

37:59And basically, EcoHealth Alliance

38:01was a pass through organization.

38:03And over the years, it was only about $600,000.

38:06So almost all of her funding

§05Transcript · 38:07–47:46

38:07came from the Chinese government,

38:09but there's a little bit that came from the United States.

38:11And so she became their kind of leading expert

38:15and the point of contact

38:17between the Wuhan Institute of Virology

38:20and certainly Peter Daszak, but also with others.

38:25And that was why in the earliest days of the outbreak,

38:28I didn't mention that,

38:30I did mention that there were these virologists

38:32who had this fake certainty

38:34that they knew it came from nature

38:36and it didn't come from a lab

38:38and they called people like me conspiracy theorists

38:41just for raising that possibility.

38:43But when Peter Daszak was organizing that effort

38:46in February of 2020,

38:50what he said is we need to rally

38:52behind our Chinese colleagues.

38:54And the basic idea was

38:56these international collaborations are under threat.

38:59And I think it was because of that,

39:01because Peter Daszak's basically his major contribution

39:06as a scientist was just tacking his name

39:09on work that Shujang Li had largely done.

39:12He was defending a lot,

39:14certainly for himself and his organization.

39:16So you think EcoHealth Alliance and Peter

39:20is less about money,

39:21it's more about kind of almost like legacy

39:24because you're so attached to this work?

39:26Is it just on a human level?

39:27I think so.

39:29I mean, I've been criticized for being actually,

39:31I'm certainly a big critic of Peter Daszak,

39:34but I've been criticized by some for being too lenient.

39:38I mean, it's so easy to say,

39:39oh, somebody they're like an evil ogre

39:43and just trying to do evil

39:45and cackling in their closet or whatever.

39:49But I think for most of us,

39:51even those of us who do terrible, horrible things,

39:55the story that we tell ourselves

39:57and we really believe is that we're doing the thing

40:01that we most believe in.

40:02I mean, I did my PhD dissertation

40:04on the Khmer Rouge in Cambodia.

40:06They genuinely saw themselves as idealists.

40:09They thought, well, we need to make radical change

40:13to build a better future.

40:15And what they described as,

40:17that they felt was radical change

40:19was a monstrous atrocities by us.

40:21So the criticism here of Peter

40:26is that he was a part of an organization

40:31that was kind of, well, funding an effort

40:36that was an unsafe implementation

40:39of a biosafety level four laboratory.

40:42Well, a few things.

40:43So what he thought he was doing was,

40:47and then what he thought he was doing

40:49is itself highly controversial

40:51because there's one there that in 2011,

40:56there were, I know you've talked about this

40:57with other guests, but in 2011,

41:00there were the first published papers

41:04on this now infamous gain of function research.

41:07And basically what they did,

41:10both in different labs and certainly in the United States,

41:14in Wisconsin and in the Netherlands,

41:18was they had a bird flu virus

41:21that was very dangerous, but not massively transmissive.

41:28And they had a gain of function process

41:31through what's called serial passage,

41:33which means basically passing advice,

41:35like natural selection, but forcing natural selection

41:39by just passing a virus through different cell cultures

41:42and then selecting for what it is that you want.

41:46So relatively easily, they took this deadly,

41:49but not massively transmissive virus

41:51and turned it into, in a lab,

41:53a deadly and transmissive virus.

41:57And that showed that this is really dangerous.

41:59And so there were, at that point,

42:01there was a huge controversy.

42:03There were some people, like Richard Ebright

42:07and Mark Lipsitch at Harvard,

42:09who were saying that this is really dangerous.

42:12We're in the idea that we need to create monsters

42:16to study monsters.

42:17I think maybe even you have said that in the past.

42:21It doesn't make sense

42:22because there's an unlimited number of monsters.

42:24And so what are we gonna do?

42:25Create an unlimited number of monsters.

42:27And if we do that,

42:28eventually the monsters are going to get out.

42:31Then there was the Peter Daszak camp,

42:33and he got a lot of funding,

42:35particularly from the United States,

42:37who said, well, and certainly Collins and Fauci

42:40were supportive of this.

42:42And they thought, well, there's a safe way

42:44to go out into the world

42:46to collect the world's most dangerous viruses

42:49and to poke and prod them

42:52to figure out how they might mutate,

42:54how they might become more dangerous

42:56with the goal of predicting future pandemics.

43:01And that certainly never happened

43:03with the goal of creating vaccines and treatments.

43:07And that largely never happened,

43:11but that was, so Peter Daszak kind of epitomized

43:14that second approach.

43:18And as you've talked about in the past,

43:20in 2014, there was a funding moratorium

43:24in the United States, and then in 2017, that was lifted.

43:27It didn't affect the funding

43:29that went to the EcoHealth Alliance.

43:33So when this happened in the beginning,

43:37and again, coming back to Peter's motivations,

43:40I don't think, here's the best case scenario for Peter.

43:44I'm gonna give you what I imagine he was thinking,

43:47and then I'll tell you what I actually think.

43:49So I think here's what he's thinking.

43:51This is most likely a natural origin outbreak.

43:56Just like SARS one, again, in Peter's hypothetical mind,

44:00just like SARS one, this is most likely a natural outbreak.

44:04We need to have an international coalition

44:06in order to fight it.

44:08If we allow these political attacks

44:11to undermine our Chinese counterparts

44:14and the trust in these relationships

44:16that we've built over many years,

44:18we're really screwed because they have

44:20the most local knowledge of these outbreaks.

44:23And even though, and this guy gets a lot more complicated,

44:27even though there are basic questions

44:30that anybody would ask and that Shujing Li herself did ask

44:34about the origins of this pandemic,

44:37even though Peter Daszak, and I'll describe this

44:40in a moment, had secret information that we didn't have,

44:44that in my mind massively increases the possibility

44:48of a lab incident origin, I, Peter Daszak,

44:52would like to guide the public conversation

44:55in the direction where I think it should go

44:58and in support of the kind of international collaboration

45:03that I think is necessary.

45:04That's a strong, positive discussion

45:06because it's true that there's a lot of political BS

45:11and a lot of kind of just bickering and lies

45:16as we've talked about.

45:18And so it's very convenient to say, you know what?

45:21Let's just ignore all of these quote unquote lies

45:24and my favorite word, misinformation.

45:27And then because the way out from this serious pandemic

45:31is for us to work together.

45:33So let's strengthen our partnerships

45:36and everything else is just like noise.

45:38Yeah, so let's, and so then now I wanna do

45:41my personal indictment of Peter Daszak

45:43because that's my view, but I wanted to fairly.

45:46That's nice.

45:47Because I think that we all tell ourselves stories

45:51and also when you're a science communicator,

45:56you can't in your public communications

45:59give every doubt that you have or every nuance,

46:03you kind of have to summarize things.

46:05And so I think that he was, again,

46:07in this benign interpretation trying to summarize

46:10in the way that he thought the conversations should go.

46:14Here's my indictment of Peter Daszak.

46:16And I feel like a Brutus here,

46:20but I have not come here to praise Peter Daszak

46:26because while Peter Daszak was doing all of this

46:29and making all of these statements about,

46:31well, we pretty much know it's a natural origin.

46:34Then there was this February, 2020 Lancet letter

46:38where it turns out, and we only knew this later

46:40that he was highly manipulative.

46:42So he was recruiting all of these people.

46:45He drafted the infamous letter calling people like me,

46:48conspiracy theorists.

46:50He then wrote to people like Ralph Barak and Linfa Wang,

46:54who are also very high profile virologists saying,

46:57well, let's not put our names on it.

46:59So it doesn't look like we're doing it,

47:01even though they were doing it.

47:04He didn't disclose a lot of information that they had.

47:09It was a strategic move.

47:10So just in case people are not familiar,

47:13February, 2020, Lancet letter was TLDR,

47:20is a lab leak hypothesis, is a conspiracy theory.

47:24Essentially, yes.

47:26So like with the authority of science,

47:29not saying like it's highly likely,

47:32saying it's obvious, duh, it's natural origin.

47:37Everybody else is just,

47:40everything else is just misinformation.

47:42And look, there's a bunch of really smart people

47:44that signed this, therefore it's true.

§06Transcript · 47:46–57:56

47:46Yeah, not only that, so there were the people

47:49who, 27 people signed that letter.

47:51And then after President Trump cut funding

47:54to EcoHealth Alliance, then he organized 77 Nobel laureates

47:58to have a public letter criticizing that.

48:01But what Peter knew then that we didn't fully know

48:06is that in March of 2018, EcoHealth Alliance,

48:10in partnership with the Wuhan Institute of Virology

48:13and others, had applied for a $14 million grant to DARPA,

48:19which is kind of like the VC side of the venture capital

48:23side of the Defense Department.

48:25They're kind of, where they do kind of big ideas.

48:29By the way, as a tiny tangent,

48:31I've gotten a lot of funding from DARPA.

48:33They fund a lot of excellent robotics research.

48:36And DARPA is incredible.

48:37And among the things that they applied for

48:39is that we, meaning Wuhan Institute of Virology,

48:42is gonna go and it's gonna collect

48:44the most dangerous bat coronaviruses in Southern China.

48:49And then we, as this group,

48:52are going to genetically engineer these viruses

48:56to insert a furin cleavage site.

48:59So I think when everyone's now seen the image

49:02of the SARS CoV2 virus, it has these little spike proteins,

49:06these little things that stick out,

49:07which is why they call it a coronavirus.

49:09Within that spike protein are these furin cleavage sites,

49:12which basically help with the virus

49:14getting access into our cells.

49:18And they were going to genetically engineer

49:20these furin cleavage sites into these bat coronaviruses,

49:24the serbicoviruses.

49:26And then, and so then a year and a half later,

49:30what do we see?

49:31We see a bat coronavirus with a furin cleavage site

49:36unlike anything that we've ever seen before

49:39in that category of SARS like coronaviruses.

49:44That, well, yes, I mean, the DARPA very correctly

49:49didn't support that application.

49:50Well, let's actually, let's like pause on that.

49:53So for a lot of people, that's like the smoking gun.

49:56Okay, let's talk about this 2018 proposal to DARPA.

50:02So I guess who's drafted the proposal?

50:04Is it EcoHealth, but the proposal is to do research.

50:09EcoHealth is technically a US funded organization.

50:14Primarily.

50:15And then the idea was to do work

50:18at Wuhan Institute of Virology.

50:20With, yeah, so it was.

50:22With EcoHealth.

50:23Yes, so EcoHealth, basically the Wuhan Institute of Virology

50:26was gonna go and they were gonna collect these viruses

50:29and store them at Wuhan Institute of Virology.

50:31But they're also gonna do the actual task.

50:33According, it's a really important point.

50:35According to their proposal, the actual work

50:38was going to be done at the lab of Ralph Barak

50:41at the University of North Carolina,

50:43who's probably the world's leading expert on coronaviruses.

50:47And so we know that DARPA didn't fund that work.

50:54We know, I think quite well that Ralph Barak's lab,

50:59in part because it was not funded by DARPA,

51:04they didn't do that specific work.

51:06What we don't know is, well, what work was done

51:10at the Wuhan Institute of Virology

51:12because WIV was part of this proposal.

51:15They had access to all of the plans.

51:18They had done, they had their own capacity

51:21and they had already done a lot of work

51:23in genetically altering this exact category of viruses.

51:28They had created chimeric mixed viruses.

51:33They had mastered pretty much all of the steps

51:37in order to achieve this thing that they applied

51:39for funding with EcoHealth to do.

51:42And so the question is, did the Wuhan Institute of Virology

51:47go through with that research anyway?

51:50And in my mind, that's a very, very real possibility.

51:53It would certainly explain

51:54why they're giving no information.

51:57And as you know, I've been a member

51:59of the World Health Organization Expert Advisory Committee

52:02on Human Genome Editing, which Dr. Tedros created

52:06in the aftermath of the announcement

52:07of the world's first CRISPR babies.

52:10And it was just basically the first time

52:11and it was just basically the exact same story.

52:14So Ho Chiang Kui, a Chinese scientist,

52:16it was not a first tier scientist,

52:18but a perfectly adequate second tier scientist,

52:21came to the United States, learned all of these capacities,

52:23went back to China and said,

52:25well, there's a much more permissive environment.

52:28I'm gonna be a world leader.

52:30I'm gonna establish both myself and China.

52:33So in every scientific field, we're seeing this same thing

52:37where you kind of learn a model and then you do it in China.

52:41So is it possible that the Wuhan Institute of Virology

52:45with this exact game plan was doing it anyway?

52:49Do we, possible?

52:51We have no clue what work was being done

52:55at the Wuhan Institute of Virology.

52:56It seems extremely likely

52:59that at the Wuhan Institute of Virology,

53:02and this is certainly the US government position,

53:04there was the work that was being done in Dr. Hsu's lab,

53:08but that wasn't the whole WIV.

53:10We know, at least according to the United States government,

53:12that there was the Chinese military,

53:14that PLA was doing work there.

53:17Were they doing this kind of work, not to create a bioweapon,

53:22but in order to understand these viruses,

53:25maybe to develop vaccines and treatments?

53:28It seems like a very, very logical possibility.

53:33And then, so we know that the Wuhan Institute of Virology

53:36had all of the skills.

53:37We know that they were part of this proposal.

53:40And then you have Peter Daszak, who knows all of this,

53:43that at that time, in February of 2020, we didn't know.

53:47But then he comes swinging out of the gate,

53:49saying anybody who's raising this possibility

53:52of a lab incident origin is a conspiracy theorist.

53:57I mean, it really makes him look, in my mind,

54:00very, very bad.

54:01And yet, not to at least be somewhat open minded on this,

54:04because he knows all the details.

54:06He knows that it's not 0%.

54:08I mean, there's no way in his mind could you even argue that.

54:12So it's potential because of the bias,

54:14because of your focus.

54:16I mean, it could be the Anthony Fauci masks thing,

54:20whereas he knows there's some significant probability

54:23that this is happening.

54:24But in order to preserve good relations

54:28with our Chinese colleagues,

54:30we want to make sure we tell a certain kind of narrative.

54:33So it's not really lying.

54:34It's doing the best possible action at this time

54:39to help the world.

54:40Not that this already happened.

54:42But that's how like...

54:43I think it's quite likely that that was the story

54:47that he was telling himself.

54:49But it's that lack of transparency, in my mind,

54:55is fraudulent, that we were struggling

54:59to understand something that we didn't understand.

55:02And that I just think that people who possess

55:05that kind of information, especially when the existence,

55:10like the entire career of Peter Daszak

55:12is based on US taxpayers,

55:14there's a debt that comes with that.

55:16And that debt is honesty and transparency.

55:19And for all of us, and you talked about

55:21your girlfriend checking your phone.

55:22For all of us, being honest and transparent

55:26in the most difficult times is really difficult.

55:29If it were easy, everybody would do it.

55:31And I just feel that Peter was the opposite of transparent

55:37and then went on the offensive.

55:39And then had the gall of joining,

55:44I know we can talk about this,

55:46this highly compromised joint study process

55:51with the international experts

55:54and their Chinese government counterparts.

55:56And used that as a way of furthering

55:59this, in my mind, fraudulent narrative

56:05that it almost certainly came from natural origins

56:09and a lab origin was extremely unlikely.

56:12Just to stick briefly on the proposal to wrap that up,

56:15because I do think, in a kind of John Stewart way,

56:22if you heard that a bit yet,

56:25sort of kind of like common sense way,

56:30the 2018 proposal to DARPA from EcoHealth Alliance

56:35and Wuhan Institute of Virology,

56:38just seems like a bit of a smoking gun to me, like that.

56:43So there's this excellent book that people should read

56:46called Viral, The Search for the Origin of COVID 19.

56:50Matt Ridley and Alena Chan, I think Alena is in MIT.

56:54Probably. At the Broad, yeah.

56:55At Broad Institute, yeah, yeah.

56:57So she, I heard her in an interview

57:00give this analogy of unicorns.

57:04And where basically somebody writes a proposal

57:09to add horns to horses, the proposal is rejected.

57:14And then a couple of years later or a year later,

57:17a unicorn shows up.

57:19In the place where they're proposing to do it.

57:23I mean, that's so, I had.

57:24And then everyone's like, it's natural origin.

57:26It's like, it's possible it's natural origin.

57:29Like we haven't detected a unicorn yet.

57:31And this is the first time we've detected a unicorn.

57:33Or it could be this massive organization

57:36that was planning, is fully equipped,

57:39has like a history of being able to do this stuff,

57:42has the world experts to do it, has the funding,

57:45has the motivation to add horns to horses.

57:48And now a unicorn shows up and they're saying, nope.

57:52Definitely natural.

57:54That connects to your first question

§07Transcript · 57:56–1:08:33

57:56of how do I get to my 85%?

57:59And here's a summary of that answer.

58:03And so it's what I said in my 60 Minutes interview

58:06a long time ago, of all the gin joints

58:07and all the towns and all the world,

58:09the quote from Casablanca.

58:11And so of all the places in the world

58:14where we have an outbreak of a SARS like bat coronavirus,

58:19it's not in the area of the natural habitat

58:23of the horseshoe bats.

58:25It's the one city in China

58:28with the first and largest level four virology lab,

58:33which actually wasn't even using it.

58:34They were doing level three and level two for this work,

58:38where they had the world's largest collection

58:39of bat coronaviruses,

58:41where they were doing aggressive experiments

58:45designed to make these scary viruses scarier,

58:49where they had been part of an application

58:52to insert a furin cleavage site,

58:56able to infect human cells.

58:59And when the outbreak happened,

59:02we had a virus that was ready for action to infect humans.

59:07And to this day, better able to infect humans

59:09than any other species, including bats.

59:13And then from day one, there's this massive coverup.

59:17And then on top of that,

59:19in spite of lots of efforts by lots of people,

59:21there's basically no evidence

59:24for the natural origin hypothesis.

59:27Everything that I've described just now is circumstantial,

59:29but there's a certain point

59:31where you add up the circumstances

59:34and you see this seems pretty, pretty likely.

59:37I mean, if we're getting to 100%,

59:39we are not at 100% by any means.

59:42There still is a possibility of a natural origin.

59:45And if we find that, great.

59:46But from everything that I know,

59:48that's how I get to my 85.

59:50And we'll talk about why this matters

59:53in the political sense, in the human sense,

59:56in the science, in the realm of science,

59:59all of those factors.

60:00But first, as Nietzsche said, let us look into the abyss

60:04and the games we'll play with monsters.

60:06That is colloquially called gain of function research.

60:12Let me ask the kind of political sounding question,

60:14which is how people usually phrase it.

60:16Did Anthony Fauci fund gain of function research

60:24at the Wuhan Institute of Virology?

60:26So it depends.

60:27I mean, I've obviously been very closely monitoring this.

60:31I've spoken a lot about it.

60:32I've written about it.

60:34And it depends on, I mean, not to quote Bill Clinton,

60:37but to quote Bill Clinton, it depends on what

60:39the definition of is is.

60:41And so if you use a common sense definition of gain of function,

60:46and by gain of function, there are lots of things

60:48like gene therapies that are gain of function.

60:50But here, what we mean is gain of function

60:52for pathogens potentially able to create human pandemics.

61:00But if you use the kind of common sense language,

61:04well, then he probably did.

61:05If you use the technical language from a 2017 NIH

61:10document, and you read that language very narrowly,

61:14I think you can make a credible argument that he did not.

61:19There's a question, though, and Francis Collins

61:22talked about that in his interview with you.

61:25But then there's a question that we know from now

61:28that we have the information of the reports submitted

61:31by EcoHealth Alliance to the NIH, and some of which

61:36were late or not even delivered, that some of this research

61:40was done on MERS, Middle Eastern Respiratory Syndrome virus.

61:45And if that was the case, there is, I think,

61:49a colorable argument that that would be considered

61:53gain of function research even by the narrow language

61:58of that 2017 document.

61:59But I definitely think, and I've said this repeatedly,

62:02that Rand Paul can be right, and Tony Fauci can be right.

62:08And the question is, how are we defining gain of function?

62:12And that's why I've always said the question in my mind

62:14isn't, was it or wasn't it gain of function,

62:17as if that's like a binary thing, if not, grade,

62:22and if yes, guilty.

62:23The question is just, what work was being done at the Wuhan

62:27Institute of Virology?

62:28What role, if any, did US government funding

62:33play in supporting that work?

62:36And what rights do we all have as human beings

62:41and as American citizens and taxpayers

62:43to get all of the relevant information about that?

62:47So let's try to kind of dissect this.

62:51So who frustrates you more, Rand Paul or Anthony

62:55Fauci in his discussion or the discussion itself?

62:57So for example, gain of function is

63:00a term that's kind of more used just

63:06to mean playing with viruses in the lab

63:11to try to develop more dangerous viruses.

63:16Is this kind of research a good idea?

63:22Is it also a good idea for us to talk about it in public,

63:26in the political way that it's been talked about?

63:29Is it OK that US may have funded gain of function research

63:38elsewhere?

63:39I mean, it's kind of assumed, just like with Bill Clinton,

63:43there was very little discussion of, I think,

63:46correct me if I'm wrong, but whether it's

63:49OK for a president, male or female,

63:54to have extramarital sex or is it

63:58OK for a president to have extramarital sex

64:04with people on his staff or her staff?

64:08It was more the discussion of lying, I think.

64:12It was, did you lie about having sex or not?

64:16And in this gain of function discussion,

64:18what frustrates me personally is there's not

64:21a deep philosophical discussion about whether we

64:23should be doing this kind of research

64:25and what are the ethical lines, research on animals at all.

64:32Those are fascinating questions.

64:33Instead, it's a gotcha thing.

64:36Did you or did you not fund research on gain of function?

64:40And did you fund, it's almost like a bioweapon.

64:43Did you give money to China to develop this bioweapon that

64:47now attacked the rest of the world?

64:49So I mean, all those things are pretty frustrating,

64:52but is there, I think, the thing you

64:56can untangle about Anthony Fauci and gain of function

64:59research in the United States and the EcoHealth Alliance

65:01and Wuhan Institute of Virology that's clarifying.

65:07What were the mistakes made?

65:08Sure.

65:09So on gain of function, there actually

65:11has been a lot of debate.

65:14I mentioned before in 2011, these first papers,

65:18there was a big debate.

65:20Mark Lipsitch, who's formerly at Harvard now

65:22with the US government working in the president's office,

65:26he led a thing called the Cambridge Group that

65:29was highly critical of this work,

65:32basically saying we're creating monsters.

65:35They had the funding pause in 2014.

65:39They spent three years putting together a framework,

65:42and then they lifted it in 2017.

65:45So we had a thoughtful conversation.

65:47Unfortunately, it didn't work.

65:48And I think that's where we are now.

65:50So I absolutely think that there are real issues

65:54with the relationship between the United States government

65:58and EcoHealth Alliance, and through that,

66:01the EcoHealth Alliance with the Wuhan Institute of Virology.

66:05And one issue is just essential transparency,

66:08because as I see it, it's most likely the case

66:10that we transferred a lot of our knowledge and plans and things

66:14to the Wuhan Institute of Virology.

66:16And again, I'm sure that Xiaojiang Li is not herself

66:22a monster.

66:23I'm sure of that, even though I've never met her.

66:26But there are just a different set of pressures

66:29on people working in an authoritarian system

66:31than people who are working in other systems.

66:33That doesn't mean it's entirely different.

66:36And so I absolutely think that we shouldn't give $1

66:40to an organization, and certainly a virology institute,

66:44where you don't have full access to their records,

66:47to their databases.

66:49We don't know what work is happening there.

66:52And I think that we need to have that kind of full examination.

66:57So I understand what Dr. Fauci is doing is saying,

67:01hey, what I hear Dr. Fauci saying,

67:03what I hear from you, Rand Paul, is

67:05you're accusing me of starting this pandemic.

67:08And you're using gain of function as a proxy for that.

67:11And we have, when there are Senate hearings,

67:13every senator gets five minutes.

67:15And the name of the game is to translate your five minutes

67:18into a clip that's going to run on the news.

67:22And so I get that there is that kind of gotcha.

67:25But I also think that Dr. Fauci and the National

67:31Institute of Allergy and Infectious Diseases and the NIH

67:35should have been more transparent.

67:37Because I think that in this day and age, where

67:41there are a lot of people poking around

67:42and this whole story of COVID origins,

67:45we would not be where we are if it

67:47wasn't for a relatively small number of people.

67:51And I'm part of, there are two, as I know, two groups.

67:54One is these internet sleuths known as Drastic.

67:57And a number of them are part of a group

68:00that I'm part of called, it's not our official name,

68:03but called the Paris Group.

68:04It's about two dozen experts around the world,

68:08but centered around some very high level French academics.

68:13So we've all been digging and meeting with each other

68:16regularly since last year.

68:19And our governments across the board, certainly China,

68:22but including the United States, haven't

68:23been as transparent as they need to be.

68:27So definitely mistakes were made on all sides.

68:31And that's why for me from day one,

§08Transcript · 1:08:33–1:18:35

68:33I've been calling for a comprehensive investigation

68:37into this issue that certainly obviously looks at China,

68:40but we have to look at ourselves.

68:41We did not get this right.

68:43So do you, I'm just gonna put Rand Paul aside here.

68:50Politician playing political games, it's very frustrating,

68:53but it is what it is on all sides.

68:56Anthony Fauci, you think should have been more transparent

68:59and maybe more eloquent in expressing the complexity

69:10of all of this, the uncertainty in all of this.

69:12Yeah, and I get that it's really hard to do that

69:16because let's say you have one, you speak a paragraph

69:21and it's got four sentences.

69:23And one of those sentences is the thing

69:25that's going to be turned into Twitter.

69:27All right, let me put it back.

69:28I get really, so I'll try not to be emotional about this,

69:32but I've heard Anthony Fauci a couple of times now

69:39say that he represents science.

69:43I know what he means by that.

69:45He means in this political bickering,

69:48all that kind of stuff that for a lot of people,

69:52he represents science, but words matter.

69:56And this isn't just clips.

69:58I mean, maybe I'm distinctly aware of that

70:00doing this podcast.

70:01Yeah, I talked for hundreds of hours now,

70:05maybe over a thousand hours,

70:07but I'm still careful with the words.

70:11I'm trying not to be an asshole

70:13and I'm aware when I'm an asshole

70:14and I'll apologize for it.

70:17If the words I represent science left my mouth,

70:21which they very well could,

70:23I would sure as hell be apologizing for it

70:26and not because I got in trouble,

70:29I would just feel bad about saying something like that.

70:31And even that little phrase, I represent science.

70:36No, Dr. Fauci, you do not represent science.

70:39I love science, the millions of scientists

70:42that inspired me to get into it.

70:45To fall in love with the scientific method

70:48in the exploration of ideas through the rigor of science,

70:53that Anthony Fauci does not represent.

70:55He's one, I believe, great scientist of millions.

70:59He does not represent anybody.

71:02He's just one scientist.

71:04And I think the greatness of a scientist

71:07is best exemplified in humility

71:10because the scientific method basically says,

71:13you're standing before the fog, the mystery of it all,

71:19and slowly chipping away at the mystery.

71:22And it's embarrassing, it's humiliating

71:27how little you know, that's the experience.

71:29So the great scientists have to have humility to me.

71:33And especially in their communication,

71:34they have to have humility.

71:36And I mean, I don't know,

71:37and some of it is also words matter

71:39because great leaders have to have the poetry of action.

71:45They have to be bold and inspire action

71:49across millions of people.

71:52But you also have to, through that poetry of words,

71:58express the complexity of the uncertainty

72:02you're operating under.

72:04Be humble in the face of not being able

72:06to predict the future or understand the past,

72:09or really know what's the right thing to do,

72:11but we have to do something.

72:13And through that, you have to be a great leader

72:16that inspires action.

72:17And some of that is just words.

72:20And he chose words poorly.

72:22I mean, so I'm all torn about this.

72:25And then there's politicians, they're taking those words

72:28and magnifying them and playing games with them.

72:31And of course, that's a disincentive

72:34for the people who do, the scientific leaders

72:37that step into the limelight to say any more words.

72:41So they kind of become more conservative

72:43with the words they use.

72:45I mean, it just becomes a giant mess.

72:47But I think the solution is to ignore all of that

72:52and to be transparent, to be honest, to be vulnerable.

72:56And to express the full uncertainty

73:01of what you're operating under,

73:03to present all the possible actions

73:05and to be honest about the mistakes they made in the past.

73:08I mean, there's something, even if you're not

73:10directly responsible for those mistakes,

73:13taking responsibility for them is a way to win people over.

73:18I don't think leaders realize this often

73:20in the modern age, in the internet age.

73:23They can see through your bullshit.

73:24And it's really inspiring when you take ownership.

73:29So to do the thought experiment in public,

73:32do a thought experiment if there was a lab leak

73:35and then lay out all the funding, the EcoHealth Alliance,

73:38all the incredible science going on at the Wuhan Institute

73:43of Virology and the NIH.

73:46Lay out all the possible ethical problems.

73:48Lay out all the possible mistakes that could have been made

73:53and say like, this could have happened.

73:56And if this happened, here's the best way to respond to it

73:59and to prevent it in the future.

74:00And just lay all that complexity out.

74:02I wish we would have seen that.

74:06And I have hope that this conversation,

74:09conversations like it, your work,

74:11and books on this topic will inspire young people today

74:15when they become in the Anthony Fauci's role

74:19to be much more transparent and much more humble

74:22and all those kinds of things.

74:23That this is just a relic of the past

74:26when there's a person, no offense to me,

74:28in a suit that has to stand up and speak

74:31with clarity and certainty.

74:33I mean, that's just a relic of the past.

74:34Is my hope.

74:39But...

74:40Do you mind if I...

74:41Yeah, please.

74:41I agree with a great deal of what you said.

74:46And it's really unfortunate that our,

74:49certainly the Chinese government, as I said before,

74:51our government wasn't as transparent

74:55as I feel they should have been,

74:56particularly in the early days of the pandemic

74:59and particularly with regard to the issue

75:02of pandemic origins.

75:03I mean, we know that Dr. Fauci was on calls

75:06with people like Christian Anderson and Scripps and others

75:10in those early days, raising questions.

75:13Is this an engineered virus?

75:15There were a lot of questions.

75:17And it's kind of sad.

75:19I mean, as I mentioned before, I've been one,

75:23I mean, and certainly there were others,

75:25but there weren't a lot of us,

75:27of the people who from the earliest days of the pandemic

75:30were raising questions about, hey, not so fast here.

75:34And I launched my website on pandemic origins

75:38in April of last year, April, 2020.

75:41It got a huge amount of attention.

75:42And actually my friend, Matt Pottinger,

75:44who is the deputy national security advisor,

75:46when he was reaching out to people in the US government

75:50and in allied government saying,

75:51hey, we should look into this,

75:54what he was sending them was my website.

75:56It wasn't some US government information.

76:00And by the way, people should still go to the website.

76:02You keep updating it and it's an incredible resource.

76:07Thank you, thank you, jamiemetzel.com.

76:10And it's really unfortunate that our governments

76:13and international institutions for pretty much all of 2020

76:18weren't doing their jobs of really probing this issue.

76:22People were hiding behind this kind of false consensus.

76:26And I'm critical of many people,

76:28even when I heard Francis Collins interview with you,

76:32I just felt, well, he wasn't as balanced

76:35on the issue of COVID origins.

76:37Certainly Dr. Fauci could have in his conversation

76:41with Rand Paul, it wasn't even a conversation,

76:43but in some process in the aftermath,

76:46could have laid things out a bit better.

76:48He did say, and Francis Collins did say

76:50that we don't know the origins and that was a shift

76:54and we need to have an investigation.

76:56So now, but having said all of that,

77:00I do kind of one, I have tremendous respect for Dr. Fauci

77:04for the work that he's done on HIV AIDS.

77:06I mean, I have been vaccinated with the Moderna vaccine.

77:10Dr. Fauci was a big part of the story

77:14of getting us these vaccines

77:15that have saved millions and millions of lives.

77:19And so I don't think, I mean, there's a lot to this story.

77:23And then the second thing is it's really hard

77:26to be a public health expert

77:28because you have your mission is public health.

77:32And so, and you have to, if you are leading

77:35with all of your uncertainty,

77:37it's a really hard way to do things.

77:40And so like, even now, like if I go to CVS

77:43and I get a Tylenol, somebody has done a calculation

77:47of how many people will die from taking Tylenol

77:51and they say, well, all right, we can live with that.

77:54And that's why we have regulation.

77:55And so all of us are doing kind of summaries.

77:59And then we have people in public health who are saying,

78:00wow, we've summed it all up and you should do X.

78:04You should get your kids vaccinated for measles.

78:09You should not drive your car at a hundred miles an hour.

78:12You should, don't drink lighter fluid,

78:15whatever these things are.

78:17And we want them to kind of give us broad guidelines.

78:20And yet now our information world is so fragmented

78:25that if you're not being honest about something,

78:29something material, someone's going to find out

78:33and it's going to undermine your credibility.

§09Transcript · 1:18:35–1:29:40

78:35And so I agree with you that there's a greater requirement

78:41for transparency now.

78:43Maybe there always has been,

78:44but there's an even greater requirement for it now

78:48because people want to trust that you're speaking honestly

78:53and that you're saying, well, here's what I know.

78:56And this is based on what I know,

78:58here are the conclusions that I draw.

79:00But if it's just, and again, I don't think the words,

79:03I'm science or whatever it was are the right words.

79:06But if it's just, trust me because of who I am,

79:10I don't think that flies anywhere anymore.

79:14Can I just ask you about the Francis Collins interview

79:18that I did, if you got a chance to hear that part.

79:20I think in the beginning we talk about the lab leak.

79:23What are your thoughts about his response,

79:25basically saying it's worthy of an investigation,

79:28but I mean, I don't know how you would interpret it.

79:33I see, it's funny because I heard it in the moment

79:39as it's great for the head of NIH

79:44to be open minded on this.

79:46But then the internet and Mr. Joe Rogan

79:51and a bunch of friends and colleagues told me that,

79:55yeah, well, that's too late and too little.

79:58Yeah, so first let me say, I've been on Joe's podcast twice

80:03and I love the guy, which doesn't mean that I agree

80:06with everything he does or says.

80:10And on this issue, and I'm normally a pretty calm

80:13and measured guy, and when you're just out running

80:17with your AirPods on and you start yelling

80:21into the wind in Central Park,

80:23nobody else knows why you're yelling, but well.

80:27So that you had such a moment?

80:28I had a moment with Collins.

80:30And again, Francis Collins is someone I respect enormously.

80:34I mean, I live a big chunk of my life living in the world

80:38of genetics and biotech and my book, Hacking Darwin

80:42is about the future of human genetic engineering

80:45and his work on the Human Genome Project

80:47and so many other things have been fantastic.

80:49And I'm a huge fan of the work of NIH.

80:53And he was right to say that the Chinese government

80:56hasn't been forthcoming and we need to look into it.

80:58But then you asked him, well, how will we know?

81:01And then his answer was,

81:03we need to find the intermediate host.

81:06Remember I said before, and so that made it clear

81:09that he thought, well, we should have an investigation,

81:13but it comes from nature and we just need to find

81:16that whatever it is, that intermediate animal host

81:20in the wild, and that'll tell us the story.

81:22So he already had the conclusion in mind

81:25and they're just waiting for the evidence

81:27to support the conclusion.

81:28That was my feeling.

81:29I felt like he was open in general, but he was tilting.

81:33And again, your first question was where do I fall?

81:36He was like, I'm 85% or whatever it is, 80, 75, 90,

81:42whatever it is in the direction of a lab incident.

81:45It made it feel that he was 90, 10 in the other direction,

81:49which is still means that he's open minded

81:52about the possibility.

81:54And that's why, in my view, every single person

81:58who talks about this issue,

81:59I think the right answer in my view is,

82:02we don't know conclusively.

82:04In my, then this is my personal view,

82:06the circumstantial evidence is strongly in favor

82:08of a lab incident origin,

82:10but that could immediately shift

82:11with additional information.

82:13We need transparency, but we should come together

82:18in absolutely condemning the outrageous coverup

82:23carried out by the Chinese government,

82:25which to this day is preventing any meaningful investigation

82:30into pandemic origins.

82:31We have, if you use the economist numbers,

82:3515 million people who are dead as a result of this pandemic.

82:39And I believe that the actions of the Chinese government

82:44are disgracing the memory of these 15 million dead.

82:50They're insulting the families and the billions of people

82:54around the world who have suffered

82:56from this totally avoidable pandemic.

83:00And whatever the origin, the fact the criminal coverup

83:03carried out by the Chinese government,

83:06which continues to this day, but most intensely

83:09in the first months following the outbreak,

83:11that's the reason why we have so many dead.

83:16And certainly, as I was saying before,

83:18I and a small number of others have been carrying this flame

83:22since early last year, but it's kind of crazy

83:26that our governments haven't been demanding it.

83:29And we can talk about the World Health Organization process,

83:33which was deeply compromised in the beginning.

83:35Now it's become much, much better.

83:38But again, it was the pressure of outsiders

83:42that played such an important role in shifting

83:44our national and international institutions.

83:48And while that's better than nothing,

83:50it would have been far better if our governments

83:53and international organizations

83:55had done the right thing from the start.

83:56If I could just make a couple of comments about Joe Rogan.

84:04So there's a bunch of people in my life

84:08who have inspired me, who have taught me a lot,

84:11who I even look up to, many of them are alive,

84:17most of them are dead.

84:19I wanna say that Joe said a few critical words

84:22about the conversation with Francis Collins,

84:24most of it offline, with a lot of great conversations

84:28about it, some he said publicly.

84:32And he was also critical to say that me asking hard questions

84:45in an interview is not my strong suit.

84:48And I really want to kind of respond to that,

84:53which I did privately as well, but publicly,

84:56to say that Joe is 100% right on that.

85:01But that doesn't mean that always has to be the case.

85:04And that is definitely something I wanna work on.

85:06Because most of the conversations I have,

85:08I wanna see the beautiful ideas in people's minds.

85:13But there's some times where you have to ask

85:15the hard questions to bring out the beautiful ideas.

85:20And it's hard to do.

85:23It's a skill.

85:24And Joe is very good at this.

85:26He says the way he put it in his criticisms,

85:29and he does this in his conversations,

85:31which is, whoa, whoa, whoa, stop, stop, stop, stop, stop.

85:34There's a kind of sense like,

85:36did you just say what you said?

85:38Let's make sure we get to the bottom,

85:42we'll clarify what you mean.

85:44Because sometimes really big negative or difficult ideas

85:54can be said as a quick aside in a sentence,

85:59like it's nothing, but it could be everything.

86:02And you wanna make sure you catch that

86:04and you talk about it.

86:06And not as a gotcha, not as a kinda way

86:10to destroy another human being,

86:12but to reveal something profound.

86:14And that's definitely something I wanna work on.

86:16I also want to say that, as you said,

86:22you disagree with Joe on quite a lot of things.

86:24So for a long time, Joe was somebody

86:26that I was just a fan of and listened to.

86:28He's now a good friend.

86:30And I would say we disagree more than we agree.

86:34And I love doing that.

86:38But at the same time, I learned from that.

86:41So it's like dual, like nobody in this world

86:46can tell me what to think.

86:48But I think everybody has a lesson to teach me.

86:54I think that's a good way to approach it.

86:57Whenever somebody has words of criticism,

87:00I assume they're right and walk around with that idea

87:05to really sort of empathize with that idea

87:07because there's a lesson there.

87:09And oftentimes, my understanding of a topic

87:18is altered completely or it becomes much more nuanced

87:22or much richer for that kind of empathetic process.

87:27But definitely, I do not allow anybody

87:31to tell me what to think, whether it's Joe Rogan

87:35or Fyodor Dostoevsky or Nietzsche or my parents

87:39or the proverbial girlfriend, which I don't actually have.

87:47But she's still busting my balls.

87:49Exactly, exactly.

87:51In my imagination, I have a girlfriend in Canada

87:55that I have imagined, exactly, imagining conversations.

88:00So I want to mention that.

88:01But also, I don't know if you've gotten a chance

88:04to see this, but I'd love to also mention

88:06this Twitter feud between two other interesting people,

88:12which is Brett Weinstein and Sam Harris

88:15or Sam Harris and others in general.

88:18And it kind of breaks my heart that these two people

88:22I listen to that are very thoughtful about a bunch of issues.

88:25Let's put COVID aside because people are very emotional

88:29about this topic.

88:30I mean, I think they're deeply thoughtful and intelligent,

88:37whether you agree with them or not.

88:39And I always learn something from their conversations.

88:42And they are legitimately or have been

88:44for a long time friends.

88:46And it's a little bit heartbreaking to me

88:49to see that they basically don't talk in private anymore.

88:53And there's occasional jabs on Twitter.

88:57And I hope that changes.

89:00I hope that changes in general for COVID,

89:02that COVID brought out the, I would say,

89:06the most emotional sides of people, the worst in people.

89:10And I think there hasn't been enough love

89:14and empathy and compassion.

89:16And to see two people from whom I've learned a lot,

89:20whether it's Eric Weinstein, Brett Weinstein, Sam Harris,

89:23you can criticize them as much as you want,

89:25their ideas as much as you want.

89:27But if you're not sufficiently open minded

89:31to admit that you have a lot to learn

89:33from their conversations, I think you're not being honest.

89:37And so I do hope they have those conversations.

§10Transcript · 1:29:40–1:39:15

89:40And I hope we can kind of,

89:42I think there's a lot of repairing to be done post COVID

89:45of relationships, of conversations.

89:49And I think empathy and love can help a lot there.

89:53This is also just a, I talked to Sam privately,

89:58but this is also a public call out

90:01to put a little bit more love in the world.

90:08And for these difficult conversations to happen.

90:14Because Brett Weinstein could be very wrong

90:19about a bunch of topics here around COVID,

90:25but he could also be right.

90:27And the only way to find out

90:29is to have those conversations.

90:31Because there's a lot of people listening

90:32to both Sam Harris and Brett Weinstein.

90:35And if you go into these silos

90:39where you just keep telling each other

90:44that you are the possessors of truth

90:46and nobody else is the possessor of truth,

90:48what starts happening is you both lose track

90:53or the capability of arriving at the truth.

90:56Because nobody's in the possession of the truth.

90:58So anyway, this is just a call out

90:59that we should have a little bit more conversation,

91:01a little bit more love.

91:02I totally agree.

91:04And both of those guys are guys who I respect.

91:08And as you know, Brett, and again, as I mentioned,

91:11they're just a handful of us,

91:13who were the early people raising questions

91:16about the origins of this.

91:17Of this pandemic, right.

91:19He was there also talking.

91:21So people have heard him speak quite a bit

91:24about any viral drugs and all that kind of stuff.

91:26But he was also raising concerns about lab leak early on.

91:30Yeah, exactly.

91:31And so, but I completely agree with you

91:33that we don't have to agree with everybody,

91:37but it's great to have healthy conversations.

91:40That's how we grow.

91:42And absolutely, we live in a world where we're kind of,

91:46if we're not careful,

91:47pushed into these little information pockets.

91:49And certainly on social media,

91:51I have different parts of my life.

91:53One is focusing on issues of COVID origins.

91:58And then I have genetics and biotechnology.

92:00And then I have, which maybe we'll talk about later,

92:02one shared world, which is about

92:04how do we build a safer future?

92:06And when I say critical things like the Chinese government,

92:10we'd have to demand a full investigation

92:12into pandemic origins.

92:14This is an outreach.

92:15Then it's really popular.

92:16When I say, let's build a better future

92:19for everyone in peace and love,

92:20it's like, wow, three people liked it.

92:22And one was my mother.

92:24And so I just feel like we need to build,

92:27we used to have that connectivity just built in

92:32because we had these town squares

92:33and you couldn't get away from them.

92:35Now we can get away from them.

92:37So engaging with people who are of a different background

92:41is really essential.

92:42I'm on Fox News sometimes three, four times a week.

92:47And I wouldn't, in my normal life,

92:49I'm not watching that much of Fox News

92:53or even television more generally.

92:56But I just feel like if I just speak to people

92:58who are very similar to me, maybe it'll be comfortable.

93:03But what have I contributed?

93:05So I think we really have to have

93:07those kinds of conversations and recognize

93:11that at the end of the day, most people want to be happy.

93:15They want to live in a better world.

93:17They maybe have different paths to get there.

93:20But if we just break into camps

93:22that don't even connect with each other,

93:24that's a much more dangerous world.

93:28Let's dive back into the difficult pool.

93:32Just like you said, in the English speaking world,

93:36it seems popular, almost easy to demonize China.

93:43The Chinese government, I should say.

93:46But even China, like there's this kind of gray area

93:50that people just fall into.

93:52And I'm really uncomfortable with that.

93:54Perhaps because in my mind, in my heart, in my blood

93:58are echoes of the Cold War and that kind of tension.

94:01But it feels like we almost desire conflict.

94:09So we see demons when there is none.

94:12So I'm a little cautious to demonize.

94:15But at the same time, you have to be honest.

94:18So it's like honest with the demons that are there

94:22and honest when they're not.

94:25This is kind of a geopolitical therapy session of sorts.

94:29So let's keep talking about China

94:31a little bit from different angles.

94:33So let's return to the director of the Center

94:37of Emerging Infectious Disease

94:39at the Wuhan Institute of Virology, Xi Zhengli,

94:44colloquially referred to as Batwoman.

94:47So do you think she's lying?

94:51Yes.

94:52Do you think she's being forced to lie?

94:54Yes.

94:55I've known a bunch of virologists

94:58in private and public conversation

95:00that respect her as a human being, as a scientist.

95:03I respect her as a human being.

95:05Sorry, as a scientist, not a human being.

95:07Because I think they don't know the human.

95:08They know the scientists.

95:09And they respect her a lot as a scientist.

95:11Yeah, I respect her.

95:12I've never met her.

95:13We had one exchange, which I'll mention in a second

95:16in a virtual forum.

95:17But I do respect her.

95:18I actually think that she is somebody

95:20who has tried to do the right thing.

95:23She was one of the heroes of tracking down

95:25the origins of SARS 1.

95:27And that was a major contribution.

95:31But as we talked about earlier,

95:34it's a different thing living, being a scientist,

95:38or really kind of anything.

95:40It's different being one of those people

95:43in an authoritarian society

95:47than it is being in a different type of society.

95:50And so when Xi Zhengli said that the reason

95:54the WIV database was taken offline in September 19

96:00was because of computer hacks,

96:02I don't think that's the story.

96:03I don't think she thinks that's the story.

96:07When I asked her in March of 2021, March of this year,

96:12in a Rutgers online forum,

96:15when I asked her whether the Chinese military

96:18had any engagement with the Wuhan Institute of Virology

96:22in any way, and she said, absolutely not, paraphrasing,

96:26I think she was lying.

96:27Do I think that she had the ability to say,

96:30well, either one, yes, but I can't talk about it,

96:34or I know there are a lot of things

96:36that are happening at this institute

96:38that I don't know about, and that could be one.

96:42Could she have said that the personnel

96:46at the Wuhan Institute of Virology

96:48have all had to go through classification training

96:52so that they can know about what can and can't be said?

96:57Like she could have said all those things,

96:59but she couldn't say all of those things.

97:01And I think that's why so many, at least in my view,

97:07so many people certainly in the Western world

97:11got this story wrong from the beginning,

97:13because if your only prism was the science,

97:17and you just assumed this is a science question

97:20to be left to the scientists,

97:22should Zhengli is just like any scientist

97:26working in Switzerland or Norway,

97:29the Chinese government isn't interfering in any way,

97:33and we can trust them, that would lead you down one path.

97:37In my view, the reason why I progressed as I did

97:40is I felt like I had two keys,

97:42and I had one key as I live in the science world

97:45through my work with WHO and my books and things like that.

97:50But I also have another part of my life

97:52in the world of geopolitics as an Asia quote unquote expert

97:57and former National Security Council official

98:00and other things.

98:01And I felt for me, I needed both keys to open that door.

98:06But if I only had the science key,

98:08I wouldn't have had the level of doubt and suspicion

98:11that I have.

98:12But if my starting point was only doubt and suspicion,

98:16well, it's coming from China,

98:17it must be that the government is guilty,

98:20like that wouldn't help either.

98:24I wonder what's in her mind,

98:26whether it's fear or habit,

98:30because I think a lot of people in the former Soviet Union,

98:35it's like Chernobyl, it's not really fear,

98:38it's almost like a momentum.

98:40It's like the reason I showed up to this interview

98:45wearing clothes, as opposed to being naked.

98:48It's like, all right.

98:51It's like, it's just all of us are doing the clothes thing.

98:55Although there was a startup years ago called Naked News.

98:59Did you ever hear about that?

99:00They just would read the exact news.

99:02With naked.

99:03No, after each story, they'd take something off

99:06until the end, I don't think.

99:08It's a good idea for a podcast.

99:09They have an IPO.

99:10Stay tuned, next time I'm with Michael Miles.

99:13Yeah.

99:14Okay.

§11Transcript · 1:39:16–1:49:19

99:16So what do you think,

99:18I mean, because the reason I asked that question is,

99:22how do we kind of take steps to improve

99:25without any kind of revolutionary action?

99:27You could say, we need to inspire the Chinese people

99:32to elect, to sort of revolutionize the system

99:37from within, but like, who are we to suggest that?

99:42Because we have our flaws too.

99:44We should be working on our flaws as well.

99:47And so, but at the individual scientist level,

99:51what are the small acts of rebellion that could be done?

99:55How can we improve this?

99:57Well, so I don't know about small acts of rebellion,

100:01but I'll try to answer your question

100:03from a few different perspectives.

100:07So right now, actually, as we speak,

100:10there is a special session

100:12of the World Health Assembly going on.

100:14And the World Health Assembly is the governing authority

100:17over the World Health Organization,

100:19where it's represented by states and territories,

100:22194 of them, tragically not including Taiwan,

100:26because of the Chinese government's assistance.

100:29But they're now beginning a process

100:31of trying to negotiate a global pandemic treaty

100:35to try to have a better process

100:37for responding to crises exactly like we're in.

100:42But unfortunately, for the exact same reasons

100:45that we have failed, I mean, we had a similar process

100:48after the first SARS, we set up what we thought

100:50was the best available system,

100:52and it has totally failed here.

100:55And it's failed here because of the inherent pathologies

101:00of the Chinese government system.

101:02We are suffering from a pandemic that exists

101:06because of the internal pathologies of the Chinese state.

101:11And that's why on one hand, I totally get this impulse.

101:14Well, we do it our way, they do it their way.

101:17Who's to say that one way is better?

101:20And certainly right now in the United States,

101:23we're at each other's throats.

101:25We have a hard time getting anything meaningful done.

101:28And I'm sure there are people who are saying,

101:31well, that model looks appealing.

101:33But just as people could look to the United States

101:37and say, well, because the United States

101:39has such a massive reach, what we do domestically

101:41has huge implications for the rest of the world,

101:44they become stakeholders in our politics.

101:48And that's why I think for a lot of years,

101:49people have just been looking at US politics,

101:52not because it's interesting,

101:53but because the decisions that we make

101:55have big implications for their lives.

101:58The same is true for ours.

101:59You could say that the lack of civil and political rights

102:04in China is, I mean, it's up to the Chinese,

102:08not even people, because they have no say,

102:10but to their government.

102:12And they weren't democratically elected,

102:14that they are recognized as the government.

102:17But some significant percentage of the 15 million people

102:23now dead from COVID are dead

102:26because in the earliest days following the outbreak,

102:29whatever the origin, the voices of people

102:33sounding the alarm were suppressed,

102:35that the Chinese government had an,

102:37just like in Chernobyl, the Chinese government

102:39had a greater incentive to lie

102:42to the international community than to tell the truth.

102:46And everybody was incentivized

102:49to pretty much do the wrong thing.

102:51And so that's why I think one of the big messages

102:55of this pandemic is that all of our fates

102:57are tied to everybody else's fates.

103:00And so while we can say and should say,

103:02well, let's focus on our own communities and our countries,

103:06we're all stakeholders in what happens elsewhere.

103:09Can I ask you a weird question?

103:14So I'm gonna do a few podcast interviews

103:20with interesting people in Russia, in the Russian language,

103:24because I could speak Russian.

103:27And a lot of those people have,

103:30are not usually speaking in these kinds of formats.

103:36Do you think it's possible to interview Xi Jinping?

103:40Do you think it's possible to interview somebody like her

103:44or anyone in the Chinese government?

103:47I think not.

103:49And I think the reason is

103:52because I think they would, one,

103:54be uncomfortable being in any environment

103:57where really unknown questions will be asked.

104:02And I actually, so as you know, on this topic,

104:06the Chinese, as I mentioned earlier,

104:07the Chinese government has a gag order on Chinese scientists.

104:10They can't speak without prior government approval.

104:13Xu Zhengli has been able to speak.

104:15And she's spoken at a number of forums.

104:17I mentioned this Rutgers event.

104:19What was the nature of that forum, the Rutgers event?

104:23All of them were kind of science conversations

104:26about the pandemic, including the origins issue.

104:33But I think that she, in her response to my question,

104:37it was kind of this funny thing.

104:38So they had this event organized by Rutgers.

104:42And I went on, there was an online event on Zoom,

104:45but I got on there and I just realized

104:47it was very poorly organized.

104:49Like normally the controls that you would have

104:51about who gets to chat to who, who gets to ask questions,

104:54none of them were set.

104:56And so I kind of couldn't believe it.

104:58I was just sitting at home in my neon green fleece

105:02and I just started sending chat messages to Xu Zhengli.

105:06So you could, anybody could send any.

105:08Anybody could, it was insane.

105:09But I thought, wow, this is incredible.

105:11And so then it was unclear who got to ask questions.

105:16And so I was like posting questions

105:18and then I was sending chats to the organizers

105:20of the event saying, I really have a question.

105:24And first they said, well, you can submit your questions

105:27and we'll have submitted questions.

105:29And then if we have time, we'll open up.

105:31So I just, I mean, I just thought, well, what the hell?

105:33I just sent messages to everybody.

105:34And then the event was already done.

105:37They were 15 minutes over time.

105:39And then they said, all right,

105:40we have time just for one question.

105:42And it's Jamie Metzl.

105:44And like, as I'm sitting there in my running clothes,

105:47like I wasn't, I was like multitasking and I heard my name.

105:50And so I went diving back and I asked this question

105:55about, did you know all of the work that was happening

106:00at the Wuhan Institute of Virology, not just your work?

106:06And can you confirm that US intelligence has said

106:10that the military played a role,

106:14was engaged with the Wuhan Institute of Virology?

106:16Do you deny that the Chinese military was involved

106:19in any way with the Wuhan Institute of Virology?

106:21And as I said before, she said, this is crazy.

106:24Absolutely not.

106:26It got, it actually got,

106:27that one question got covered in the media

106:29because it was like, I think an essential question.

106:32But I just think that since then, to my knowledge,

106:35she's not been in any public forums,

106:38but that's why most people would be shocked

106:41that to date there has been no comprehensive

106:43international investigation into pandemic origins.

106:46There is no whistleblower provision.

106:49So if you're, my guess is there are at least tens,

106:52maybe hundreds of people in China

106:55who have relevant information

106:56about the origins of the pandemic who are terrified

107:00and don't dare share it.

107:01And let's just say somebody wanted

107:04to get that information out, to send it somewhere.

107:08There's no official address.

107:10The WHO doesn't have that, nobody has that.

107:13And so I would love, I mean, you may as well ask.

107:16I don't think it's likely that there'll be a yes,

107:21but it could well be that there are defectors

107:23who will want to speak.

107:25So let me also push back on this idea.

107:29So one, I want to ask if the language barrier is a thing.

107:33Because I've talked to,

107:34so I understand Russian culture, I think,

107:38or not understand, this is the thing.

107:40I don't understand basically anything in this world.

107:45But I mean, I hear the music that is Russian culture

107:50and I enjoy it.

107:51I don't hear that music for Chinese culture.

107:55It's just not something I've experienced.

107:57So it's a beautiful, rich, complex culture.

108:00And from my sense, it seems distant to me.

108:05Like whenever I look, even like we mentioned offline Japan

108:10and so on, I probably don't even understand

108:13Japanese culture.

108:14I believe I kind of do because I did martial arts

108:16my whole life, but even that, it's just so distant.

108:20People who've lived in Japan, foreigners for like 20 years

108:23say the exact same thing, yeah.

108:25This makes me sad.

108:26It makes me sad because I will never be able

108:29to fully appreciate the literature, the conversations,

108:34the people, the little humor and the subtleties.

108:38And those are all essential to understand

108:39even this cold topics of science.

108:43Because all of that is important to understand.

108:46So that's a question for me if you think

108:48language barriers a thing.

108:49But the other thing I just want to kind of comment on

108:52is the criticism of journalism that somebody like

108:57Shi Zhengli or even Shi Zhengpeng, just anybody in China,

109:05very skeptical to have really conversations

109:08with anybody in the western media.

109:11Because it's like what are the odds that they will try

109:16to bring out the beautiful ideas in the person.

§12Transcript · 1:49:19–1:58:57

109:19And honestly, this is a harsh criticism.

109:23I apologize, but I kind of mean it, is the journalists

109:30that have some of these high profile conversations

109:34often don't do the work.

109:36They come off as not very intelligent.

109:39And I know they're intelligent people.

109:41They have not done the research.

109:43They have not come up and like read a bunch of books.

109:46They have not even read the Wikipedia article.

109:48Meaning put in the minimal effort to empathize,

109:52to try to understand the culture of the people,

109:54all the complexities, all the different ideas in the spaces.

109:58Do all the incredible, not all,

110:00but some of the incredible work that you've done initially.

110:04Like that, you have to do that work to earn the right

110:07to have a deep real conversation with some of these folks.

110:11And it's just disappointing to me

110:13that journalists often don't do that work.

110:15Yeah, so on that, just first I completely agree with you.

110:19I mean, there is just an incredible beauty

110:22in Chinese culture and I think all cultures,

110:25but certainly China has such a deep and rich history,

110:29amazing literature and art and just human beings.

110:34I mean, I'm a massive critic of the Chinese government.

110:38I'm very vociferous about the really genocide in Xinjiang,

110:42the absolute effort to destroy Tibetan culture,

110:46the destruction of democracy in Hong Kong,

110:51incredibly illegal efforts to seize

110:54basically the entire South China Sea.

110:56And I could go on and on and on.

110:59But Chinese culture is fantastic.

111:02And I mean, I can't speak to every technical field,

111:05but just in terms of having journalists,

111:09and I'll speak to American journalists,

111:10people like Peter Hessler who have really invested the time

111:14to live in China, to learn the language, learn the culture.

111:19Peter himself, who is maybe one of our best journalists

111:22covering China from a soul level,

111:26he was kicked out of China.

111:27So it's very, very difficult.

111:30His stuff.

111:31His stuff.

111:32Yeah, it's really, and so for me,

111:32you talked about my website on pandemic origins.

111:36So when I launched it, I had it,

111:38I'm not a Chinese speaker,

111:40but I had the entire site translated into Chinese

111:44and I have it up on my website just because I felt like,

111:48well, if somebody, I mean, the great firewall

111:51makes it very, very difficult for people in China

111:53to access that kind of information.

111:56But I figured if somebody gets there

111:58and they wanna have it in their own language.

112:02But it's hard because the Chinese government

112:04is represented by these quote unquote wolf warriors,

112:08which is, it's like these basic ruffians.

112:11And I personally was condemned by name

112:15by the spokesman of the Chinese foreign ministry

112:17from the podium in Beijing.

112:20And so it's really hard because I absolutely think

112:25the American people and the Chinese people,

112:27I mean, maybe all people, but we have so much in common.

112:31I mean, yes, China is an ancient civilization,

112:36but they kind of wiped out their own civilization

112:38in the great leap forward and cultural revolution.

112:41They burned their scrolls, they smashed their artworks.

112:44And so it's a very young society,

112:47kind of like America is a young society.

112:50So we have a lot in common.

112:53And if we just kind of got out of our own ways,

112:57we could have a beautiful relationship,

112:59but there's a lot of things that are happening.

113:01Certainly the United States feels responsible

113:04to defend the post war international order

113:07that past generations helped build.

113:09And I'm a certain believer in that

113:11and China is challenging that and the Chinese government

113:16and they've shared that with that view

113:18with the Chinese people feel

113:19that they haven't been adequately respected.

113:21And now they're building a massive nuclear arsenal

113:26and all these other things to try to position themselves

113:29in the world with an articulated goal

113:31of being the lead country in the world.

113:33And that puts them at odds with the United States.

113:34So there are a lot of real reasons

113:37that we need to be honest about for division.

113:39But if that's all we focus on,

113:42if we don't say that there's another side of the story

113:45that brings us together,

113:47we'll put ourselves on an inevitable glide path

113:51to a terrible outcome.

113:53What do you make of Xi Jinping?

113:57So two questions.

113:57So one in general and two more on lab leak

114:01and his meeting with our president Biden

114:05in discussion of lab leak.

114:07So I feel that Xi Jinping has a very narrow goal

114:15articulated of establishing China

114:17as the lead country in the world

114:20by the 100th anniversary of the founding

114:22of the modern Chinese state.

114:26And it's ruthless and it's strategic.

114:29There's a great book called The Long Game by Rush Doshi

114:33who's actually now working in the White House

114:36about this goal and our pretty clearly articulated goal

114:41to subvert the post war international order

114:45and in China's interest.

114:47And maybe every leader wants to organize the world

114:50around their interest.

114:51But I feel that his vision of what that entails

114:56is not one that I think is shareable

114:59for the rest of the world.

115:00I mean, the strength of the United States

115:01with all of our flaws is particularly

115:04in that post war period,

115:06we put forward a model that was desirable

115:10to a lot of people.

115:11Certainly it was desirable to people in Western Europe

115:13and then Eastern Europe and Japan and Korea.

115:17Doesn't mean it's perfect.

115:18The United States is deeply flawed.

115:21As articulated to date,

115:23I don't think most people and countries

115:26would like to live in a Sinocentric world.

115:30And so I certainly, as I mentioned before,

115:32I'm a huge critic of what Xi Jinping is doing,

115:34the incredible brutality in Xinjiang,

115:39in Tibet and elsewhere.

115:42Yeah, the censorship one gives me a lot of trouble

115:47on the science realm and just in journalism

115:51and just the world that prevents us

115:53from having conversations with each other.

115:56Do you know about the Winnie the Pooh thing?

115:58Yes, I mean, it's ridiculous.

116:01So to me, that's such a good illustration

116:03of censorship being petty.

116:08But censorship has to be petty

116:09because the goal of censorship,

116:12maybe you experienced in the Soviet Union,

116:14is to get into your head.

116:16Like if it's just censorship,

116:17like you say down with the state

116:20and like you can't say that,

116:22but you can say all the other things up to that point,

116:26eventually people will feel empowered

116:28to say down with the state.

116:29And so I think the goal

116:30of this kind of authoritarian censorship

116:33is to turn you into the censor.

116:36And so the...

116:38Like self censor.

116:39Yeah, because they almost have to have you think,

116:41well, if I'm gonna make any criticism,

116:44maybe they're gonna come and get me.

116:45So it's safer to not do it.

116:48I mean, I've traveled through North Korea

116:50pretty extensively and I've seen that in its ultimate form,

116:53but that's what they're trying to do in China too.

116:56Yeah, so for people who are not familiar,

117:00it's such a clear illustration

117:01of just the pettiness of censorship

117:03and leaders, the corrupting nature of power.

117:07But there's a meme of Xi Jinping

117:10with, I guess, Barack Obama.

117:13And the meme is that he looks like Winnie the Pooh

117:18in that picture.

117:20And that was the President Xi Jinping

117:25looks like Winnie the Pooh.

117:26And I guess that became, because that got censored,

117:30like mentions of Winnie the Pooh got censored

117:32all across China.

117:33Winnie the Pooh became the unknowing revolutionary hero

117:38that represents freedom of speech and so on.

117:41But it's just such a absurd...

117:44Because we spend so much time in this conversation

117:47talking about the censorship

117:49that's a little bit more understandable to me,

117:52which is like, we messed up.

117:55And it wasn't, maybe it's almost understandable errors

117:59that happen in the progress of science.

118:02I mean, you could always argue

118:05that there's a lot of mistakes along the way

118:09and the censorship along the way caused the big mistake.

118:11You can argue that same way for the Chernobyl.

118:14But those are sort of understandable and difficult topics.

118:18Like Winnie the Pooh.

118:19But in your message, it shows both sides of the story.

118:22I mean, one, how petty authoritarian censors have to be.

118:26And that's why the messaging from the Chinese government

118:29is so consistent.

118:30No matter who you are,

118:32you have to be careful what you say.

118:33And that's why it's the story of Peng Shui,

118:37the tennis player.

118:38She dared raise her voice in an individual way.

118:42Jack Ma, the richest man in China,

118:46had a minor criticism of the Chinese government.

118:50He had basically disappeared from the public eye.

118:54Fan Bingbing, who's like one of the leading

§13Transcript · 1:58:57–2:08:08

118:57Chinese movie stars,

118:59she was seen as not loyal enough and she just vanished.

119:03And so the message is no matter who you are,

119:06no matter what level,

119:08if you don't mind everything you say,

119:11you could lose everything.

119:12I'm pretty hopeful, optimistic about a lot of things.

119:15And so for me, if the Chinese government stays

119:19with its current structure,

119:21I think what I hope they start fixing

119:24is the freedom of speech.

119:26But they can't.

119:27I mean, the thing is if they open up freedom of speech

119:32really in a meaningful way,

119:34they can't maintain their current form of government.

119:38And it's connected, as I was saying before,

119:40to the origins of the pandemic.

119:42I mean, if my hypothesis was right,

119:45that was the big choice that the national government had.

119:48Do we really investigate the origins of the pandemic?

119:51Do we deliver a message that transparency is required,

119:55public transparency is required from local officials?

119:58If they do that, the entire system collapsed.

120:02Pretty much everybody in China has a relative

120:06who has died as a result of the actions

120:09of the Communist Party,

120:10particularly in the Great Leap Forward.

120:12It's nearly 50 million people died

120:15as a result of Mao's disastrous policies.

120:18And yet why is Mao's picture still on Tiananmen Square

120:21and it's on the money?

120:23Because maintaining that fiction

120:26is the foundation of the legitimacy of the Chinese state.

120:29If people were allowed, just say what you want.

120:32Do you really think Mao was such a great guy,

120:35even though your own relatives are dead as a result?

120:39Do you really buy even on this story

120:43that China did nothing wrong,

120:45even though in the earliest days of the pandemic,

120:48these two, at least Chinese scientists themselves,

120:51courageously issued a preprint paper

120:54that was later almost certainly forcibly retracted,

120:58saying, well, this looks like this comes

121:00from one of the Wuhan labs that we're studying.

121:03Like if you opened up that window,

121:06I think that the Chinese government

121:09would not be able to continue in its current form.

121:12And that's why they cracked down at Tiananmen Square.

121:14That's why with Feng Shui, the tennis player,

121:17if they had let her accuse somebody

121:21from the Communist Party of sexual assault,

121:24and they said, okay, now people,

121:26you can use social media

121:28and you can have your me too moment

121:30and let us know who in the Chinese Communist Party

121:34or your boss in a business has assaulted you.

121:37Just like in every society,

121:38I'm sure there's tons of women

121:40who've been sexually assaulted, manipulated, abused by men.

121:45And so I certainly hope

121:48that there can be that kind of opening.

121:51But if I were an authoritarian dictator,

121:54that's the thing I would be most afraid of.

121:56Yeah, dictator perhaps,

121:58but I think you can gradually increase the freedom of speech.

122:01So I think you can maintain control over the freedom

122:04of press first.

122:06So control the press more,

122:08but let the lower levels sort of open up YouTube, right?

122:13Open up like where individual citizens can make content.

122:17I mean, there's a lot of benefits to that.

122:19And then from an authoritarian perspective,

122:22you can just say that's misinformation,

122:25that's conspiracy theories, all those kinds of things.

122:28But at least I think if you open up that freedom of speech

122:32at the level of the individual citizen,

122:35that's good for entrepreneurship,

122:38for the development of ideas,

122:39of exchange of ideas, all that kind of stuff.

122:41I just think that increased the GDP of the country.

122:44So I think there's a lot of benefits.

122:46I feel like you can still play,

122:48we're playing some like dark thoughts here,

122:50but I feel like you could still play the game of thrones,

122:54still maintain power while giving freedom to the citizenry.

123:00Like I think just like with North Korea is a good example

123:04of where cracking down too much

123:07can completely destroy your country.

123:10Like there's some balance you can strike in your evil mind

123:14and still maintain authoritarian control over the country.

123:17Obviously, it's not obvious,

123:20but I'm a big supporter of freedom of speech.

123:24I mean, it seems to work really well.

123:26I don't know what the failure cases

123:28for freedom of speech are.

123:30Probably we're experiencing them with Twitter

123:32and like where the nature of truth

123:34is being completely kind of flipped upside down.

123:38But it seems like on the whole,

123:41ability to defeat lies with more,

123:47not through censorship, but through more conversations,

123:50more information is the right way to go.

123:53Can I tell you a little story, true stories

123:54about North Korea?

123:56So a number of years ago, I was invited

123:58to be part of a small six person delegation

124:01advising the government of North Korea

124:04on how to establish special economic zones

124:07because other countries have used these SEZs

124:10as a way of building their economies.

124:13And when I was invited, I thought,

124:15well, maybe there's an opening.

124:17And I certainly believe in that.

124:19So we flew to China across the border into North Korea.

124:24And then we were met by our partners

124:27from the North Korean Development Organization.

124:30And then we zigzagged the country for almost two weeks

124:33visiting all these sites for where they were intended

124:38to create these special economic zones.

124:39And in each site, they had their local officials

124:42and they had a map and they showed us where everything

124:45that was going to be built.

124:47And the other people who were like really technical experts

124:50on how to set up a special economic zone,

124:52they were asking questions, well, like,

124:53should you put the entrance over here

124:55or shouldn't you put it over there

124:56and what if there's flooding?

124:58And I kept asking just these basic questions,

125:00like, what do you think you're going to do here?

125:02Why do you think you can be competitive?

125:05Do you know anything about who you're competing against?

125:07Are you empowering your workers to innovate

125:10because everybody else is innovating?

125:12So at the end of the trip, they flew us to Pyongyang

125:14and they put us in this,

125:15it looked kind of like the United Nations.

125:17They probably had 500 people there

125:20and I gave a speech to them.

125:22I obviously was in English and it was translated

125:26and I figured, you know, I've come all this way,

125:29I'm just going to be honest.

125:30If they arrest me for being honest, that's on them.

125:34And I said, I'm here because I believe

125:38we can never give up hope,

125:39that we always have to try to connect.

125:41I'm also here because I think that North Korea

125:45connecting to the world economy is an important first step.

125:50But having visited all of your special economic zone sites

125:52and having met with all of your, or many of your officials,

125:56I don't think your plan has any chance of succeeding

125:59because you're trying to sell into a global market,

126:03but you need to have market information that,

126:07and I gave examples of GE and others

126:10that the innovation can't only happen at one place.

126:14And if you want innovation to happen

126:17from the people who are doing this,

126:19you have to empower them, they have to have access,

126:22they have to have voice.

126:23I mean, nobody, I mean, the people after,

126:28they kind of had to condemn me

126:30because what I was saying was challenging.

126:32So I certainly agree with you.

126:33And then just one side story of then that night,

126:37and it was just kind of bizarre

126:39because North Korea is, it's so desperately poor,

126:42but they were trying to impress us.

126:44And so we had these embarrassingly sumptuous banquets.

126:49And so for our final dinner that night,

126:51really it looked like something from Beauty and the Beast.

126:54I mean, it was like China and waiters and tuxedos,

126:59and they had this beautiful dinner.

127:02And then afterwards,

127:04because we'd now spent two weeks

127:05with our North Korean partners,

127:07they brought out this karaoke machine

127:08and our North Korean counterparts,

127:11they sang songs to us in Korean.

127:15And so I said, well, we want to reciprocate.

127:18Do you have any English songs on your karaoke machine?

127:21It's North Korea, obviously they didn't.

127:23But there was, I said, well, I have an idea.

127:25And so there was one of the women

127:27who'd been part of the North Korean delegation.

127:30She was able just to play the piano,

127:32just like you could hum a tune

127:34and she could play it on the piano.

127:36And so I said, all right, here's this tune,

127:39which I whispered in her ear.

127:41When I give you the signal,

127:42just play this tune over and over.

127:45And so I got these, I mean, there were the six of us

127:48and maybe 20 North Koreans,

127:49and we were all in a circle,

127:51so everybody hold hands and then put your right,

127:54just try to put your right foot in front of your left

127:57and then left foot in front of the right, going sideways.

128:00And I said, all right, hit it.

128:02And she played a North Korean version of Hava Nagila.

128:06And I think it was the first

§14Transcript · 2:08:08–2:17:24

128:08and only horror that they've ever done in North Korea.

128:11That's hilarious.

128:12I survived.

128:13Was this recorded or no?

128:14It was not.

128:15Oh, no.

128:15Yeah, if they had free YouTube,

128:18this would have been a big one.

128:19Yeah.

128:21Let's return to the beginning

128:23and just patient zero.

128:28It's kind of always incredible to think

128:30that there's one human at which it all started.

128:33Yeah.

128:36Who do you think was patient zero?

128:38Do you think it was somebody that worked

128:42at Wuhan Institute of Virology?

128:47Do you think there was a leak of some other kind

128:52that led to the infection?

128:55What do we know?

128:55Because there's this December 8th slash December 16th case

128:59of maybe you can describe what that is.

129:04And then there's like, what's his name?

129:09Michael Warobey has a nice timeline.

129:12I'm sure you have a timeline.

129:14But he has a nice timeline that puts the average

129:17at like November something, like 18th and November 16th

129:22as the average estimate for when the patient zero

129:27got infected, when the first human infection happened.

129:30Yeah, so just two points.

129:32One is it may be that there's infectee zero

129:36and patient zero.

129:37It could be that the first person infected was asymptomatic

129:41because we know there's a lot of people

129:42who are asymptomatic.

129:44And then there's the question of, well, who is patient zero?

129:47Meaning the first person to present themselves

129:51in some kind of health facility

129:53where that diagnosis could be made.

129:56So can we actually linger on that definition?

129:58Yeah.

129:59So is that to you a good definition of patient zero?

130:02Okay, there's a bunch of stuff here

130:04because this virus is weird.

130:06So one is who gets infected, one who is infectious

130:11or the first person infect others.

130:14Yeah.

130:15And who shows up to a hospital.

130:17Yeah, so I think that's why I'm calling the first person

130:19to show up to a hospital who's diagnosed with COVID 19.

130:22I'm calling that person patient zero.

130:24There's also, there's somewhere the first person

130:28to be infected.

130:29And that person maybe never showed up in a hospital

130:32because maybe they were asymptomatic and never get sick,

130:36so got sick.

130:37So let me start with what I'm calling infectee zero.

130:40Here are some options.

130:41I talked before about some person who was a villager

130:46and some remote village.

130:47It's almost impossible to imagine, but possible to imagine

130:51because strange things happen.

130:54And that person somehow gets to Wuhan.

130:57By the way, just to still make that argument,

131:00there's not an argument, it's a statement,

131:01but strange things happen all the time.

131:05No, I agree.

131:06It doesn't mean that logic doesn't apply

131:09and probabilities don't apply, but we all,

131:11I mean, in general principle, everyone, if we were honest,

131:16should be agnostic about everything.

131:19Like I think I'm Jamie, but is there a 0.01% chance

131:23or 0.001% chance that I'm not?

131:27But it could be.

131:28I mean, how would I know?

131:29But there's a large number of people arguing

131:30about the meaning of the word I

131:31and that I'm Jamie.

131:33So exactly.

131:33What is consciousness?

131:34Exactly, exactly.

131:35So we could spend another three hours going into that one.

131:39So one possibility is there's some remote villager.

131:42Another possibility is there's somehow bizarrely,

131:47there are these infected animals

131:49that come from Southern China most likely.

131:52They all, maybe there's only one of them that's infected,

131:55which how could that possibly be?

131:58And it's only sent to Wuhan.

131:59It's not sent anywhere else,

132:02to any of the markets there or whatever.

132:04And then maybe somebody in a market is infected.

132:06That's one remote possibility, but a possibility.

132:10Another is that researchers

132:13from the Wuhan Institute of Virology

132:15go down to Southern China.

132:17We didn't, we haven't talked about it yet,

132:19but in 2012, there were six miners were sent

132:22into a copper mine in Southern China and Yunnan province.

132:26All of them got very sick

132:28with what now appear like COVID 19 like symptoms.

132:31Half of them died.

132:34Blood samples from them were taken

132:37to the Wuhan Institute of Virology and elsewhere.

132:40And then after that, there were multiple site visits

132:45to that mine, collecting viral samples

132:49that were brought to the Wuhan Institute of Virology,

132:52included among those samples were,

132:55was this now infamous RETG 13 virus,

132:59which is among the genetically closest viruses

133:02to SARS CoV2.

133:03There were other nine other or eight other viruses

133:07that were collected from that mine

133:08that were presumably very similar to that.

133:11And again, we have no access to the information

133:14about those and many of the other,

133:17most, almost all of the other viruses.

133:19So could it be that one of the people

133:24who was sent from the Wuhan Institute of Virology

133:26or the Wuhan Centers for Disease Control,

133:29they went down there to collect

133:31and they got infected asymptomatically and brought it back?

133:34Could it be that they were working on these viruses

133:37in the laboratory and there was an issue

133:40with waste disposal?

133:41And we know that the Wuhan CDC had a major problem

133:45with waste disposal.

133:46And just before the pandemic,

133:48one, they put out an RFP to fix their waste disposal.

133:53And in early 2019, they moved to their new site,

133:59which was basically across the street

134:00from the Huanan Seafood Market.

134:03So could there have been issue of somebody infected

134:06in the lab of waste disposal?

134:08Could a laboratory animal, their experiences

134:10in China, actually China just recently passed a law

134:13saying it's illegal to sell laboratory animals

134:17in the market because there were scientists,

134:19or one scientist who was selling laboratory animals

134:23in the market and people would just come and buy.

134:27It's insane.

134:28So there's so many, there are so many scenarios,

134:31but if I, again, connect it to my 85% number,

134:35I think in the whole category of laboratory related incidents,

134:39whether it's collection, waste,

134:42something connected to the lab,

134:43I think that's the most likely,

134:46but there are other credible people

134:49who would say they think it's not the most likely

134:52and I welcome their views

134:54and we need to have this conversation.

134:55So in your write up, but what's the URL?

134:59Because I always find it by doing Jamie Metzl lab leak.

135:03It's probably the easiest, just Google that.

135:05No, no, but if you just go to jamiemetzl.com,

135:08J A M I E M E T Z L dot com,

135:11then they're just a thing, it's COVID origins.

135:15It's COVID origins.

135:17Or you could just Google Jamie Metzl lab leak.

135:21Google search engine is such a powerful thing.

135:23You mentioned in that write up that you don't think,

135:27this could be just me misreading it

135:29or it's just slightly miswritten,

135:31but you don't think that the virus

135:34is from that 2012 mind, which is fascinating,

135:38could be the backbone for SARS COVID too.

135:40So what I mean, just the specific virus,

135:43which I mentioned, RATG13,

135:45and there's a whole history of that

135:48because it had a different name and it looked,

135:51and Xiaojiang Li provided wrong information

135:54about when it had been sequenced.

135:57I mean, there was a whole issue connected to that.

136:01But the genetic difference,

136:02even though it's 96.2% similar to the SARS COVID2 virus,

136:10that's actually a significant difference,

136:12even though that and a virus called Banal 52

136:17that was collected in Laos are the two most similar,

136:20there still are differences.

136:22So I'm not saying RATG13 is the backbone,

136:25but is there, I believe there is a possibility

136:28that other viruses that were collected

136:32either in that mine in Yunnan in Southern China

136:36or in Laos or Cambodia,

136:39because that was with the EcoHealth Alliance

136:43proposals and documents.

136:45Their plan was to collect viruses

136:48in Laos and Cambodia and elsewhere

136:51and bring them to the Wuhan Institute of Virology

136:54so that there are people.

136:55As a matter of fact, just when I was sitting here

136:57before this interview,

137:01I got a message from somebody who was saying,

137:03well, Peter Daszak is telling everybody

137:06that the viral sample, the Banal 52 from Laos

137:10proves that there's not a lab incident origin

137:13of the pandemic.

137:14And it actually doesn't prove that at all

137:17because these viruses were being collected

137:20in places like Laos and Cambodia

§15Transcript · 2:17:24–2:26:36

137:24and being brought to the Wuhan Institute of Virology.

137:28Those are like early, early, like the prequel.

137:32So these are, they're not sufficiently similar

137:35to be a, to serve as a backbone,

137:37but they kind of tell a story

137:38that they could have been brought to the lab

137:40through several processes, including genetic modification

137:44or through the natural evolution processes,

137:47accelerated evolution, they could have arrived

137:49to something that has the spike protein

137:52and the cleavage, the foreign cleavage site

137:56and all that kind of stuff.

137:56So what I'm saying is the essential point

138:00is if we had access, if we knew everything

138:03that was being, every virus that was being held

138:05at the Wuhan Institute of Virology and the Wuhan CDC,

138:09we had full access.

138:10We had full access to everybody's lab notes.

138:13And we did just the kind of forensic investigation

138:16that has been so desperately required since day one.

138:21We'd be able to say, well, what did you have?

138:24Because if we knew, if it should come out,

138:26that the Wuhan Institute of Virology had in its repository,

138:30prior to the outbreak, either SARS CoV2

138:34or a reasonable precursor to it,

138:36that would prove the lab incident hypothesis.

138:39In my mind, that's almost certainly why they are preventing

138:42any kind of meaningful investigation.

138:46So my hypothesis is not that what RITG13 says

138:51is because as I mentioned earlier,

138:54the genetics of virus are constantly recombinating.

138:59So that what that means is if you have,

139:01you don't have very many total outlier viruses

139:06in a bat community because these viruses

139:08are always mixing and matching with each other.

139:11And so if you have RITG13, which is relatively similar

139:16to SARS CoV2, there's a pretty decent likelihood

139:19there was other stuff that was collected

139:22at this mine called Mojang Mine in Yunnan Province,

139:28maybe in Laos and Cambodia.

139:30And that's why we need to have that information.

139:36Do you think somebody knows who patient zero is

139:39within China?

139:39So do you think that is?

139:40Well, there's two things.

139:42One is I think somebody and people probably know.

139:45And then two, it's been incredibly curious

139:47that the best virus chasers in the world are in China.

139:52And they are in Wuhan.

139:54And when we can talk about this deeply compromised,

139:58now vastly improved World Health Organization process.

140:03But when they went there, the Chinese,

140:05the local and national Chinese authorities say,

140:07oh, we haven't done, we haven't tested the samples

140:10in our blood center.

140:11We haven't done any of this tracing.

140:13And these deeply compromised people

140:16who were part of the international part

140:20of the joint study tour, when they came out with their,

140:25they had their visit earlier this year

140:26and came out with their report.

140:28They had in my mind, just an absurd letter

140:32to the editor in nature saying,

140:34well, if we don't hurry back,

140:35we're not gonna know what happened.

140:37Assuming that the people in China are like bumpkins

140:41who on their own don't know how to trace the origin

140:44of a virus and the opposite is the case.

140:47So I think there are people in China

140:50who at least know a lot.

140:51They know a lot more than they're saying.

140:55And at the best case scenario is the Chinese government

140:59wants to prevent any investigation, including by them.

141:03The worst case scenario is that there are people

141:06who already know.

141:07And that's why, again, my point from day one has been,

141:10we need a comprehensive international investigation

141:14in Wuhan with full access to all relevant records,

141:18samples and personnel.

141:19When this, again, deeply flawed.

141:22Can I give you a little history of this WHO process?

141:27Okay.

141:28Who are the, that's funny.

141:32Who's on first?

141:33Who's on first?

141:34I'm so funny with the jokes.

141:36Look at me go.

141:38Who are the WHO?

141:39So what is this organization?

141:41What is its purpose?

141:43What role did it play in the pandemic?

141:45It certainly was demonized in the realm of politics.

141:49This is an institution that was supposed to save us

141:55from this pandemic.

141:57A lot of people believe it failed.

141:58Has it failed?

142:00Why did it fail?

142:01And you said it's improving.

142:02How is it improving?

142:04Great.

142:05All right.

142:05I hope you don't mind.

142:06I'm gonna have to talk for a little bit of extra time.

142:08I love this.

142:09I love this.

142:10Good, good, good, good.

142:12So the WHO is an absolutely essential organization

142:16created in 1948 in that wonderful period

142:20after the Second World War

142:22when the United States and allied countries

142:24asked the big bold questions,

142:27how do we build a safer world for everyone?

142:30And so that's the WHO.

142:33If we, although there are many critics of the WHO,

142:36if we didn't have it, we would need to invent it

142:39because the whole nature of these big public health issues

142:44and certainly for pandemics, but all sorts of things

142:48is that they are transnational in nature.

142:50And so we cannot just build moats.

142:54We cannot build walls.

142:55We're all connected to it.

142:56So that's the idea.

142:59There's a political process because the United Nations

143:02and the WHO is part of it,

143:06it exists within a political context.

143:08And so the current director general

143:11of the World Health Organization

143:13who was just reelected for his second five year term

143:16is Dr. Tedros Adhanom Ghebreyesus

143:20who is from Ethiopia, Tigrayan from Ethiopia.

143:25And in full disclosure, I have a lot of respect for Tedros.

143:31Tedros got his job.

143:33He was not America's candidate.

143:35He was not Britain's candidate.

143:37Our candidate was a guy named David Nabarro

143:39who I also know and have tremendous respect for.

143:43China led the process of putting Tedros in this position.

143:50And in the earliest days of the pandemic,

143:54Tedros, in my view,

143:55even though I have tremendous respect for him,

143:57I think he made a mistake.

143:59The WHO doesn't have its own

144:02independent surveillance network.

144:04It's not organized to have it

144:05and the states have not allowed it.

144:07So it's dependent on member states

144:10for providing it information.

144:13And because it's a poorly funded organization

144:17dependent on its bosses who are these governments,

144:20it's natural instinct isn't to condemn its bosses.

144:24It's to say, well, let's quietly work with everybody.

144:28Having said that,

144:29the Chinese government knowingly lied to Tedros.

144:33And Tedros, in repeating the position

144:36of the Chinese government,

144:37which incidentally I'll say Donald Trump

144:39also did the exact same thing.

144:41Donald Trump had a private conversation with Xi Jinping

144:43and then repeated what Xi had told him.

144:48Both of them were wrong.

144:51Dr. Tedros, I think when Chinese government was lying,

144:55knowingly lying,

144:56saying there's no human to human transmission,

145:00Dr. Tedros said that.

145:01And even though within the World Health Organization,

145:04there were private critiques saying

145:07China is now doing exactly what it did in SARS one,

145:10it's not providing access,

145:11it's not providing information.

145:13Tedros's instinct because of his background,

145:16because of his role and wrongly,

145:21was to have a more collaborative relationship with China,

145:25particularly by making assertions

145:28based on the information that was wrong.

145:30Don't call people liars,

145:32they're not gonna be happy with you.

145:33They're not gonna be happy.

145:34And the job of the WHO isn't to condemn states,

145:38it's to do the best possible job of addressing problems.

145:41And I think that the culture was,

145:43well, let's do the most that we can.

145:45If we totally alienate China on day one,

145:49we're in even worse shape than if we call them out for.

145:52Not exactly sure, by the way,

145:54that maybe you can also steel man that argument.

145:58Like it's not completely obvious that that's

146:00a terrible decision.

146:02Like if you and I were in that role,

146:05we wouldn't make that decision.

146:06It's complicated because like,

146:09you want China on your side to help solve this.

146:11So I would have made a different decision,

146:14which is why I never would have been selected

146:17as the director general.

146:18There's a selection criteria

146:20that everybody kind of needs to support you.

146:24And so, but let me just, this is just the beginning.

146:27Can you also just elaborate or kind of restate,

146:30what were the inaccuracies that you quickly mentioned?

146:34So human to human transmission, what were the things?

§16Transcript · 2:26:36–2:36:27

146:36So the most important, there were a few things.

146:41One, China didn't report the outbreak.

146:46Two, they had the sequenced genome

146:49of the SARS CoV2 virus,

146:51and they didn't share it for two critical weeks.

146:55And when they did share it, it was inadvertent.

146:59I mean, there was a very, very courageous scientist

147:01who essentially leaked it and was later punished

147:04for leaking it, even though the Chinese government

147:06is now saying we were so great by releasing the sequenced.

147:09Wait, I was really confused.

147:10Really?

147:11So I'm so clueless about this as most things.

147:15Because I thought, because there was a celebration of,

147:19isn't this amazing that we got the sequence,

147:23that's amazing, and then the scientific community

147:27across the world stepped up and were able to do

147:30a lot of stuff really quickly with that sharing.

147:32Because I thought the Chinese government shared it.

147:34No, no, so they sat on it for two weeks.

147:37When they shared it against their will, it was incredible.

147:40Moderna, 48 hours later after getting the information,

147:45getting the sequenced genome, they had the formulation

147:48for what's now the Moderna COVID 19 vaccine.

147:51But that's two critical weeks.

147:55In those early days, they blocked the World Health

147:59Organization from sending its experts to Wuhan

148:03for more than three weeks.

148:04I said they lied about human to human transmission.

148:08During that time, they were aggressively enacting

148:11their coverup, destroying records, hiding samples,

148:15imprisoning people who were asking tough questions.

148:19They soon after established their gag order.

148:24They fought internally in the World Health Organization

148:27to prevent the declaration of a global emergency.

148:32So China definitely, I mean, I couldn't be stronger

148:36in my critique of China, particularly what it did

148:40in those early days, but it really, what it's doing

148:42even to today is outrageous.

148:44So that was, so then there was the question of,

148:48well, how do we examine what actually happened?

148:51And the Prime Minister of Australia then and now,

148:54Scott Morrison, was incredibly courageous.

148:57And he said, we need a full investigation.

148:59And because of that, the Chinese government

149:02attacked him personally and imposed trade sanctions

149:05on Australia to try to, not just to punish Australia,

149:09but to deliver a message to every other country.

149:12If you ask questions, we're going to punish you ruthlessly.

149:15And then that certainly was the message that was delivered.

149:21The Australians brought that idea of a full investigation

149:24to the World Health Assembly in May of 2020.

149:28As I mentioned before, the WHA is the governing authority

149:32above, of states above the World Health Organization.

149:36And so, but instead of passing a resolution calling

149:40for a full investigation, what ended up ironically

149:44and tragically passing with Chinese support

149:48was a mandate to have essentially

149:50a Chinese controlled joint study,

149:54where half of the team, a little more than half of the team

149:56was Chinese experts, government affiliated Chinese experts,

149:59and half were independent international experts

150:04but organized by the WHO.

150:08And then it took six months

150:10to negotiate the terms of reference.

150:12And again, while China was doing all this coverup,

150:14they delayed and delayed and delayed.

150:16And by the terms of reference that were negotiated,

150:19China had veto power over who got to be a member

150:22of the international group.

150:25And that group was not entitled to access to raw data.

150:31The Chinese side would give them conclusions

150:34based on their own analysis of the raw data,

150:37which was totally outrageous.

150:39So then, and I was a big, I and others,

150:43now friend of mine, although we've never met in person,

150:46Gilles de Manouf in New Zealand,

150:48he did a great job of chronicling just the letter by letter

150:51of the terms of reference.

150:54So then it took, now it's the January of this year,

150:59January, 2021, this deeply flawed,

151:02deeply compromised international group is sent to Wuhan.

151:07So what's the connection between this group

151:09and the joint study?

151:10So the joint study, it had the Chinese side

151:12and the international side.

151:13So these international experts,

151:15then part of their examination was going

151:18for one month to Wuhan.

151:19And the nature of the flaws of this international group.

151:23It's okay, really important point.

151:24And I'm sorry, I wasn't clear on that.

151:26Rather, the mandate of what they were doing

151:31was not to investigate the origins of the pandemic.

151:34It was to have a joint study

151:37into the zoonotic origins of the virus,

151:40which means, which was interpreted to mean

151:43the natural origins hypothesis.

151:45They weren't empowered for a single hypothesis,

151:48not so that they weren't empowered

151:51to examine the lab incident origin.

151:54They were there to look at the natural origin hypothesis.

151:56To shop for some meat at some markets.

151:58Yeah, so that was, so then they were there for a month.

152:03Yeah.

152:04So out of the makeup of the team, guess who was?

152:09So the United States government proposed three experts

152:12for this team.

152:13People who had a lot of background.

152:15This was the Trump administration.

152:17People who had a lot of background,

152:19including in investigating lab incidents.

152:23None of those people were accepted.

152:24The one American who was accepted.

152:27Don't tell me it's Peter Daszak.

152:28Peter Daszak.

152:29Peter Daszak, who had this funding relationship

152:33for many years with the Wuhan Institute of Virology,

152:35whose entire basically professional reputation

152:39was based on his collaboration with Shujang Li,

152:43who had written the February, 2020 Lancet letter

152:47saying it comes from natural origin.

152:49And anybody who's suggesting otherwise

152:51is a conspiracy theorist.

152:53And who, at least according to me,

152:55had been at very, very least the opposite of transparent

153:00and at most engaged in a massive disinformation campaign.

153:03He is the one American who's on this.

153:07So they go there, they have one month in Wuhan.

153:10Two weeks of it are spent in quarantine

153:14just in their hotel rooms.

153:15So then they have two weeks,

153:17but really it's just 10 working days.

153:20One of the earliest, and so then they're kind of,

153:22we've all seen the pictures.

153:23They're traveling around Wuhan in little buses.

153:27One of the first visits they have

153:30is to this museum exhibition on the,

153:33it's basically a propaganda exhibition on the success,

153:37Xi Jinping and the success in fighting COVID.

153:40And they said, well, we had to show respect

153:41to our Chinese hosts.

153:42But I think what the Chinese hosts were saying is,

153:44let's just, I'm just gonna rub your noses in this.

153:47You're gonna go where we tell you.

153:48You're gonna hear what we want you to hear.

153:53So they have that little short time.

153:54They spend a few hours.

153:56They weren't in control of where the bus goes.

153:59No, I mean, they made recommendations.

154:01Many of their recommendations were accepted,

154:05but like when they went to the Wuhan Institute of Virology

154:08and some of them did,

154:10they weren't able to do any kind of audit

154:13when they asked for access to raw data.

154:15They weren't provided that.

154:18They were, it was, as I said in my 60 minutes interview,

154:22it was a chaperoned study tour.

154:24It was not even remotely close to an investigation.

154:27And the thing they were looking at

154:29wasn't the origins of the pandemic.

154:32It was the single hypothesis

154:34of a quote unquote natural origins.

154:39Then, I mean, it was really so shocking for me.

154:43On February 9 of this year in Wuhan,

154:46the Chinese government sets up a joint press event

154:51where it's the Chinese side and the international side.

154:55And during that press event,

154:58a guy named Peter Ben Embarek,

154:59and it's a little confusing.

155:00He was basically the head of this delegation

155:04and he works for the WHO,

155:06even though this was an independent committee,

155:09it was organized by the WHO.

155:11So Peter Ben Embarek gets up there and says,

155:16we think it's most likely it comes from nature.

155:19Then he says, we think it's possible

155:22it comes through frozen food,

155:23which is absolutely outrageous.

155:25I mean, it's basically preposterous.

155:27Alena Chan calls this popsicle origins,

155:32but it's really, really unlikely.

155:34But then most significantly,

155:36he says that we've all agreed

155:40that a lab incident origin is quote unquote

155:43extremely unlikely and shouldn't be investigated.

155:47We later learned that the way they came up

155:50with that determination was by a show of hands vote

155:54of the international experts and the Chinese experts.

155:57And the Chinese experts had to do their vote

156:00in front of the Chinese government officials

156:03who were constantly there.

156:05So even if whatever they thought,

156:07there was no possibility that someone raises their hand

156:09and say, oh yeah, I think it's a lab origin.

156:12So that was outrageous thing number one.

156:15Outrageous thing number two,

156:16which I mean, I'll come back to my response in February.

156:21Outrageous thing number two is months later,

156:24Peter Benambarak does an interview on Danish television.

§17Transcript · 2:36:27–2:47:11

156:27And he says, actually I was lying about extremely unlikely

156:32because the Chinese side,

156:34they didn't want any mention of a lab incident origin

156:38anywhere including in the report that later came out.

156:42And so the deal we made, even though he himself thought

156:46that at least some manifestation of a lab incident origin

156:49was likely and that there should be an investigation,

156:53particularly he said, well, that's kind of weird

156:54that the Wuhan CDC moved just across

156:57from the Huanan seafood market

156:59just before the beginning of the pandemic.

157:03But he said as a horse trading deal

157:06with the Chinese authorities,

157:08it shouldn't be that he agreed to say

157:12it was extremely unlikely and shouldn't be investigated.

157:15So I was in actually in Colorado staying with my parents

157:18and I stayed up late watching this press event.

157:23And I was appalled because I knew after two weeks

157:25there was no way they could possibly come to that conclusion.

157:29So I immediately sent a private message to Tedros,

157:33the WHO director general, essentially saying

157:37there's no way they had enough access

157:40to come to this conclusion.

157:42If the WHO doesn't distance itself from this,

157:47the WHO itself is going to be in danger

157:49because it's going to be basically institutional capture

157:53by the Chinese.

157:54This was repeating the Chinese government's

157:56propaganda points.

157:57And Tedros sent me a really, again,

158:00why I have so much respect for Tedros,

158:02sent me a private note saying,

158:04don't worry, we are determined to do the right thing.

158:08And so I got that private message.

158:10And again, I really like Tedros,

158:11but I thought, well, what are you gonna do?

158:14Three days later, Tedros makes a public statement.

158:19And he says, I've heard this thing.

158:23I don't think that this is a final answer.

158:25We need to have a full investigation into this process.

158:29He then released two more statements

158:32saying we need to have a full investigation

158:37with access to raw data.

158:38And we need a full audit of the Wuhan labs.

158:42So then that part was really, really great.

158:46But then this saga continues because,

158:49so I was part of a group, as I mentioned before,

158:51this Paris group.

158:53It was about two dozen or so experts.

158:55And we'd been meeting since 2020 and having regular meetings.

159:00And we just present papers, present data,

159:02debate to try to really get to the bottom of things.

159:04And it was all private.

159:06So I went to this group and I said, look,

159:09this playing field is now skewed.

159:12These guys, they've put out this thing,

159:14lab incident origin, extremely unlikely.

159:16It's in every newspaper in the world.

159:19We can't just be our own little private group

159:21talking to each other.

159:23So I led the political process of drafting

159:26what became four open letters that many of us signed,

159:31most of us signed, that saying, all right,

159:35here's why this study group and the report are not credible.

159:41Here's what's wrong.

159:42Here's what a full investigation would look like.

159:45Here's a treasure map of all the resources

159:48where people can look.

159:50And we demand a comprehensive investigation.

159:52So those four open letters were in pretty much

159:56every newspaper in the world.

159:58And it played a really significant role

160:00along with some other things.

160:02There was later, there was a letter, a short letter

160:05in Science making basically similar points

160:10in a much more condensed way.

160:11There were some higher profile articles

160:14by Nicholas Wade and Nick Baker and others.

160:19And those collectively shifted the conversation.

160:24And then really impressively, the WHO,

160:29and with Tedros's leadership, did

160:30something that was really incredible.

160:33And that is earlier this year, they,

160:36meaning the leadership of the WHO, not the World Health

160:39Assembly, but the leadership of the WHO,

160:43announced the establishment of what's

160:45called SAGO, the Scientific Advisory Group on the Origins

160:49of Novel Pathogens.

160:51And basically what they did was overrule their own governing

160:55board and say, we're going to create our own entity.

160:59So it basically dissolved that international, deeply flawed

161:03international joint study group.

161:04And a lot of those people, they have become very critical,

161:07like the Chinese of Tedros.

161:11So then they had an open call for nominations

161:15to be part of SAGO.

161:17And so a lot of people put in their nominations.

161:23They selected 26 people.

161:25But our group, we had a meeting, and we

161:27were unhappy with that list of 26.

161:30It still felt skewed toward the natural origin hypothesis.

161:35So again, I drafted, and we worked on together,

161:38an open letter which we submitted to the WHO saying,

161:42we think this list, it's a step in the right direction,

161:45but it's not good enough.

161:46And we call on these three people to be removed,

161:50and we have these three people who we think should be added.

161:53Incredibly, and I was in private touch

161:56with the WHO, after announcing the 26 people,

162:00the WHO said, we're reopening the process, so send in more.

162:04And so then they added two more people, one of whom

162:08is an expert in the auditing of lab incidents.

162:13And then one of the, so they added those two.

162:17And then when they just released the list of people

162:20who are part of SAGO, this one woman,

162:23a highly respected Dutch virologist named Marion Koopmans,

162:26who had been part of that deeply flawed and compromised

162:30international study group, who had called,

162:33who has consistently called a lab incident origin, quote,

162:36unquote, a debunked conspiracy theory.

162:39As of now, her name is not on the list.

162:42We haven't seen any announcements.

162:44So I summary, and I'm sorry to go on for so long

162:48and to be so animated about this,

162:49I genuinely feel that the WHO is trying to do the right thing.

162:55But they exist within a political context.

162:59And they're pushing at the edges,

163:03but there's only so far that they can go.

163:07And that's why we definitely need

163:10to have full accountability for the WHO.

163:12We need to expand the mandate to WHO.

163:14But we need to recognize that states have a big role.

163:18And China is an incredibly influential state

163:21that's doing everything possible to prevent

163:24the kind of full investigation into pandemic origins

163:27that's so desperately required.

163:28Well, it sounds like the leadership

163:31made all the difference in the WHO.

163:34So like the way to change the momentum of large institutions

163:37is through the leadership.

163:38Leadership and empowerment, as I mentioned,

163:42the World Health Assembly is meeting now.

163:45And I think that it shouldn't be that we require superhumans.

163:50And there are some people who are big critics of WHO.

163:53The leader of the WHO in SARS 1 was definitely more aggressive.

164:00She had a different set of powers at that time.

164:05But it can't be entirely, we definitely

164:08need strong willed, aggressive, independent people

164:12in these kinds of roles.

164:14We also need a more empowered WHO.

164:17Like when the Chinese government in the earliest days

164:20of the pandemic said, we're just not

164:23going to allow you to send a team to collect

164:26your own information.

164:27And we're not going to allow you to have

164:30any kind of independent surveillance,

164:34there was very little that the WHO could do because

164:38of the limitations of its mandate.

164:40And we can't just say we're going to have a WHO that only

164:44compromises Chinese sovereignty.

164:46If we want to have a powerful WHO,

164:48we should say we have emergency teams when the director

164:54general says an emergency team needs to go somewhere.

164:57If they aren't allowed to go there that day,

165:00you could say there's an immediate referral

165:02to the Security Council.

165:03There needs to be something.

165:05But we have all these demands, rightfully,

165:09so of the WHO, which doesn't have the authorities.

165:13The WHO itself only controls 20% of its own budget.

165:16So the governments are saying, we're

165:17going to give you money to do this or that.

165:21So we need a stronger WHO to protect us,

165:27but we also have to build that.

165:28So looking a little bit into the future,

165:33let's first step into the past, sort

165:35of the philosophical question about China.

165:39If you were to put yourself in the shoes of the Chinese

165:43government, if they were to be more transparent,

165:49how should they be more transparent?

165:51Because it's easier to say, we want to see this.

165:57But from a perspective of government,

165:59and not just the Chinese government,

166:00but a government on WHO's geographic territory,

166:07say it's a lab leak, a lab leak occurred

166:11that has resulted in trillions of dollars of loss,

166:16countless of lives, just all kinds of damage to the world.

166:24If they were to admit or show data

166:27that could serve as evidence for a lab leak,

166:31that's something that people could, in the worst case,

166:35start wars over, or in the most likely case,

166:41just constantly bring that up at every turn,

166:45making you powerless in negotiations.

166:50Whenever you want to do something

166:51in geopolitical sense, the United States

166:54will bring up, oh, remember that time

166:57you cost us trillions of dollars because of your fuck up?

167:01So what is the incentive for the Chinese government

167:05to be transparent?

167:07And if it is to be transparent, how should it do it?

§18Transcript · 2:47:11–2:56:44

167:11So there's a bunch of people.

167:14The reason I'm talking to you, as opposed

167:17to a bunch of other folks, because you

167:19are kindhearted and thoughtful and open minded

167:22and really respected.

167:24There's a bunch of people that are talking about lab leak

167:27that are a little bit less interested in building

167:31a better world and more interested in pointing out

167:34the emperor has no clothes.

167:36They want step one, which is saying, basically,

167:40tearing down the bullshitters.

167:43They don't want to do the further steps of building.

167:48And so as the Chinese government,

167:50I would be nervous about being transparent with anybody that

167:53just wants to tear our power centers, our power

167:58structures down.

167:59Anyway, that's a long way to ask,

168:01how should the Chinese government be transparent now

168:06and in the future?

168:08So maybe I'll break that down into a few sub questions.

168:12The first is, what should, in an ideal world,

168:15what should the Chinese government do?

168:17And that's pretty straightforward.

168:20They should be totally transparent.

168:22The South African government now,

168:24there is an outbreak of this Omicron variant.

168:27And the South African government has done what we would want.

168:31A government to do is say, hey, there's an outbreak.

168:33We don't have all of the information.

168:35We need help.

168:36We want to alert the world.

168:38And in some ways, they're being punished for it

168:41through these travel bans.

168:42But it's a separate topic.

168:43But I actually think short term travel bans actually

168:46are not a terrible idea.

168:49They should have, on day one, they

168:51should have allowed WHO experts in.

168:55They should have shared information.

168:57They should have allowed a full and comprehensive

169:00investigation with international partnerships

169:04to understand what went wrong.

169:07They should have shared their raw data.

169:10They should have allowed their scientists

169:12to speak and write publicly.

169:14Because nobody knows more about this stuff,

169:17certainly in the early days, than their scientists do.

169:20So it's relatively easy to say what they should do.

169:26It's a hard question to say, well, what would happen?

169:29Let's just say tomorrow, we prove for certain

169:35that this pandemic stems both from an accidental lab

169:38incident and then from what I've consistently

169:40called a criminal cover up.

169:42Because the cover up has done, in many ways,

169:46as much or more damage than the incident.

169:49Well, what happens?

169:50You could easily imagine Xi Jinping has had two terms

169:54as the leader of China.

169:57And he can now have unlimited terms.

169:59Well, they've changed the rules for that.

170:01But he's got a lot of enemies.

170:03I mean, there are a lot of people who are waiting in line

170:06to step up.

170:07So is there a chance that Xi Jinping could be deposed

170:11if it was proven that this comes from a lab?

170:13And I think there's a real possibility.

170:15Would people in the United States Congress, for example,

170:19demand reparations from China?

170:21So we've had $4.5 trillion of stimulus,

170:26all of the economic losses, and we owe a lot of money

170:29to China from our debt.

170:32I'm quite certain that members of Congress

170:35would say, we're just going to wipe that out.

170:37It would destroy the global financial system,

170:39but I think they would be extremely likely.

170:42Would other countries, like India,

170:44that have lost millions of people

170:47and had terrible economic damages,

170:50would they demand reparations?

170:53So I think from a Chinese perspective,

170:55starting from now, it would have

170:58major geopolitical implications.

171:00And go back to Chernobyl, there was

171:03a reason why the Soviet Union went to such length

171:06to cover things up.

171:08And when it came out, I mean, there are different theories,

171:11but certainly Chernobyl played some role

171:15in the end of communist power in the Soviet Union.

171:21So the Chinese are very, very aware of that.

171:25But the difference, of course, with Chernobyl,

171:27the damage to the rest of the world

171:28was not nearly as significant as it was with COVID.

171:32So you say that the coverup is a crime,

171:34but everything you just described,

171:37the response of the rest of the world,

171:40is, I could say, unfair.

171:45Well, it's not...

171:46So, okay, if we say the best possible version of the story,

171:50you know, lab leaks happen, they shouldn't happen,

171:55but they happen.

171:57And how is that on the Chinese government?

172:02I mean, what's a good example?

172:04Well, the Union Carbide.

172:05Union Carbide, there was this American company

172:07operating in India, they had this leak,

172:10all these people were killed.

172:12The company admitted responsibility.

172:15I was working in the White House

172:17when the United States government, in my view,

172:19which I know to be the case,

172:20but other people in China think differently,

172:23bombed the Chinese embassy in Belgrade.

172:25And so the United States government

172:27allowed a full investigation,

172:29then we paid reparations to the families.

172:34And so to your question, if I were,

172:36let's just say I were the Chinese government,

172:39not, I mean, kind of an idealized version

172:42of the Chinese government.

172:43And let's just say that they had come to the conclusion

172:46that it was a lab incident.

172:49And let's just say they knew that even if

172:52they continued to cover it up,

172:55eventually this information would come out.

172:58I mean, maybe there was a whistleblower,

173:00maybe they knew of some evidence

173:01that we didn't know about or something.

173:05What would I do starting right now?

173:09What I would do is I would hold a press conference

173:12and I would say, we had this terrible accident.

173:16The reason why we were doing this research

173:19in Wuhan and elsewhere is that we had SARS one

173:23and we felt a responsibility to do everything possible

173:26to prevent that kind of terrible thing happening again

173:29for our country and for the world.

173:31That was why we collaborated with France,

173:34with the United States in building up those capacities.

173:38We know that nothing is perfect,

173:40but we're a sovereign country and we have our own system.

173:42And so we had to adapt our systems

173:45so that they made sense internally.

173:49When this outbreak began, we didn't know how it started.

173:53And that was why we wanted to look into things.

173:57When the process of investigating became so political,

174:01it gave us pause and we were worried that our enemies

174:04were trying to use this investigation

174:07in order to undermine us.

174:09Having said that, now that we've dug deeper,

174:13we have recognized because we have access

174:16to additional information that we didn't have then,

174:19that this pandemic started from an accidental lab incident.

174:23And we feel really terribly about that.

174:25And we know that we were very aggressive

174:28in covering up information in the beginning,

174:31but the reason we were doing that is because we thoroughly,

174:34we fully believe that it came from a natural origin.

174:37Now that we see otherwise, we feel terribly.

174:41Therefore, we're doing a few different things.

174:44One is we are committing ourselves

174:48to establishing a stronger WHO, a new pandemic treaty

174:54that addresses the major challenges that we face

174:57and allows the World Health Organization

175:00to pierce the veil of absolute sovereignty

175:03because we know that when these pandemics happen,

175:06they affect everybody.

175:08We are also putting, and you can pick your number,

175:11but let's start with five trillion US dollars,

175:15some massive amount, into a fund

175:19that we will be distributing to the victims of COVID 19

175:24and their, and their.

175:26China would do that?

175:27This is a fantasy speech.

175:29But I disagree with your, I mean, okay.

175:34So you think China has a responsibility?

175:36Well, so it's not the, like just a lab leak.

175:40Like if China on day one had said we have this outbreak,

175:45we don't know where it came from,

175:47we want to have a full investigation,

175:50we call on international,

175:52responsible international partners

175:53to join us in that process,

175:55and we're going to do everything in our power

175:58to share the relevant information

176:00because however this started, we're all victims.

176:03That's a totally different story

176:05than punishing Australia, preventing the WHO,

176:08blocking any investigation,

176:10condemning people who are trying to look, and so that's.

176:13So cover up for a couple weeks,

176:16you can understand maybe,

176:18because there's so much uncertainty.

176:20You're like, oh, let's hide all the Winnie the Pooh pictures

176:24while we figure this out.

176:26But the moment you really figure out what happened,

176:30you always, as a Jew I can say this,

176:32always find like a blame the Jews kind of situation

176:35a little bit, just a little bit.

176:36Be like, all right, it's not us.

176:38I'm just kidding.

176:41But be proactive in saying.

§19Transcript · 2:56:44–3:06:40

176:44Just to start here, but the joke about that is

176:47there's a big problem because a lot of people

176:50have to leave the Jewish socialist conspiracy

176:53to make it for the Jewish capitalist conspiracy meeting.

176:56I love it.

176:59So I would say not five trillion,

177:01but some large amount,

177:03and I would really focus on the future,

177:05which is every time we talk about the lab leak,

177:09the unfortunate thing is I feel like people

177:11don't focus enough about the future.

177:13To me, the lab leak is important

177:16because we want to construct a kind of framework

177:20of thinking and a global conversation

177:23that minimizes the damage done by future lab leaks,

177:28which will almost certainly happen.

177:30And so to me, any lab leak is about the future.

177:35I would launch a giant investment in saying

177:40we're going to create a testing infrastructure,

177:43like all of this kind of infrastructure investments

177:46that help minimize the damage of a lab leak

177:49here and the rest of the world.

177:51So the challenge with that is one,

177:54it's hard to imagine a fully accountable future system

177:58to prevent these kinds of terrible pandemics

178:01that's built upon obfuscation and coverup

178:06regarding the origins of this worst pandemic in a century.

178:09So it's just like that foundation isn't strong enough.

178:14Second, China across the fields of science

178:17is looking to leapfrog the rest of the world.

178:20So China now has current plans to build BSL4 labs

178:25in every of its province.

178:27Yeah, they're scaling up the.

178:28Scaling up everything ends up with the plan on leading.

178:32And that's why, again, I was saying before,

178:33I think there's a lot of similarity between this story,

178:36at least as I see it, at least the most probable case,

178:40and these other areas where China gets knowledge

178:42and then tries to leapfrog.

178:44It's the same with AI and autonomous killer robots.

178:48It's the same with human genome editing,

178:50with animal experimentations, with so many,

178:52basically all areas of advanced science.

178:58So the question is, would China stop in that process?

179:01And then third, it's a little bit

179:05of a historical background,

179:07but defending national sovereignty

179:10is one of the core principles of,

179:13certainly of the Chinese state.

179:16And the historical issue is,

179:18for those of us who come from the West,

179:21I mean, one of the lessons of the postwar planners

179:24was that absolute national sovereignty

179:26was actually a major feeder

179:29into the first and second world wars,

179:31that we had all these conflicting states.

179:34And therefore the logic of the postwar system

179:37is we need to in some ways pool sovereignty

179:39that's like the EU and have transnational organizations

179:44like the UN organizations

179:46and the Bretton Woods organizations.

179:47For most Asian states,

179:49and also even for some African,

179:51and the people who were kind of

179:52on the colonized side of history,

179:55sovereignty was the thing that was denied them.

179:58That was the thing that they want,

180:00that the European power is denied.

180:01And so the idea of giving up sovereignty

180:04was the absolute opposite.

180:07And so that's why China is,

180:10and again, I mentioned this Rush Doshi book.

180:12It's not that China is trying to strengthen

180:15this rules based international order,

180:17which is based on the principle

180:19that while there are certain things that we share

180:21and how do we build a governance system

180:23to protect those things,

180:25what it seems to be doing is trying

180:27to advance its own sovereignty.

180:31And so I think I agree with you,

180:33but I don't think that we can just go forward

180:37without some accountability for the.

180:39So the coverup was a big problem.

180:41It's like, I often,

180:44I find myself playing devil's advocate

180:46because I'm trying to sort of empathize

180:49and then I forget that like two or three people

180:54listen to this thing and then they're like,

180:55look, Lex is defending the Chinese government

180:58with their coverup.

180:59No, I'm not, I'm just trying to understand.

181:05I mean, it's the same reason I'm reading Mein Kampf now

181:08is like you have to really understand the minds of people

181:13as if I too could have done that.

181:18You know, you have to understand

181:19that we're all the same to some degree

181:22and that kind of empathy is required

181:25to figure out solutions for the future.

181:29It's just in empathizing with the Chinese government

181:32in this whole situation,

181:35I'm still not sure I understand

181:38how to minimize the chance of a coverup in the future,

181:41whether for China or for the United States.

181:44If the virus started in the United States,

181:45I'm not exactly sure we would be

181:49with all the emphasis we put on freedom of speech,

181:52with all the emphasis we put on freedom of the press

181:57and access to the press,

182:00the sort of all aspects of government.

182:02I'm not sure the US government

182:04wouldn't do the similar kind of coverup.

182:06Let me put it this way.

182:07So we're in Texas now doing this interview.

182:09Imagine there's a kind of horseshoe bat

182:13that we'll call the Texas Horseshoe Bat and the Texas.

182:18There's a lot of bats in Austin,

182:19but it's a whole thing. It's true, it's true.

182:21And so let's just say that the Texas Horseshoe Bats

182:25only exist in Texas, but in Montana,

182:30we have a thing, it's called

182:32the Montana Institute of Virology.

182:36And at the Montana Institute of Virology,

182:38they have the world's largest collection

182:41of Texas Horseshoe Bats, including horseshoe bats

182:45that are associated with a previous global pandemic

182:51called the Texas Horseshoe Bat pandemic.

182:55And let's just say that people in Montana,

182:58in the same town where this

183:00Montana Institute of Virology is,

183:03start getting a version of this

183:06Texas Horseshoe Bat syndrome

183:09that is genetically relatively similar

183:13to the outbreak in Texas.

183:15There are no horseshoe bats there.

183:18And the government says, it's your same point,

183:21Alina's point about the unicorns,

183:23like nothing to see here, just move along.

183:28Would Joe Rogan and Brett Weinstein and Josh Rogan,

183:34would they say, oh, I guess, I just think that.

183:36No, no, but the point is the government going to say it.

183:40So, Joe Rogan is a comedian.

183:45Brett Weinstein is a podcaster.

183:48The point is, what we want is not just those folks

183:53to have the freedom to speak, that's important.

183:56But you want the government to have the transparent,

183:58like, I don't think Joe Rogan is enough

184:02to hold the government accountable.

184:04I think they're going to do their thing anyway.

184:06But I think that's our system,

184:09and that was the genius of the founding fathers.

184:12Is that enough?

184:13That the government probably is going to have

184:16a lot of instincts to do the wrong thing.

184:18That was the experience in England before.

184:22And so that's why we have free speech,

184:25to hold the government accountable.

184:27I mean, I'm kind of broadly a gun control person,

184:30but the people who say, well,

184:31we need to have broad gun rights.

184:34As somebody who's now in Texas, I am offended.

184:39But their argument is, look,

184:40we don't fully trust the government.

184:42If the government, just like we fought against the British,

184:47if the government's wrong,

184:48we want to at least have some authority.

184:51So that's our system, is to have that kind of voice.

184:53And that is the public voice actually balances.

184:57Because every government, as you correctly said,

185:00every government has the same instincts.

185:02And that's why we have, and it's imperfect here,

185:06but kind of these ideas of separation of powers,

185:08of inalienable rights, so that we can have,

185:11it's almost like a vast market where we can have balance.

185:14So you think if a lab leak occurred in the United States,

185:18what probability would you put some kind of public report

185:24led by Rand Paul would come out saying this was a lab leak?

185:29You have good confidence that that would happen?

185:31I have pretty decent confidence.

185:32And the reason I say, I mentioned that I'm a,

185:35I think of myself, I'm sure I'm not anymore,

185:37because as I get older, but as a progressive person,

185:39I'm a Democrat and I worked in Democratic administrations,

185:44worked for President Clinton on the National Security Council.

185:47But my kind of best friend in the United States Senate,

185:52who I talk to all the time,

185:55is a Senator from Kansas named Roger Marshall.

185:59And Roger, I mean, if you just lined up our positions

186:03on all sorts of things, we're radically different.

186:08But we have a great relationship.

186:11We talk all the time and we share a commitment to saying,

186:16well, let's ask the tough questions about how this started.

186:20And again, if we had,

186:22like what is the United States government?

186:24Yeah, it's the executive branch, but there's also Congress.

186:27And Congress, you talk about Rand Paul,

186:29and as a former executive branch worker,

186:33when I was on the National Security Council,

186:35and I guess technically when I was at the State Department,

186:38all of this stuff, all of this process,

§20Transcript · 3:06:40–3:17:21

186:40it just seems like a pain in the ass.

186:42It's like these Fers, they're just attacking us.

186:46We tried to do this thing with,

186:48we had all the best intentions

186:49and now they're holding hearings

186:50and they're trying to box us in and whatever.

186:53But that's our process.

186:55And there's like a form of accountability as chaotic,

186:58as crazy as it is.

187:00And so it makes it really difficult.

187:03I mean, we have other problems of just chaos

187:05and everybody doing their own thing,

187:07but it makes it difficult to have

187:09the kind of systematic coverup.

187:11And again, all of that is predicated on my hypothesis,

187:15not fully proven, although I think likely

187:18that there is a lab incident origin of this pandemic.

187:22Well, I mean, we're having like several layers

187:25of conversation, but I think whether lab leak hypothesis

187:31is true or not, it does seem that the likelihood

187:36of a coverup, if it leaked from a lab is high.

187:41That's the more important conversation to be having.

187:45Well, you could argue a lot of things,

187:48but to me arguably, that's the more important conversation

187:51is about what is the likelihood of a coverup.

187:53100%, like in my mind, there is a legitimate debate

187:59about the origins of the pandemic.

188:01There are people who I respect,

188:04who I don't necessarily agree with,

188:06people like Stuart Neal, who's a virologist in the UK,

188:10who's been very open minded, engaged in productive debate

188:14about the origin and you know where I stand.

188:18There is and can be no debate about whether

188:23or not there has been a coverup.

188:25There has been a coverup.

188:26There is in my mind, no credible argument

188:29that there hasn't been a coverup.

188:31And I mean, we can just see it in the regulations,

188:35in the lack of access.

188:37There's an incredible woman named Zhang Zhan,

188:40who is a Chinese, we have to call her a citizen journalist

188:44because everything is controlled by the state.

188:46But in the early days of the pandemic,

188:47she went to Wuhan, started taking videos and posting them.

188:52She was imprisoned for picking quarrels,

188:54which is kind of a catchall.

188:57And now she's engaged in a hunger strike

189:00and she's near death.

189:02And so there's no question that there has been a coverup

189:06and there's no question in my mind

189:08that that coverup is responsible

189:10for a significant percentage of the total deaths

189:13due to COVID 19.

189:15In a pivot, can I talk to you about sex?

189:22Let's roll.

189:23Okay, so you're the author of a book, Hacking Darwin.

189:29So humans have used sex, allegedly, as I've read about,

189:36to mix genetic information to produce offspring

189:41and through that kind of process adapted their environment.

189:49Lex, you mentioned earlier about

189:51you're asking tough questions

189:53and people pushing you to ask tough questions.

189:56Is it okay if I just?

189:57So you said, have done this as I've read about.

190:01As I've read about on the internet, yeah.

190:03All I'm saying, as a person sitting with you,

190:06to people who would be open minded in experimenting

190:11of, as I've read about, to reality,

190:13what I would say is Lex Friedman is handsome, charming.

190:19He's really a great guy.

190:23I'm sorry to interrupt.

190:24Thank you, I appreciate that.

190:26So I was reading about this last night.

190:28I was gonna tweet it, but then I'm like,

190:30this is going to be misinterpreted.

190:32But this is why I like podcasts,

190:36because I can say stuff like this.

190:40It's kind of incredible to me that the average human male

190:45produces 500 billion plus sperm cells in their lifetime.

190:52Each one of those are genetically unique.

190:57They can produce unique humans.

190:59Each one of them, 500 billion,

191:01there's 100 billion people who's ever lived.

191:06Maybe 110, whatever, whatever the number is.

191:09So it's five times the number of people who ever lived

191:12is produced by each male of genetic information.

191:18So those are all possible trajectories of lives

191:20that could have lived.

191:22Those are all little people that could have been.

191:25And all the possible stories.

191:28All the Hitlers and Einsteins

191:31that could have been created.

191:32And all that, I mean, I don't know,

191:34this kind of, you're painting this possible future,

191:38and we get to see only one little string of that.

191:40I mean, I suppose the magic of that

191:43is also captured by the, in the space of physics,

191:47having multiple dimensions

191:49and the many worlds hypothesis of quantum mechanics,

191:53the interpretation that we're basically just,

191:57at every point, there's an infinite offspring

192:02of universes that are created.

192:04But I don't know, that's just like a magic

192:06of this game of genetics that we're playing.

192:11And the winning sperm is not the fastest.

192:16The winning sperm is basically the luckiest,

192:19has the right timing.

192:21So it's not, I also got into this whole,

192:24I started reading papers about like,

192:29is there something to be said

192:30about who wins the race, right, genetically?

192:34So it's fascinating, because there's studies

192:36in animals and so on to answer that question,

192:38because it's interesting, because I'm a winner, right?

192:41I won, I won a race.

192:43And so you want to know, what does that say about me

192:46in this fascinating genetic race against,

192:50I think, what is it, 200 million others, I think.

192:54So one pool of sperm cells is about something

193:01like 200 million, it could be, yes.

193:04But that, millions, I thought it was much lower than that.

193:08So like that, those are all brothers and sisters of mine,

193:13and I beat them all out, I won.

193:16And so it's interesting to know,

193:21there's a temptation to say I'm somehow better than them,

193:24right, and now that goes into the next stage

193:28of something we're deeply thinking about,

193:33which is if we have more control now

193:38over the winning genetic code that becomes offspring,

193:44if we have first not even control,

193:46just information and then control,

193:50what do you think that world looks like

193:53from a biological perspective

193:54and from an ethical perspective

193:56when we start getting more information and more control?

194:00Yeah, great question.

194:02So first, on the sperm, there can be up to

194:05about 1.2 billion sperm cells in a male ejaculation.

194:10So as I mentioned in Hacking Darwin,

194:13male sperm, it's kind of a dime a dozen

194:15with all the guys in all the world

194:18just doing whatever they do with it.

194:20And it's an open question how competitive,

194:25I mean, there is an element of luck

194:27and there is an element of competition,

194:31and it's an open question how much that competition

194:36impacts the outcome or whether it's just luck,

194:39but my guess is there's some combination

194:42of fitness and luck.

194:44But you're absolutely right that all of those other

194:48sperm cells in the ejaculation,

194:51if that's how the union of the sperm and egg is happening,

194:55all of them represent a different future.

194:59And there's a wonderful book called Invisible Cities

195:03by Italo Calvino, and he even talks about a city

195:08as something like this where everybody,

195:10you have your life,

195:12but then you have all these alternate lives

195:14and every time you make any decision,

195:16you're kind of, and so, but in this Invisible Cities,

195:19there's a little string that goes toward that alternate life

195:23and then the city becomes this weaving

195:25of all the strings of people's real lives

195:28and the alternate lives that they could have taken

195:31had they made any other different steps.

195:34So that part, it's like a deep philosophical question.

195:37It's not just for us, it's for all of,

195:39I mean, it's baked into evolutionary biology.

195:43It's just what are the different strategies

195:45for different species to achieve fitness?

195:48And there's some of the different corals or other fish

195:52where they just kind of release the eggs into the water

195:55and there's all different kinds of ways.

195:58And then you're right in my book, Hacking Darwin,

196:03and it's the full title is Hacking Darwin,

196:04Genetic Engineering and the Future of Humanity.

196:08I kind of go deep into exploring

196:12the big picture implications of the future

196:15of human reproduction.

196:17We are already participating

196:20in a revolutionary transformation,

196:23not just because of the diagnostics that we have,

196:26things like ultrasound, but because now

196:29an increasing number of us are being born

196:31through in vitro fertilization,

196:33which means the eggs are extracted from the mother,

196:36they're fertilized by the father's sperm in vitro in a lab,

196:41and then reimplanted in the mother.

196:45On top of that, there's a somewhat newer,

196:48but still now older technology

196:52called preimplantation genetic testing.

196:55And so as everyone knows from high school biology,

196:58you have the fertilized egg,

197:01and then it goes one cell to two cells

197:03to four to eight and whatever.

197:05And after around five days in this PGT process,

197:09a few cells are extracted.

197:12So let's say you have 10 fertilized eggs,

197:15early stage embryos, a few cells are extracted from each,

197:18and those cells, if they would,

§21Transcript · 3:17:21–3:26:52

197:21the ones that are extracted

197:22would end up becoming the placenta.

197:25But every one of our cells has, other than a few,

197:28has our full genome.

197:30And so then you sequence those cells

197:33and with preimplantation genetic testing now,

197:36what you can do is you can screen out deadly single gel,

197:41a single gene mutation disorders,

197:44things that could be deadly or life ruining.

197:47And so people use it to determine

197:49which of those 10 early stage embryos

197:53to implant in a mother.

197:55As we shift towards a much greater understanding

197:59of genetics, and that is part of our,

198:01just the broader genetics revolution,

198:04but within that, in our transition from personalized

198:07to precision healthcare, more and more of us

198:10are going to have our whole genome sequenced

198:12because it's gonna be the foundation

198:13of getting personalized healthcare.

198:16We're going to have already millions, but very soon,

198:19billions of people who've had their whole genome sequenced.

198:22And then we'll have big databases

198:24of people's genetic genotypic information

198:27and life or phenotypic information.

198:30And using, coming into your area,

198:32our tools of machine learning and data analytics,

198:35we're going to be able to increasingly understand

198:38patterns of genetic expression, even though we're all.

198:41So predict how the genetic information will get expressed.

198:44Correct. Yeah.

198:45Never perfectly perhaps, but more and more,

198:48always more and more.

198:50And so with that information, we aren't going to just be,

198:54even now, we aren't going to just be selecting based on

198:59which of these 10 early stage embryos

199:02is carrying a deadly genetic disorder,

199:04but we can, we'll be able to know everything

199:06that can be partly or entirely predicted by genetics.

199:12And there's a lot of our humanity

199:14that fits into that category.

199:17And certainly simple traits like height and eye color

199:22and things like that.

199:23I mean, height is not at all simple,

199:25but it's, if you have good nutrition,

199:28it's entirely or mostly genetic.

199:31But even personality traits and personality styles,

199:34there are a lot of things that we see just as the experience,

199:37the beauty of life that are partly have a genetic foundation.

199:42And so whatever part of these traits are definable

199:47and influenced by genetics,

199:49we're going to have greater and greater predictability

199:53within a range.

199:54And so selecting those embryos will be informed

199:59by that kind of knowledge.

200:02And that's why in Hacking Darwin,

200:04I talk about embryo selection as being a key driver

200:09of the future of human evolution.

200:11But then on top of that, there is in 2012,

200:15Shinya Yamanaka, an amazing Japanese scientist

200:19won the Nobel Prize for developing a process

200:22for creating what are called induced pluripotent stem cells,

200:26IPS cells.

200:27And what IPS cells are is you can induce an adult cell

200:31to go back in evolutionary time and become a stem cell.

200:35And a stem cell is like when we're a fertilized egg,

200:39like our entire blueprint is in that one cell

200:42and that cell can be anything,

200:44but then it starts to, our cells start to specialize.

200:48And that's why we have skin cells and blood cells

200:50and all the different types of things.

200:51So with the Yamanaka process,

200:54we can induce an adult cell to become a stem cell.

200:59So the relevance to this story is what you can do.

201:02And it works now in animal models.

201:05And as far as I know, it hasn't yet been done in humans,

201:08but it works pretty well in animal models.

201:11You take any adult cell,

201:12but skin cells are probably the easiest.

201:15You induce this skin cell into a stem cell.

201:19And if you just take a little skin graft,

201:21it would have millions of cells.

201:23You induce those skin cells into stem cells.

201:26Then you induce those stem cells into egg precursor cells.

201:31Then you induce those egg precursor cells into eggs,

201:35egg cells.

201:37Then because we have this massive overabundance

201:41of male sperm, then you could fertilize,

201:45let's call it 10,000 of the mother's eggs.

201:49So you have 10,000 eggs, which are fertilized.

201:52Sounds like a party.

201:53Yeah.

201:54Then you have an automated process

201:58for what I mentioned before

202:00in preimplantation genetic testing,

202:02you grow them all for five days,

202:04you extract a few cells from each, you test them.

202:07And that's why I had a piece in the New York Times

202:09a couple of years ago,

202:09imagining what it would be like to go to a fertility clinic

202:12in the year 2050.

202:14And the choice is not.

202:15No humans involved.

202:16Yeah.

202:17Well, no, no, there are, but the choice is not,

202:19do you want a kid who does or doesn't have,

202:22let's call it Tay Sachs.

202:25It's a whole range of possibilities,

202:28including very intimate traits

202:33like height, IQ, personality style.

202:35It doesn't mean you can predict everything,

202:37but it means there will be increasing predictability.

202:41So if you're choosing from 10,000 eggs,

202:45fertilized eggs, early stage embryos,

202:47that's a lot of choice.

202:49And on top of that,

202:52then we have the new technology of human genome editing.

202:57Many people have heard of CRISPR,

203:00but what I say is if you think of human genome editing

203:02as a pie, sorry, human genome engineering as a pie,

203:07genome editing is a slice

203:08and CRISPR is just a sliver of that slice.

203:11It's just one of our tools for genome editing

203:13and things are getting better and better.

203:16Then you can go in and change.

203:20Let's say, I mean, again, it starts simple.

203:23A small number of genes,

203:24let's say you've selected from among the one of 10

203:27or the one of 10,000,

203:29but there are a number of changes

203:31that you would like to make to achieve some kind of outcome.

203:33And biology is incredibly complex

203:36and it's not that one gene does one thing.

203:38One gene does probably a lot of things simultaneously,

203:42which is why the decision about changing one gene

203:45if it's causing deathly harm is easier

203:48than when we think about the complexity of biology.

203:51But then the machine learning

203:52gets better and better at predicting

203:54the full complexity of biology.

203:55So as one gets better,

203:58then you're editing your ability to reliably edit

204:03such that the conclusions are predictable,

204:04it gets better and better.

204:05So those two are coupled together.

204:07You got it, that's exactly it.

204:08And then, so that's why, and people would say,

204:11well, that, I mean, I wrote about that

204:12in my two science fiction novels,

204:15Genesis Code and Eternal Sonata years ago,

204:18and especially with Genesis Code, I wrote about that.

204:20And as a sci fi,

204:22and I had actually testified before Congress,

204:25but now 15 years ago saying,

204:27here's what the future looks like.

204:30But even I, and in my first edition of Hacking Darwin,

204:35when it was already in production,

204:38and then in November 2018,

204:41this scientist, Hojong Kui, announced in Hong Kong

204:47that the world's first two, and later three,

204:50CRISPR babies had been born,

204:51which he had genetically altered,

204:53and misguided, in my view, and dangerous view,

204:57dangerous goal of making it so they would have

205:02increased resistance to HIV.

205:07And so I called my publisher,

205:09and I said, I've got good news and bad news.

205:11I'll start with the bad news,

205:13is that the world's first CRISPR babies have been born,

205:17and so we need to pull my book out of production,

205:21because you can't have a book on the future

205:22of human genetic engineering,

205:24and have it not mention the first CRISPR babies

205:27that had been born.

205:28But the good news is, in the book,

205:31I had predicted that it's going to happen,

205:34and it's going to happen in China, and here's why.

205:37And all we need to do is add a few more sentences,

205:42and that was the hardback,

205:43and then I updated it more in the paperback,

205:45saying, and it happened, and it was announced on this day.

205:48Yeah.

205:50Well, then let's fast forward.

205:52Given your predictions are slowly becoming reality,

205:59let's talk about some philosophy,

206:01and ethics, I suppose.

206:03So I can, I'm not being too self deprecating here,

206:07and saying if my parents had the choice,

206:14I would be probably less likely to come out the winner.

206:18We're all weird, and I'm certainly a very distinctly

206:23weird specimen of the human species.

206:26I can give the full long list of flaws,

206:29and we can be very poetic of saying those are features,

206:33and so on, but they're not.

206:37If you look at the menu.

206:40Again, for these women who are listening,

206:42apropos of your thing,

206:43they're all kind of charming individualities.

206:47Yes, that's beautiful, that's one, yes, thank you.

206:50But anyway, but on the full sort of individual,

§22Transcript · 3:26:52–3:37:38

206:52let's say IQ alone, right?

206:55That what do we do about a world

207:02where IQ could be selected on a menu

207:09when you're having children?

207:13What concerns you about that world?

207:15What excites you about that world?

207:17Are there certain metrics that excite you more than others?

207:25IQ has been a source of,

207:31I don't know, I'm not sure IQ as a measure,

207:36flawed as it is, has been used to celebrate

207:40the successes of the human species

207:43nearly as much as has been used to divide people,

207:47to say negative things about people,

207:51to make negative claims about people.

207:54And in that same way, it seems like

207:57when there's a selection, a genetic selection based on IQ,

208:01you can start now having classes of citizenry,

208:05like further divide, you know, the rich get richer.

208:09You know, it'll be very rich people

208:12that'll be able to do kind of fine selection of IQ

208:16and they will start forming these classes

208:22of super intelligent people.

208:23And those super intelligent people in their minds

208:26would of course be the right people

208:27to be making global authoritarian decisions

208:30about everybody else, all the usual aspects of human nature,

208:33but now magnified with the new tools of technology.

208:38Anyway, all that to say is what's exciting to you?

208:42What's concerning to you?

208:44It's a great question and just stepping into the IQ,

208:48we'll call it a quagmire for now,

208:51it raises a lot of big issues which are complicated.

208:57Maybe you've listened to Sam Harris's interview

209:02with Charles Murray and then that spawned

209:05kind of a whole industry of debate.

209:10So first, just the background of IQ

209:13and it's from the early 20th century

209:16and there was the idea that we can measure

209:19people's general intelligence

209:21and there are so many different kinds of intelligence.

209:23This was measuring a specific thing.

209:25So my feeling is that IQ is not a perfect measure

209:30of intelligence, but it's a perfect measure of IQ.

209:33Like it's measuring what it's measuring,

209:35but that thing correlates to a lot of things

209:40which are rewarded in our society.

209:43So every study of IQ has shown that people

209:47with higher IQs, they make more money,

209:51they live longer, they have more stable relationships.

209:53I mean, that could be something in the testing,

209:56but as Sam Harris has talked about a lot,

210:00you could line up all of these kind of IQ

210:03and IQ like tests correlate with each other.

210:07So the people who score high on one, score high on all

210:10of them and people think that IQ tests are like a thing

210:15like the Earl of Dorchester is coming for dinner.

210:18Does he have two forks or three forks

210:21or something like that?

210:22It's not that a lot of them are things

210:24that I think a lot of us would recognize are relevant.

210:27Just like how much stuff can you memorize?

210:30If you see some shapes, how can you position them

210:33and things like that.

210:36And so IQ, I mean, it really hit its stride

210:38and certainly in the second world war

210:40when our governments were processing a lot of people

210:43and trying to figure out who to put in what jobs.

210:47So that's the starting point.

210:48Let me start first with the negatives.

210:53That our societies, when we talk about diversity

210:56in Darwinian terms, it's not like diversity

211:00is from Darwinian terms.

211:01Oh, wouldn't it be nice if we have some moths

211:05of different colors because it'll be really fun

211:08to have different colored moths.

211:10Diversity is the sole survival strategy of our species

211:14and of every species.

211:15And it's impossible to predict what diversity

211:21is going to be rewarded.

211:22And I've said this before, if you went down

211:25and you spoke T. rex and you spoke to the dinosaurs

211:29and said, hey, you can select your kids,

211:31what criteria do you want?

211:33And they say, oh, yeah, sharp teeth, cruel fangs,

211:37roar, whatever it is that makes you a great T. rex.

211:42But the answer from an evolutionary perspective,

211:46from an earth perspective was, oh, it's much better

211:48to be like a cockroach or an alligator

211:50or some little nothing or a little shrew

211:54because the dinosaurs are gonna get wiped out

211:57when the asteroid hits.

211:58And so there's no better or worse in evolution.

212:01There's just better or worse suited for a given environment.

212:05And when that environment changes,

212:07the best suited person from the old system

212:11could be the worst suited person for the new one.

212:14So if we start selecting for the things

212:17that we value the most, including things like IQ,

212:21but even disease resistance, I mean, this is well known,

212:26but people who are recessive carrier of sickle cell disease

212:32have increased resistance to malaria,

212:34which is the biggest reason why that trait

212:37hasn't just disappeared given how deadly

212:41sickle cell disease is.

212:43Biology is incredibly complex.

212:46We understand such a tiny percentage of it

212:49that we need to have, in your words,

212:50just a level of humility.

212:53There are huge equity issues as you've articulated.

212:56Let's just say that it is the case that in our society,

212:59IQ and IQ like traits are highly rewarded.

213:05There is an equity issue, but it works in both ways.

213:08Because my guess is, let's just say that we had a society

213:11where we were doing genome sequencing

213:13of everybody who was born.

213:15And we had some predictive model to predict IQ.

213:18And we had decided as a society that IQ

213:22was going to be what we were going to select for.

213:24We were gonna put the highest IQ people

213:26in these different roles.

213:28I guarantee you the people in those roles

213:31would not be the people who are legacy admissions to Harvard.

213:36They would very likely be people who are born in slums,

213:40people who are born with no opportunity or in refugee camps

213:44who are just wasting away because we've thrown them away.

213:49And so it's an easy, like it's the idea of just being able

213:54to look under the hood of our humanity

213:57is really scary for everybody.

214:01And it should be.

214:02I mean, I'm also an Ashkenazi Jew.

214:05My father was born in Austria.

214:07My father and grandparents came here as refugees.

214:10After the war, most of that side of the family was killed.

214:14So I get what it means to be on the other,

214:19I mean, you said you're reading Mein Kampf,

214:19on the other side of the story when someone said,

214:22well, here's what's good and you're not good.

214:25And therefore you're, so I totally get that.

214:29Having said that, I do believe that we're moving toward

214:35a new way of procreating.

214:37And we're going to have to decide what are the values

214:40that we would like to realize through that process?

214:45Is it randomness, which is what we currently have now,

214:48which is not totally random

214:49because we have a sort of mating through colleges

214:52and other things.

214:54But if it's.

214:54Wait, mating through what?

214:55Colleges?

214:56Sort of like if you go, if you go to Harvard or whatever,

215:01and your wife also goes to Harvard, it's like, it's.

215:05So it's location based mating.

215:07Well, it's not location, it's selection.

215:09It's like there are selections that are made

215:11about who gets to a certain place.

215:14And when like, it's like Harvard admissions is a filter.

215:17So we're going to have to decide what are the values

215:19that we want to realize through this process

215:21because diversity has, it's just baked into our biology.

215:24We're the first species ever that has the opportunity

215:28to make choices about things that were otherwise baked

215:32into our biology.

215:33And there's a real danger that if we make bad choices,

215:37even with good intentions, it could even drive us

215:40toward extinction and certainly undermine our humanity.

215:45And that's why I always say, and like I said,

215:47I'm deeply involved with WHO and other things,

215:50that these aren't conversations about science.

215:53They're conversations.

215:54Science brings us to the conversation,

215:56but the conversation is about values and ethics.

215:58As you described, that world is wide open.

216:00It's not even a subtly different world.

216:04That world is fundamentally different

216:06from anything we understand about life on Earth

216:09because natural selection, this random process,

216:15is so fundamental how we think about life.

216:18Being able to program, I mean, it has a chance to,

216:23I mean, it'll probably make my question

216:25about the ethical concerns around IQ based selection

216:29just meaningless because it'll change the nature of identity.

216:37It's possible it will dissolve identity

216:41because we take so much pride in all the different

216:45characteristics that make us who we are.

216:48Whenever you have some control over those characteristics,

216:51those characteristics start losing meaning.

216:55And what may start gaining meaning is the ideas

216:58inside our heads, for example,

217:00versus like the details of like,

217:05is it a Commodore 64, is it a PC, is it a Mac?

217:10It's gonna be less important than the software

217:12that runs on it.

217:14So we can more and more be operating in the digital space

217:17and the identity could be something

217:18that borrows multiple bodies.

217:20Like the legacy of our ideas may become more important

217:24than the details of our physical embodiment.

217:28Like it, I mean, I'm saying perhaps

217:30ridiculous sounding things, but the point is

217:33it will bring up so many new ethical concerns

§23Transcript · 3:37:38–3:46:14

217:38that our narrow minded thinking about

217:40the current ethical concerns would not apply.

217:43So it's, but it's important to think about

217:46all this kind of stuff, like actively.

217:49What are the right conversations to be having now?

217:51Because it feels like it's an ongoing conversation

217:56that then continually evolves, like with NIH involved.

217:59Like do you do experiments with animals?

218:03Do you build these brain organoids?

218:06Do you, like through that process you described

218:08with the stem cells, like do you experiment

218:10with a bunch of organisms to see how genetic material,

218:16what form that actually takes,

218:18how to minimize the chance of cancer

218:19and all those kinds of things.

218:20What are the negative consequences of that?

218:22What are the positive consequences?

218:24Yeah, it's a fascinating world.

218:26It's a really fascinating world.

218:28Yeah, and then, but those conversations

218:29are just so essential.

218:32Like we have to be talking about ethics.

218:34And then that raises the question of who is the we?

218:37And coming back to your conversation

218:39about science communication,

218:41maybe there was a time earlier

218:44when these conversations needed to be,

218:46were held among a small number of experts

218:49who made decisions on behalf of everybody else.

218:53But what we're talking about here

218:54is really the future of our species.

218:57And I think that conversation is too important

219:01to be left just to experts and government officials.

219:04So I mentioned that I'm a member,

219:06we just ended our work after two years

219:09of the World Health Organization Expert Advisory Committee

219:11on Human Genome Editing.

219:13And my big push in that process

219:16was to have education, engagement and empowerment

219:21of the broad public to bring,

219:23not just bring people into the conversation

219:25with the tools to be able to engage,

219:29but also into the decision making process.

219:31And that's, it's a real shift.

219:33And there are countries that are doing it

219:35better than others.

219:37I mean, Denmark is obviously a much smaller country

219:39than the United States,

219:40but they have a really well developed infrastructure

219:44for public engagement

219:46around really complicated scientific issues.

219:49And I just think that we have to,

219:50like it's great that we have Twitter

219:53and all these other things,

219:55but we need structured conversations

219:58where we can really bring people together

220:00and listen to each other,

220:02which feels like it's harder than ever.

220:06But even now in this process

220:08where all these people are shouting at each other,

220:11at least there are a bunch of people

220:12who are in the conversation.

220:14So it's, we have a foundation,

220:16but we just really need to do more work.

220:20And again, and again, and again,

220:21it's about ethics and values

220:24because we're at an age,

220:27and this has become a cliche

220:28of exponential technological change.

220:31And so the rate of change is faster going forward

220:35than it has been in the past.

220:36So in our minds, we underappreciate

220:39how quickly things are changing and will change.

220:43And if we're not careful,

220:44if we don't know who we are and what our values are,

220:48we're going to get lost.

220:49And we don't have to know technology.

220:52We have to know who we are.

220:53I mean, our values are hard won over thousands of years.

220:58No matter how new the technology is,

221:01we shouldn't and can't jettison our values

221:04because that is our primary navigational tool.

221:08Absurd question.

221:09Because we were saying that sexual reproduction

221:15is not the best way to define the offspring.

221:17You think there'll be a day when humans stop having sex?

221:21I don't think we'll stop having sex

221:23because it's so enjoyable,

221:26but we may significantly stop having sex for reproduction.

221:30Even today, most human sex is not for making babies.

221:35It's for other things,

221:36whether it's pleasure or love or pair bonding or whatever.

221:40Intimacy.

221:41Intimacy.

221:42I mean, some people do it for intimacy.

221:44Some people do it for pleasure with strangers.

221:46I feel like the people that do it for pleasure,

221:48I feel like there will be better ways

221:50to achieve that same chemical pleasure, right?

221:54You know, there's just so many different kinds of people.

221:57I just saw this on television,

222:00but there are people who put on those big bunny outfits

222:02and go and have sex with other people.

222:04I mean, there's just like an unlimited number

222:06of different kinds of people.

222:07I think they're called,

222:09so I remember hearing about this,

222:10I think Dan Savage is a podcast.

222:14I think they're called Furries.

222:16Furries.

222:17Furries.

222:18Furry parties.

222:19Yeah, exactly.

222:20So they're just...

222:20I love people.

222:21Yeah, well, that's like the thing.

222:24It's like, whenever you hear these words,

222:25it's like, humans.

222:27Yeah, yeah.

222:28What will they think of next?

222:30So, but I do think that,

222:31and I write about this in Hacking Darwin,

222:33that as people come to believe that having,

222:39that making children through the application of science

222:43is safer and more beneficial

222:46than having children through sex,

222:48we'll start to see a shift over time

222:52toward reproduction through science.

222:54We'll still have sex for all the same great reasons

222:58that we do it now,

223:00it's just reproduction less and less through the act of sex.

223:04Man, it's such a fascinating future.

223:08Because as somebody, I value flaws.

223:11I think it's the good will hunting,

223:17that's the good stuff.

223:18The flaws, the weird quirks of humans,

223:21that's what makes us who we are, the weird.

223:25The weird is the beautiful.

223:26And I, there's a fear of optimization that I...

223:33You should have it.

223:33I mean, it's very healthy.

223:35And I think that's, I was saying before,

223:36that's the danger of all of this selection

223:39is that we make selections just based on social norms

223:44that are so deeply internal

223:47that they feel like they're eternal truths.

223:51And so we talked about selecting for IQ.

223:54What about selecting for a kind heart?

223:56Like there are lots of them.

223:57You talked about Hitler and Mein Kampf.

223:59Hitler had certainly had a high IQ,

224:03I guess is higher than average IQ.

224:06If we just select,

224:07I mean, that's why I was saying before,

224:11diversity is baked into our biology.

224:13But the key lesson, and I've said this many times before,

224:16the key lesson of this moment in our history

224:18is that after nearly 4 billion years of evolution,

224:22our one species suddenly has the unique

224:26and increasing ability to read, write,

224:28and hack the code of life.

224:30And so as we apply these godlike powers

224:34that we've now assumed for ourselves,

224:37we better be pretty careful

224:39because it's so easy to make mistakes,

224:44particularly mistakes that are guided

224:47by our best intentions.

224:49To jump briefly back onto lab leak,

224:52and I swear there's a reason for that,

224:55what did you think about the Jon Stewart,

224:59this moment, I forget when it was, maybe a few months ago,

225:02in the summer, I think, of 2021,

225:05where he went on Colbert Report,

225:07or not the Colbert Report, sorry,

225:09the Stephen Colbert's, whatever his show is.

225:13But again, Jon Stewart reminded us

225:15how valuable his wit and brilliance

225:18within the humor was for our culture.

225:22And so he did this whole bit

225:24that highlighted the common sense nature

225:27about what was the metaphor he used

225:30about the Hershey factory in Pennsylvania.

225:33So what'd you think about that whole bit?

225:34I loved it.

225:36And so not to be overly self referential,

225:40but it's hard not to be overly self referential

225:43when you're doing a, however long we are,

225:45five hour interview about yourself,

225:47which it reminds me of when you had Bret Weinstein on,

225:50he said, I have no ego,

225:52but these 57 people have screwed me over,

225:55and I deserve credit.

225:56It's hard.

225:57So I am a person, I will confess, it's enjoyable.

226:02Some people feel different.

226:03I kind of like talking about all this stuff

226:06and talking, period.

226:08So for me, in the earliest,

226:10I remember those early days of when the pandemic started,

226:13I was just sitting down,

§24Transcript · 3:46:14–3:56:12

226:14it was late January, early February, 2020,

226:17and I just was laying out all of the evidence

226:20just that I could collect,

226:22trying to say, make sense of where does this come from?

226:26And it was just logic.

226:28I mean, it was all of the things that Jon Stewart said,

226:32which in some overly wordy form

226:36were all at that time on my website.

226:38Like, what are the odds of having this outbreak

226:42of a bat coronavirus more than a thousand miles away

226:45from where these bats have their natural habitat,

226:48where they have this largest collection

226:52of these bat coronaviruses in the world,

226:54and they're doing all these very aggressive

226:58research projects to make them more aggressive.

227:01And then you have the outbreak of a virus

227:04that's primed for human to human transmission.

227:09It was just logic was my first step.

227:12And I kept gathering the information.

227:17But Jon Stewart distilled that

227:19in a way that just everybody got.

227:23And I think that, like, I loved it.

227:26And I just think that there's a way of reaching people.

227:28It's the reason why I write science fiction

227:31in addition to thinking and writing about the science

227:34is that we kind of have to reach people where they are.

227:37And I just thought it was just,

227:40there was a lot of depth, I thought,

227:42and maybe that's too self serving,

227:46but like in the analysis,

227:48but he captured that into those things about,

227:54it's like the, whatever, the outbreak of chewy goodness

227:58near the Hershey factory.

228:00I wonder where that came from.

228:01Yeah, there's the humor, there's metaphor.

228:05Also the, like, sticking with the joke

228:07when the audience is,

228:12the audience is Stephen Colbert.

228:13He was, like, resisting it.

228:16He was very uncomfortable with it.

228:17Maybe that was part of the bit, I'm not sure,

228:19but it didn't look like it.

228:21So Stephen in that moment kind of represented

228:24the discomfort of the scientific community, I think.

228:26It's kind of interesting, that whole dynamic.

228:28And I think that was a pivotal moment.

228:32That just, like, highlights the value of comedy,

228:35the value of, like, when Joe Rogan says,

228:39I'm just a comedian.

228:42I mean, that's such a funny thing to say.

228:46It's like saying I'm just a podcaster

228:48or I'm just a writer, I'm just a, you know.

228:51That ability in so few words

228:55to express what everybody else is thinking,

229:00it's so refreshing.

229:02And I wish the scientific communicators would do that too.

229:06A little humor, a little humor.

229:08I mean, that's what I love Elon Musk very much.

229:10So, like, the way he communicates is, like,

229:13it's so refreshing for a CEO of a major company,

229:18several major companies, to just have a sense of humor

229:22and say ridiculous shit every once in a while.

229:24That's so, there's something to that.

229:26Like, it shakes up the whole conversation

229:29to where it gives you freedom to, like, think publicly.

229:33If you're always trying to say the proper thing,

229:36you lose the freedom to think, to reason out,

229:40to be authentic and genuine.

229:42When you allow yourself the freedom

229:44to regularly say stupid shit,

229:48have fun, make fun of yourself,

229:51I think you give yourself freedom

229:53to really be a great scientist.

229:55Honestly, I think scientists have a lot to learn

229:58from comedians.

230:00Well, for sure.

230:00I think we all do about just distilling and communicating

230:05in ways that people can hear.

230:07Like, a lot of us say things and people just can't hear them

230:10either because of the way we're saying them

230:12or where they are, but.

230:14And like I said before, I'm a big fan of Joe Rogan.

230:19I've been on his show twice.

230:20And when Francis Collins was in his conversation with you,

230:25he said, which I think makes sense,

230:27is that when somebody has that kind of platform

230:31and people rightly or wrongly who follow them

230:34and look to them for guidance,

230:36I do think that there is some responsibility

230:40for people in those roles to make whatever judgment

230:45that they make and to share that.

230:47And as I mentioned to you when we were off mic,

230:50Sanjay Gupta is a very close friend of mine.

230:53We've been friends for many years

230:54and I fully supported Sanjay's instinct

230:58to go on the Joe Rogan show.

231:02I thought it was great.

231:05At the end of that whole conversation, Joe said,

231:09well, I'm just a comedian, what do I know?

231:12And I just felt that, yes, Joe Rogan is a comedian.

231:16I wouldn't say just a comedian among other things.

231:20But I also felt that he had a responsibility

231:23for just saying whatever he believed,

231:25even if he believed or believes as I think is the case

231:30that ivermectin should be studied more,

231:32which I certainly agree.

231:34And that healthy people shouldn't get vaccinated,

231:40healthy young people, which I don't agree.

231:42I just felt at the end of that conversation to say,

231:44well, I'm just a comedian, what do I know?

231:47I feel like it didn't fully integrate the power

231:51that a person like Joe Rogan has to set the agenda.

231:55So I think the reason he says I'm just a comedian

231:58is the same reason I say I'm an idiot,

232:00which I truly believe.

232:02I can explain exactly what I mean by that,

232:03but it's more for him, or in this case for me,

232:09to just keep yourself humble.

232:11Because I think it's a slippery slope

232:14when you think you have a responsibility

232:16to then think you actually have an authority,

232:21because a lot of people listen to you,

232:22you think you have an authority

232:24to actually speak to those people

232:26and you have enough authority

232:27to know what the hell you're talking about.

232:29And I think there's just the humility

232:31to just kind of make it fun of yourself

232:34that's extremely valuable.

232:35And saying I'm just a comedian I think is a reminder

232:40to himself that he's often full of shit, so are all of us.

232:48And so that's a really powerful way for himself

232:51to keep himself humble.

232:53I mean, I think that's really useful

232:55in some kind of way for people in general

232:57to make fun of themselves a little bit,

233:00in whatever way that means.

233:02And saying I'm just a comedian is just one way to do that.

233:04Now that coupled that with the responsibility

233:07of doing the research and really having an open mind

233:10and all those kinds of stuff,

233:12I think that's something Joe does really well

233:15on a lot of topics, but he can't do that on everything.

233:18And so it's up to people to decide

233:22how well he does it on certain topics and not others.

233:26But how do you think Sanjay did in that conversation?

233:29So I know I'm gonna get myself into trouble here

233:31because Sanjay is a very close friend.

233:35Joe, my personal interaction with him

233:38has been our two interviews,

233:39but it's like my interview with now,

233:41sit down with somebody for four hours,

233:43it's a lot and great and then private communication.

233:48So I am personally more sympathetic to the arguments

233:53that Sanjay was making or trying to make.

233:58I believe that the threat of the virus

234:01is greater than the threat of the vaccine.

234:03That doesn't mean that we can guarantee 100% safety

234:08for the vaccine,

234:09but these are really well tolerated vaccines.

234:13And we know for all the reasons we've been talking about

234:15that this is a really scary virus

234:18and particularly the mRNA vaccines,

234:20what they're basically doing is getting your body

234:23to replicate a tiny little piece of the virus,

234:25the spike protein and then your body responds to that.

234:29And so that's a much less of an insult to your body

234:34than being infected by the virus.

234:37So I'm more sympathetic to the people who say,

234:41well, everybody should get vaccinated,

234:44but people who've already been infected,

234:47we should study whether they need to be vaccinated or not.

234:52Having said all of that, I felt that

234:57that Joe Rogan won the debate.

234:59I mean, it was, and the reason that I felt

235:02that he won the debate was they were kind of,

235:05they had two different categories of arguments.

235:08So Sanjay, what he was trying to do,

235:11which I totally respect was saying,

235:13there's so much animosity between the,

235:15on these different sides, let's lower the temperature.

235:17Let's model that we can have a respectful dialogue

235:22with each other where we can actually listen.

235:24And Sanjay, again, I've known him for many years.

235:27He's a very empathic, humble,

235:30just an all around wonderful human being,

235:33and I really love him.

235:35And so he was making cases that were based on

235:38kind of averages, studies and things like that.

235:41And Joe was saying, well, I know a guy whose sister's cousin

235:45had this experience.

235:48And I'm sure that it's all true in the sense

235:51that we have millions of people who are getting vaccinated

235:54and different things.

235:56And what Sanjay should have said was,

235:59I know that's anecdote.

236:01Here's another anecdote of like when Francis Collins

236:04was with you and he talked about the world wrestling guy

236:07who was like 6.6 and a big muscly guy,

236:10and then he got COVID and he was anti vaccine,

§25Transcript · 3:56:12–4:05:22

236:12and then he got COVID and almost died.

236:14And he said, I'm gonna.

236:15By the way, I don't know if you know this part.

236:17No.

236:18Oh, this is funny.

236:19Joe's gonna listen to this.

236:20He's gonna be laughing.

236:21Does Joe listen like to the four hours of this

236:24in addition to the three hours of his interviews every day?

236:28No, not every day, but he listens to a lot of these.

236:30I love it.

236:31And we talk about it.

236:32I love it.

236:33We argue about it.

236:34Hi, Joe.

236:34Hey, Joe.

236:35We love you, Joe.

236:37So that particular case,

236:40I don't know why Francis said what he said there,

236:43but that's not accurate.

236:45Oh, really?

236:45So the wrestler never, he didn't almost die.

236:50He was no big deal at all for him.

236:53And he said that to him.

236:54I think, I'm not sure.

236:56I think something got mixed up in Francis's memory.

237:00There was another case he must've been like,

237:02cause I don't imagine he would bring that case up

237:05and just like make it up, you know, cause like why?

237:09But he, that was not at all,

237:11like that was a pretty public case.

237:13He had an interview with him, that wrestler,

237:16he was just fine.

237:17So that anecdotal case, I mean,

237:19Francis should not have done that.

237:21So if I have any, so I have a bunch of criticism

237:24of how that went.

237:26People who criticize that interview,

237:28I feel like don't give enough respect

237:32to the full range of things

237:33that Francis Collins has done in his career.

237:35He's an incredible scientist.

237:37And I also think a really good human being.

237:40But yes, that conversation was flawed in many ways.

237:44And one of them was why,

237:47when you're trying to present some kind of critical,

237:53like criticize Joe Rogan,

237:56why bring up anecdotal evidence at all?

237:58And if you do bring up anecdotal evidence,

238:02which is not scientific, if you're a scientist,

238:04you should not be using anecdotal evidence.

238:06If you do bring it up,

238:07why bring up one that's first not true

238:12and you know it's not true?

238:15So I know, pretend, so you don't know it's not true.

238:18So yes, that would find another case where, exactly.

238:23So the basic thing coming back

238:24to Sanjay and Joe's conversation

238:28was that Sanjay was trying to use statistical evidence

238:31and Joe was using anecdotal evidence.

238:33And so I think that for Sanjay,

238:36and there are all kinds of things where there are debates

238:39where often the person who's better at debating

238:42wins the debate regardless of the topic.

238:46So I think what Sanjay could have done,

238:49and Sanjay is such a smart guy,

238:53is to say, well, that's an anecdote,

238:55here's another anecdote.

238:57And there are lots of different anecdotes.

239:00And there certainly are people who have taken the vaccine

239:03and have had problems that could reasonably be traced

239:07to the vaccines.

239:08And there certainly are lots of people, I would argue,

239:11more people who've not had the vaccine,

239:14but who've gotten COVID and have either died

239:16or our hospitals are now full of people

239:19who weren't vaccinated.

239:20And in many ways, I mean, our emergency rooms

239:23are full of unvaccinated people here in the United States.

239:26So I think what Sanjay could have done,

239:28but there was a conflict between wanting to kind of

239:32win the debate and wanting to take the temperature down.

239:36And what he could have done is to say,

239:39well, here's an anecdote, I have a counter anecdote

239:42and we can go on all day,

239:43but here's what the statistics show.

239:46And I think that was the thing.

239:48So I think it's a healthy conversation.

239:50We can't, I mean, there are a lot of people

239:52who are afraid of the vaccine.

239:55There are a lot of people who don't trust

239:56the scientific establishment

239:58and lots of them have good reason.

240:00I mean, it's not just people think of like Trump Republicans.

240:04There are lots of people in the African American community

240:08who've had a historical terrible experience

240:11with the Tuskegee and all sorts of things.

240:14So they don't trust the messages

240:16that were being delivered.

240:18I live in New York City and we had a piece

240:21in the New York Times where in the earliest days

240:23of the vaccines, there was this big movement,

240:25let's make sure that the poorest people in the city

240:28have first access to the vaccines

240:31because they're the ones, they have higher density

240:35in their homes, they're relying on public transport.

240:37So there was this whole liberal effort.

240:39And then in the black community in New York,

240:42according to the New York Times,

240:43there was very low acceptance of the vaccines

240:46and they interviewed people in that article.

240:48And they said, well, if the white people want us

240:51to have it first, there must be something wrong with it.

240:54They must be doing something.

240:56And so we have to listen to each other.

240:59Like I would never, I have a disrespect for everybody.

241:04And if somebody is cautious about the vaccine

241:07for themselves or for their children,

241:10we have to listen to them.

241:12At the same time, public health

241:15is about creating public health.

241:19And there's no doubt, I think Joe was absolutely right

241:23that older people, obese people are at greater risk

241:28for being harmed or killed by COVID 19

241:32than young, healthy people.

241:34But by everybody getting vaccinated,

241:38we reduce the risk to everybody else.

241:41And so I feel like, like with everything,

241:43there's the individual benefit argument

241:46and then there's the community argument.

241:49And I absolutely think our community.

241:50Expressing that clearly that there's a difference between

241:53the individual health and freedoms

241:56and the community health and freedoms

241:59and steel manning each side of this.

242:01One of the problems that people don't do enough of

242:05is be able to, so how do you steel man an argument?

242:08You describe that argument in the best possible way.

242:12You have to first understand that argument.

242:14Let's go to the noncontroversial thing like Flat Earth.

242:17Like most people, most colleagues of mine at MIT

242:23don't even read about like the full argument

242:28that the Flat Earthers make.

242:31I feel it's disingenuous for people in the physics community

242:37to roll their eyes at Flat Earthers

242:39if they haven't read their arguments.

242:42You should feel bad that you didn't read their arguments.

242:46And like it's the rolling of the eyes that's a big problem.

242:50You haven't read it.

242:51Your intuition says that these are a bunch of crazy people.

242:55Okay, but you haven't earned the right to roll your eyes.

242:59You've earned your right to maybe not read it,

243:03but then don't have an opinion.

243:05Don't roll your eyes, don't do any of that dismissive stuff.

243:07And the same thing in the scientific community

243:11around COVID and so on, there's often this kind of saying,

243:14oh God, that's conspiracy theories, that's misinformation

243:17without actually looking into what they're saying.

243:20If you haven't looked into what they're saying,

243:22then don't talk about it.

243:23Like if you're a scientific leader and the communicator,

243:26you need to look into it.

243:27It's not that much effort.

243:28I totally agree.

243:29And I think that humility,

243:31it's a constant theme of your podcasts and I love that.

243:35And so after the conversation debate,

243:39whatever it was between Sanjay and Joe,

243:42I reached out on Twitter to someone I've never met

243:45in person, but I'm in touch privately

243:47to a guy named Daniel Griffin,

243:49who's a professor at Columbia Medical School

243:54and just so smart there.

243:56He gives regular updates on COVID 19

244:00on a thing called TWIV this week in virology.

244:03I'm a critic of TWIV for its coverage of origins.

244:09But on this issue, I'm just having regular updates.

244:12Daniel is great.

244:13And so I said to him,

244:15I said, why don't we have an honest process

244:20to get the people who are raising concerns

244:22about the vaccines in their own words

244:25to raise what are their concerns?

244:28And then let's do our best job of saying,

244:32well, here are these concerns.

244:34And then here is our evidence making a counterclaim

244:38and here are links to if you want to look at the studies

244:41upon which these claims are made, here they are.

244:45And Daniel, who's incredibly busy,

244:47I mean, he reads every, I mean, it seems every paper

244:51that comes out every week and it's unbelievable.

244:55But he sent me a link to the CDC Q&A page

245:00on the CDC website.

245:02And it wasn't that, it was people who were,

245:05I mean, it was written by people like me

245:07who were convinced in the benefit of these vaccines.

245:13So the questions were framed, they were kind of like,

245:16they weren't really the framing

245:19of the people with the concerns.

245:21They were framing of people

§26Transcript · 4:05:22–4:15:27

245:22who were just kind of imagining something else.

245:25I mean, you always talk about kind of humility

245:27and active listening.

245:29I know you don't mean, and it doesn't mean

245:31that we don't stand for something.

245:33Like I certainly am a strong proponent of vaccines

245:36and masks and all of those things.

245:39But if we don't hear other people,

245:42if we don't let them hear their voice in the conversation,

245:47if it's just saying, well, you may think this

245:49and here's why it's wrong, the argument may be right.

245:52It'll just never break through.

245:53By the way, my interpretation of Joe and Sanjay,

245:56I listened to that conversation without looking at Twitter

245:58or the internet and I thought that was a great conversation

246:01and I thought Sanjay actually really succeeded

246:04in bringing the temperature down.

246:05To me, the goal was bringing the temperature down.

246:08I didn't even think of it as a debate.

246:10I was like, oh, cool, this isn't gonna be some weird,

246:13it's like two friendly people talking.

246:15And then I look at the internet

246:16and then the internet says, Joe Rogan slammed Sanjay

246:20like as if it was a heated debate that Joe won.

246:24And it's like, all right,

246:26it's really the temperature being brought down.

246:30Real conversation between two humans.

246:32That wasn't really a debate.

246:34It was just a conversation and that was a success.

246:38I definitely think it was a success,

246:40but I also felt that a takeaway,

246:47and again, because this is something that I don't agree with,

246:51even though I have great, as I've said, respect for Joe,

246:54I think a reasonable person listening to that conversation

246:58would come away with the conclusion

247:00that all in all these vaccines are a good thing,

247:05but if you're young and healthy, you probably don't need it.

247:11And I just felt that there was a stronger case to be made,

247:16even though Sanjay made it.

247:17It wasn't that Sanjay didn't make it.

247:19It was just that in the flow of that conversation,

247:22I felt that the case for the vaccines

247:26and the vaccines both as an individual choice

247:28and then certainly again, as I said before,

247:31I think that while people can be afraid of the vaccines,

247:34the virus itself is much scarier

247:37and we're seeing it now in real time

247:40with these variations and variants.

247:43I just felt that that was kind of the rough takeaway

247:47from that conversation.

247:50And I felt that Sanjay, again, whom I love,

247:54I felt it could have made his case a little bit stronger.

247:56So the thing he succeeded is he didn't come off

248:00as like a science expert looking down at everybody,

248:07talking down to everybody.

248:09So he succeeded in that, which is very respectful.

248:12But I also think sort of making the case

248:15for taking the vaccine when you're a young, healthy person,

248:19when you're sitting across from Joe Rogan

248:22is like a high difficulty on the video game level.

248:26For sure.

248:26So it's difficult to do.

248:30Yeah, for sure. It's difficult to do.

248:31And also it's difficult to do

248:32because it's not as simple as like, look at the data.

248:38There's a lot of data to go through here.

248:42And there's also a lot of non data stuff,

248:45like the fact that, first of all,

248:48questioning the sources of the data,

248:50the quality of the data,

248:51because it's also disappointing about COVID

248:54is that the quality of the data is not great.

248:56But also questioning all the motivations

249:00of the different parties involved,

249:02whether it's major organizations

249:04that developed the vaccine,

249:05whether it's major institutions like NIH or NIAID

249:09that are sort of communicating to us about the vaccine,

249:12whether it's the CDC and the WHO,

249:15whether it's the Biden or the Trump administration,

249:18whether it's China and all those kinds of things,

249:20you have to, that's part of the conversation here.

249:24I mean, vaccination is not just a public health tool.

249:28It's also a tool for a government

249:30to gain more control over the populace.

249:33Like, there's a lot of truth to that too.

249:36Things that have a lot of benefit

249:40can also be used as a Trojan horse

249:44to increase bureaucracy and control.

249:47But that has to be on the table for a conversation.

249:49I think it has to be on the conversation.

249:52But your parents, when they were in the Soviet Union

249:56and here in the United States,

249:57and actually it was a big collaboration

249:59between US and Soviet Union,

250:02when the polio vaccine came out,

250:04there were people all around the world

250:06who had a different life trajectory,

250:08no longer living in fear.

250:09And all of these people who were paralyzed

250:11or killed from polio, smallpox has been eradicated.

250:15It was one of the great successes in human history.

250:20And while it for sure is true that you could imagine

250:23some kind of fraudulent vaccination effort,

250:27but here I genuinely think,

250:30I mean, whatever the number, 15 million, 16 million

250:33is the economist number of dead from COVID 19,

250:37many, many, many more people would be dead

250:39but for these vaccines.

250:41And so I get that any activity

250:44that needs to be coordinated by a central government

250:47has the potential to increase bureaucracy

250:50and increase control.

250:53But there are certain things that central governments do,

250:57like the development, particularly these mRNA vaccines,

251:00which it's purely a US government victory.

251:05I mean, it was huge DARPA funding

251:08and then the National Institute for Allergy

251:11and Infectious Disease, NIH funding.

251:13I mean, this was a public private partnership throughout

251:17and that we got a working vaccine 11 months was a miracle.

251:21So I, yeah.

251:21It's not purely a victory.

251:24Again, you have to be open minded.

251:26I'm with you here playing a bit of devil's advocate,

251:30but the people who discuss any viral drugs

251:32like ivermectin and other alternatives

251:34would say that the extreme focus on the vaccine

251:39distracted us from considering other possibilities.

251:42And saying that this is purely a success

251:46is distracting from the story

251:48that there could have been other solutions.

251:50So yes, it's a huge success

251:52that the vaccine was developed so quickly

251:55and surprisingly way more effective than it was hoped for.

252:02But there could have been other solutions

252:04and they completely distracted from us from that.

252:08In fact, it distracted us from looking into a bunch of things

252:11like the lab leak.

252:12And so it's not a pure victory.

252:15And there's a lot of people that criticize

252:18the overreach of government and all of this.

252:20That one of the things that makes the United States great

252:24is the individualism and the hesitancy to ideas of mandates.

252:31Even if the mandates on mass will have a positive,

252:35even strongly positive result,

252:37many Americans will still say no.

252:43Because in the long arc of history,

252:46saying no in that moment will actually lead

252:49to a better country and a better world.

252:53So that's a messed up aspect of America,

252:57but it's also a beautiful part.

252:59We're skeptical even about good things.

253:03I agree and certainly we should all be cautious

253:08about government overreach, absolutely.

253:11And it happens in all kinds of scenarios

253:14with incarceration with a thousand things.

253:17And we also should be afraid of government underreach

253:21that if there is a problem that could be solved

253:24by governments and that's why we have governments

253:26in the first place is that there's just certain things

253:28that individuals can't do on their own.

253:31And that's why we pool our resources

253:34and we, in some ways, sacrifice our rights

253:38for this common thing.

253:39And that's why we don't have, hopefully,

253:41people, murderers marauding

253:42or people driving 200 miles down the street.

253:45We have a process for arriving at a set of common rules.

253:49And so, while I fully agree that we need to respect

253:52and we need to listen, we need to find that right balance.

253:56And you've raised the magic I word, ivermectin.

254:00And so, an ivermectin, like my view has always been,

254:06ivermectin could be effective, it could not be effective.

254:09Let's study it through a full process.

254:12And when you had Francis Collins with you,

254:14even while he was making up stories about this wrestler,

254:19he was saying, yeah, exactly.

254:22But he was saying that they're going to do

254:25a full randomized highest level trial of ivermectin.

254:28And if ivermectin works,

254:30then that's another tool in our toolbox.

254:32And I think we should.

254:34And I think that Sanjay was absolutely correct

254:37to concede the point to Joe,

254:40that it was disingenuous for people,

254:43including people on CNN,

254:45to say that ivermectin is for livestock.

254:48And so, I definitely think that we have to,

254:53like we have to have some kind of process

254:55that allows us to come together.

254:57And I totally agree that the great strength of America

255:01is that we empower individuals.

255:03It's the history of our frontier mentality in our country.

255:06So we, I 100% agree that we have to allow that,

255:11even if sometimes it creates messy processes

255:15and uncomfortable feelings and all those sorts of things.

255:19You are an ultra marathon runner.

255:22Yes.

255:23What are you running from?

§27Transcript · 4:15:27–4:24:31

255:27No.

255:28It's the right, it's the funny thing is,

255:30so I'm an ultra marathoner and I've done 13 Ironmans.

255:34And people say, oh my God, that's amazing.

255:3613 Ironmans.

255:37And what I always say, no, one Ironman is impressive.

255:4113 Ironmans, there's something effing wrong with you.

255:44We just need to figure out what it is.

255:45Yeah, there's some demons you're trying to work through.

255:48I mean, well, you're doing the work though.

255:49Most people just kind of let the demons sit in the attic.

255:53No, what have you learned about yourself,

255:57about your mind, about your body, about life,

256:00from taking your body limit in that kind of way

256:05to running those kinds of distances?

256:07Well, it's a great question.

256:08And I know that you are also kind of exploring

256:10the limits of the physical.

256:12And so for me in doing the Ironmans and the ultra marathons,

256:17it's always the same kind of lesson,

256:20which is just when you think you have nothing left,

256:25you actually have a ton left.

256:27There are a lot of resources that are there

256:31if you call on them.

256:32And the ability to call on them has to be cultivated.

256:38And so for me, especially in the Ironman,

256:42and Ironman in many ways is harder than the ultra marathons

256:45because I'll be at, I mean, it's 140 miles.

256:48I'll be at a 100 mile, 120, having done the swim

256:52and then the bike and I'll be whatever,

256:56six miles into the run.

256:58And I'll think, I feel like shit.

257:01I have nothing left.

257:02How am I possibly gonna run 20 miles more?

257:07But there's always more.

257:10And I think that for me, these extreme sports

257:15are my process of exploring what's possible.

257:21And I feel like it applies in so many different areas

257:25of life where you're kind of pushing

257:28and it feels like the limit.

257:30And one of my friend of mine,

257:33who I just have so much respect for,

257:35who actually be a great guest

257:37if you haven't already interviewed him is Charlie Angle.

257:41And Charlie, he was a drug addict.

257:44He was in prison, his life was total shit.

257:48And somehow, and I can't remember the full story,

257:50he just started running around the prison yard.

257:55And it's like Forrest Gump.

257:56And he just kept running and running.

257:59And then he got out of prison and he kept running

258:02and he started doing ultra marathons,

258:04started inspiring all these other people.

258:07Now he's written all these books.

258:09As a matter of fact, we just spoke a few months ago

258:12that he's planning on running from the Dead Sea

258:18to somehow to the top of Mount Everest,

258:20from the lowest point to the highest point on earth.

258:23And I said, well, why are you stopping there?

258:25Why don't you get whatever camera in

258:29and go down to the lowest part of the ocean,

258:32go to the lowest part of the ocean

258:34and then talk to Elon Musk or Jeff Bezos

258:38and go to the kind of the highest place

258:40than the stratosphere you can get.

258:42But it's this thing of possibility.

258:44And I just feel like so many of us and myself included,

258:49we get stuck in a sense of what we think is our range.

258:54And if we're not careful, that can become our range.

258:57And that's why for me in all of life,

259:00it's all about like we've been talking about,

259:02challenging the limits, challenging assumptions,

259:06challenging ourselves and hopefully,

259:09we do it in a way that kind of doesn't hurt anybody.

259:12When I'm at the Ironman, they have all these little kids

259:15and they'll have these little shirts

259:17and it'll say like, my dad is a hero

259:19and have the little Ironman logo.

259:21And I wanna say, it's like, no,

259:22your dad is actually a narcissistic dick

259:25who goes on eight mile bike rides every Sunday

259:29rather than spend time with you.

259:31And so we shouldn't hurt anybody.

259:34But for me, and also I just find it very enjoyable

259:38and I hope I'm not disclosing too much

259:41about our conversation before we went live

259:44where you're doing so many different things

259:46with running and your martial arts.

259:48And I encouraged you to do ultra marathons

259:53because there's so many great ones in Texas.

259:55It's actually surprisingly a very enjoyable way

259:58to spend a day.

259:59Like how would you recommend?

260:01So yeah, for people who might not know,

260:03I've never actually even run a marathon.

260:05I've run 22 miles in one time at most.

260:08I did a four by four by 48 challenge with David Goggins

260:13where you run four miles every four hours.

260:16Is it different as less to do with the distance

260:19and more to do with the sleep deprivation.

260:21What advice would you give to a first time ultra marathon

260:24or like me trying to run 50 or more miles

260:27or for anybody else interested

260:30in this kind of exploration of their range?

260:32What I always tell is the same advice is register.

260:36Pick your timeline of when you think you can be ready.

260:39Make it, depending on where you are now,

260:41make it six months, make a year,

260:43and then register for the race.

260:45And then once you're registered,

260:47just work back from there, what's it going to take?

260:49But one of the things for people who are just getting going,

260:52you really do need to make sure

260:53that your body is ready for it.

260:55And so particularly, and particularly as we get older,

260:59strengthening is really important.

261:02So I'll do a plug for my brother, Jordan Metzl.

261:06He's a doctor at hospital for special surgery,

261:08but his whole thing is functional strength.

261:10And so, and people know about,

261:12and you can actually even go to his website.

261:15You can just Google Jordan Metzl Iron Strength,

261:17but it's all about like burpees

261:19and just building your muscular strength

261:21so that you don't get injured as you increase.

261:25And then just increase your mileage with,

261:27in some steady way, make sure that you take rest days

261:31and listen to your body because people like you

261:34who are just very kind of mind over matter,

261:37like you were telling me before about you have an injury,

261:39but you kind of run a little bit differently.

261:41And we need to listen to our bodies

261:44because our bodies are communicating.

261:48But I think it was kind of little by little magic is possible.

261:53And what I will say is,

261:54and I also have done lots and lots of marathons,

261:58and I always tell people that the ultra marathons,

262:01at least the ones that I do,

262:02and I shouldn't misrepresent myself.

262:04I mean, there are people who do 500 mile races.

262:07The ones that I do are 50K mountain trail runs,

262:11which is 32 miles.

262:12So I do the kind of the easier side of ultras,

262:17but it's actually much easier than a marathon

262:19because some of the mountain ones,

262:21sometimes it's so steep that you can't,

262:25you have to walk it

262:26because walking is faster than running.

262:29And every four or five miles in the supported races,

262:32you stop and eat blintzes and foiled potatoes.

262:35It's actually quite enjoyable.

262:36But as I started to tell you before we went live,

262:42so I've done for lots of years,

262:43these 50K mountain trail runs,

262:45and I was going to Taiwan a number of years ago

262:48for something else.

262:49And I thought, well, wouldn't it be fun

262:50to do an ultra marathon in Taiwan?

262:53I looked and that the weekend after my visit,

262:56there was a marathon.

262:57It was called the,

262:59every ultra marathon, it was called the Taiwan Beast.

263:01And I figured, oh, beasts, what are they talking about?

263:03It's 50K mountain trail,

263:05and I've done a million of them.

263:06And then I went to register.

263:07And then as part of registration,

263:09they said, you need to have all of this equipment.

263:11And it was all this like wilderness survival equipment.

263:14And I was thinking, God, these Taiwanese,

263:17but what a bunch of wimps.

263:18You have to carry, give me a break, 50K mountain trail.

263:22So I get there and the race starts

263:24at like 4.30 in the morning in the middle of nowhere.

263:27And you have to wear headlamps

263:28and everyone's carrying all this stuff.

263:29And you kind of go running out into the rainforest.

263:34It was the hardest thing I've ever done in my,

263:36it took 19 hours.

263:38There were maybe 15 cliff faces, like a real cliff.

263:41And somebody had dangled like a little piece of string.

263:44And so you had to hold onto the string with one hand

263:46while it was in the pouring rain, climb up these cliffs.

263:49There were maybe 20 river crossings,

263:52but not just like a little stream, like a torrential river.

263:57There were some things where it was so steep

264:00that everyone was just climbing up

264:02and then you'd slide all the way down and climb up.

264:03And there were people who I met on the way out there

264:07who were saying, oh yeah,

264:07I did the Sahara 500 kilometer race.

264:11And those people were just sprawled out.

264:15A lot of them didn't finish.

264:17So that was the hardest thing I've ever.

264:19So how do you get through something like that?

264:22You just, one step at a time?

264:23Was there, do you remember, is there a?

264:26Yeah.

264:27Is there a dark moments

264:28or is it kind of all spread out thinly?

§28Transcript · 4:24:31–4:33:07

264:31It wasn't really dark moments.

264:34I mean, there was one thing where I'd been running so long

264:36I thought, well, I must almost be done.

264:39And then I found out I had like 15 miles more.

264:44But I guess with all of these things,

264:48it's the messages that we tell ourselves.

264:51And so for me, it's like the message I always tell myself

264:55is quitting isn't an option.

264:58I mean, once in a while you kind of have to quit

265:00if like, listen to the universe,

265:02if whatever, you're gonna kill yourself or something.

265:04But for me, it was just, whatever it takes,

265:08there's no way I'm stopping.

265:10And if I have to go up this muddy hill 20 times

265:14because I keep sliding, I'm sure there's a way.

265:17It's probably a personality flaw.

265:21Where does your love for chocolate come from?

265:23Oh, it's a great question.

265:24And in both of my Joe Rogan interviews,

265:27that's the first question that he asked.

265:29So I'm glad that we've gotten to that.

265:30So one, I've always loved chocolate.

265:33And I call it like a secret, but now that I keep telling,

265:37if you keep telling the same secret,

265:39it's actually no longer a secret,

265:42that I have a secret, which is not secret

265:45because I'm telling you on a podcast,

265:47life as a chocolate shaman.

265:50And so when I give keynotes at tech conferences,

265:53I always say, I'm happy to give a keynote,

265:55but I want to lead a sacred cacao ceremony in the night.

265:59I'm actually, believe it or not,

266:00the official chocolate shaman

266:02of what used to be called exponential medicine,

266:05which is part of Singularity University.

266:06Now, my friend Daniel Kraft who runs it,

266:09it's going to be called NextMed.

266:12And so, but I'll have to go back.

266:14As I was going to Berlin a lot of years ago,

266:19and I've always loved chocolate,

266:20I was going to Berlin to give a keynote

266:23at a big conference called TOA, Tech Open Air.

266:28And so when I got there, the first night,

266:31I was supposed to give a talk,

266:33but there had been some mix up.

266:34They'd forgotten to reserve the room.

266:36And so the talk got canceled.

266:38And in the brochure, they had all these different events

266:41around Berlin that you could go to.

266:44And one of them was a cacao ceremony.

266:46And so I went there and actually met somebody,

266:49Viviana, who is still a friend,

266:52but I met, going in there,

266:53and there was this cacao ceremony.

266:54These kind of hippie dudes.

266:56And then everybody got the cacao.

266:59And then they said, all right,

267:01as they talked a little bit about the process,

267:03and then they said, all right,

267:04everyone just stand and kind of,

267:06we're going to spin around in a circle for 45 minutes.

267:09And so I spun around in the circle for like 10 minutes,

267:12but then I had to leave

267:14because I had to go to something else.

267:15And so that, I thought that was that.

267:18But then I saw Viviana the next day,

267:21and I said, well, how did the cacao ceremony go?

267:23And she showed me these pictures

267:25of all of these people, mostly naked,

267:28like it turned into chaos.

267:30Oh, that's awesome.

267:31And it was like, oh, and so let me get this straight.

267:33People drank chocolate,

267:35then they spun around in a circle,

267:37and something else happened.

267:39And anyway, so then two days later,

267:41I was invited to another cacao ceremony,

267:43which was also actually part of this Toa.

267:46And that was kind of more structured,

267:48and it was more sane because it was part of this thing.

267:51And at the end of that, I had this,

267:53I thought one, the greatest thing ever,

267:56a sacred cacao ceremony,

267:58like you drink chocolate milk and everybody's free.

268:01And I love that idea because I've never done drugs,

268:05I don't drink.

268:07But just part of it is because I think whatever,

268:09like I was saying with the ultra running,

268:12all of the possibilities are within us

268:14if we can get out of our own way.

268:16And then I thought, well, you know,

268:17I think I can do a better job

268:20than what I experienced in Berlin.

268:22So I came back and I thought, all right,

268:23I'm gonna get accredited as a cacao shaman.

268:26And this will shock you.

268:27Because I know if you're gonna be like a rabbi

268:30or a priest or something, there's some process.

268:32But shockingly, there's no official process

268:35to become a chocolate shaman.

268:38And so I thought, all right, well, you know,

268:40I'm just gonna train myself.

268:42And when I'm ready, I'm gonna declare my chocolate shamanism.

268:45So I started studying different things.

268:47And when I was ready, I just said,

268:50now I'm a chocolate shaman, self declared.

268:52Self declared.

268:53And so, but I do these ceremonies

268:55and I've done them at tech conferences.

268:58I did one in Soho House in New York.

269:01I've done it at a place Rancho La Puerta in Mexico.

269:04And every time it's the same thing.

269:05Because it just, if people are given a license to be free,

269:10just to, it doesn't matter, and what I always say is,

269:13you're here for a sacred cacao ceremony,

269:15but the truth is there's no such thing as sacred cacao.

269:18And there's no sacred mountains

269:19and there's no sacred people and there's no sacred plants.

269:22Because nothing is sacred if we don't attribute,

269:25ascribe sacredness to it.

269:28But if we recognize that everything is sacred,

269:32then we'll live different lives.

269:33And for the purpose of this ceremony,

269:36we're just gonna say, all right,

269:37we're gonna focus on this cacao,

269:39which actually has been used ceremonially for 5,000 years.

269:43It has all these wonderful properties.

269:47But it's just people who get that license

269:49and then they're just free and people are dancing

269:52and all sorts of things.

269:53Is the goal to celebrate life in general?

269:57Is it to celebrate the senses, like taste?

270:00Is it to celebrate yourself, each other?

270:03What is there?

270:04I think the core is gratitude and just appreciation.

270:09All the experiences in life?

270:10Yeah, just of being alive,

270:12of just living in this sacred world

270:15where we have all these things

270:16that we don't even pay any attention to.

270:19My friend, A.J. Jacobs, he had a wonderful book

270:23that I use the spirit of it in the ceremonies,

270:27not the exactly, but he was in a restaurant in New York,

270:31a coffee shop, and his child said,

270:33hey, where does the coffee come from?

270:35And he's like a wonderful big thinker.

270:38And he started really answering that question.

270:41Well, here's where the beans come from,

270:42but how did the beans get here

270:44and who painted the yellow line on the street

270:46so the truck didn't crash and who made the cup?

270:50And he spent a year making a full spreadsheet

270:53of all of the people who in one way or another

270:56played some role in that one cup of coffee.

271:00And he traveled all around the world thanking them.

271:03Like, it's like, thank you for painting

271:05the yellow line on the road.

271:06And so for me with the cacao, part of when I do

271:09these ceremonies is just to say like,

271:12you're drinking this cacao, but there's a person

271:15who planted the seed, there's a person

271:16who watered the plant, there's a person,

271:19and I just think that level of awareness,

271:22and it's true with anything.

271:24Like you have in front of you a stuffed hedgehog, so.

271:27Somebody made that.

271:28I love it, it's great.

271:30But like, if we just said, all right,

271:32where does this stuffed hedgehog come from?

271:35We would have a full story of globalization,

271:38of the interconnection of people all around the world

271:42doing all sorts of things of human imagination.

271:45It's beyond our capacity and our daily,

271:47we'd go insane if every day,

271:49like we're speaking into a microphone,

271:51well, what are the hundreds of years of technology

271:54that make this possible?

271:56But if just once in a while, we just focus on one thing

271:59and say, this thing is sacred.

272:01And because I'm recognizing that

272:04and I'm having an appreciation for the world around me,

272:07it just kind of makes my life feel more sacred.

272:10It makes me recognize my connection to others.

272:12So that's the gist of it.

272:14Yeah, it's funny, I often look at

272:19things in this world and moments and just am in awe

272:24of the full

272:27universe that brought that to be.

272:33In a similar way as you're saying,

272:35but I don't as often think about exactly what you're saying,

272:38which is the number of people behind every little thing

272:41we get to enjoy.

272:43I mean, yeah, this hedgehog, this microphone,

272:46like directly, like thousands of people involved.

272:49Millions.

272:50And then indirectly, it's millions.

272:52Like, and they're all like this microphone

272:59that there's like artists, essentially,

273:01like people who made it their life's work,

273:04all the costs, like from the factories to the manufacturer,

§29Transcript · 4:33:07–4:42:20

273:07there's families that the production of this microphone

273:11and this hedgehog are fed because of the skill

273:14of this human that helped contribute to that development.

273:18Yeah, it's.

273:20And like Isaac Newton and John von Neumann

273:22are in this microphone.

273:24They're standing on the shoulders of giants

273:26and we're standing on their shoulders.

273:28And somebody will be standing on ours.

273:34You mentioned One Shared World, what is it?

273:40Well, thanks for asking.

273:41And by the way, what I will say is the people

273:42who are listening, this is so incredible

273:46and I'm so thrilled to have this kind of long conversation.

273:49Hello, person who's listening past the five hour mark.

273:54Thanks, mom.

273:56I salute you.

273:58Somebody was like sleeping for the first four hours

274:00and just woke up.

274:01Now's the good stuff, I've been saving it.

274:04But, and I have to say that so much of our lives

274:09is forced into these short bursts

274:11that I'm just so appreciative to have the chance

274:14to have this conversation.

274:15So thank you for that.

274:16Some people would say five hours is short, so.

274:18You know, let's go.

274:20And yeah, that's what my girlfriend says.

274:25Like if I was like captured and tortured

274:29and they were gonna interrogate me,

274:30it's like at the end they'd say, all right.

274:32No, we're sick of this guy, we quit.

274:35Let him go.

274:36I love it.

274:37So background on One Shared World.

274:39I mentioned I'm on a faculty for Singularity University.

274:43In the earliest days of the pandemic,

274:45I was invited to give a talk on whether the tools

274:48of the genetics and biotech revolutions

274:50were a match for the outbreak.

274:52And my view was then as now

274:55that the answer to that question is yes.

274:57But I woke up that morning

274:58and I felt that that wasn't the most important talk

275:02that I could give.

275:03There was something else that was more pressing for me.

275:06And that was the realization,

275:08they were asking the question,

275:09well, why weren't we prepared for this pandemic?

275:12Because we could have been, we weren't.

275:14And why can't, and because of that,

275:17why can't we respond adequately to this outbreak?

275:23And then there was the thing, well,

275:24if we, even if we respond somehow miraculously

275:27overcome this pandemic, it's a pyrrhic victory

275:31if we don't prepare ourselves to respond

275:35to the broader category of pandemics,

275:37particularly as we enter the age of synthetic biology.

275:40But if somehow miraculously we solve that problem,

275:44but we don't solve the problem of climate change,

275:47well, kind of who cares?

275:48We didn't have a pandemic,

275:49but we wiped everybody out from climate change.

275:51And let's just say, you get where this is going,

275:55that we organize ourselves and we solve climate change.

275:58And then we have a nuclear war

276:00because everybody's, particularly China now,

276:03but US, the former Soviet Union

276:05are building all these nuclear weapons.

276:07Who cares that we solved climate change

276:09because we're all gone anyway.

276:10And the meta category, bringing all of those things together

276:14was this mismatch between the increasingly global

276:19and shared nature of the biggest challenges that we face

276:24and our inability to solve that entire category of problems.

276:29And there's a historical issue,

276:32which is that prior to the 30 Years War in the 17th century,

276:36we had all these different kinds of sovereignty

276:38and religious and different kinds

276:41of organizational principles and everybody got in this war.

276:44And in this series of treaties

276:46that together are called the Peace of Westphalia,

276:50the framework for the modern,

276:52what we now understand as the modern nation state was laid.

276:55And then through colonialism and other means

276:58that idea of a state is what it is today,

277:03spread throughout the world.

277:05Then through particularly the late 19th

277:09and early 20th century,

277:10we realized how unstable that system was

277:14because you always had these jockeying

277:16between sovereign states and some were rising

277:18and some were falling and you ended up in war.

277:21And that was the genius of the generations

277:23who came together in 1945 in San Francisco

277:25and the planning had even started before then,

277:28who said, well, we can't just have that world,

277:30we need to have an overlay.

277:32And we talked about the UN and the WHO

277:34of systems which transcend our national sovereignties.

277:39They don't get rid of them, but they transcend them

277:42so we can solve this category of problems.

277:44But we're now reaching a point where our reach as humans,

277:47even individually, but collectively is so great

277:51that there's a mismatch between, as I said,

277:52the nature of the problems

277:53and the ability to solve those problems.

277:57And unless we can address

278:00that broader global collective action problem,

278:03we're going to extinct ourselves.

278:05And we see these different, what I call verticals,

278:08whether it's climate change

278:09or trying to prevent a nuclear weapons proliferation

278:13or anything else, but none of those can succeed.

278:16And frankly, it doesn't even matter if one succeeds

278:18because all of them have the potential

278:21to lead to extinction level events.

278:25So I gave that talk and that talk went viral.

278:30I stayed up all night the next night and I drafted,

278:32I think it was like an insanity,

278:35but I think a lot of us were manic

278:36in those early days of the pandemics

278:38wanting to do something.

278:40And so I stayed up all night and I drafted

278:42what I called a declaration of global interdependence.

278:45And I posted that on my website, my jamiemuscle.com.

278:48It's still there.

278:49And that went viral.

278:51And so then I called a meeting just on the people

278:54on my personal email list.

278:56And so we had people from 25 countries.

278:59There were all of these people

279:00who were having the same thing.

279:02There's something wrong in the world.

279:03They wanted to be part of a process of fixing it.

279:07And so it was a crazy 35 days

279:10where we broke into eight different working groups.

279:12We had an amazing team that helped redraft

279:16what became the declaration of interdependence,

279:18which is now in 20 languages.

279:21We laid out a work plan.

279:23We founded this organization called One Shared World.

279:27The URL is oneshared.world.

279:28And it's just been this incredible journey.

279:31We now have people who are participating

279:33in one way or another from 120 different countries.

279:36We have our public events exploring these issues,

279:40get millions of viewers.

279:43We have world leaders who are participating.

279:46So the vision is to work on some of these big problems,

279:51arbitrary number of problems that present themselves

279:53in the world that face all of human civilization

279:56and to be able to work together.

279:58Well, that is, but there's a macro, a meta problem,

280:02which is the global collective action problem.

280:04And so the idea is even if we just focus on the verticals,

280:10on the manifestations of the global collective action

280:12problem, there'll be an infinite number of those things.

280:16So while we work on those things,

280:18like climate change, pandemics, WMD and other things,

280:22we also have to ask the bigger questions

280:25of why can't we solve this category of problems.

280:27And the idea is, at least from my observation,

280:30is that whenever big decisions are being made,

280:34our national leaders and corporate leaders

280:37are doing exactly what we've hired them to do.

280:40They're maximizing for national interest,

280:43even, or corporate interests,

280:45even at the expense of everybody.

280:48And so it's not that we wanna get rid of states.

280:50States are essential in our world system.

280:52It's not we wanna undermine the UN,

280:54which is also essential, but massively underperforming.

280:57What we wanna do is to create

280:59an empowered global constituency of people

281:02who are demanding that their leaders at all levels

281:06just do a better job of balancing

281:09broader and narrower interests.

281:10I see.

281:11So this is more like a,

281:14make it more symmetric in terms of power.

281:17It's holding accountable the nations, the leaders.

281:22The leaders.

281:23The problem is nations are powerful.

281:26We talked about China quite a bit.

281:29How do you have an organizations of citizens of Earth

281:33that can solve this collective problem

281:36that holds China accountable?

281:39It's difficult, because UN,

281:41you could say a lot of things,

281:42but to call it effective is hard.

281:45You know, the internet almost is a kind of representation

281:50of a collective force that holds nations accountable.

281:57Not to give Twitter too much credit,

281:58but social networks, broadly speaking.

282:03So you have hope that it's possible

282:05to build such collections of humans that resist China.

282:10Not necessarily resist China,

282:12but human, I mean, our cultures change over time.

282:16I mean, the idea of the modern nation state

§30Transcript · 4:42:20–4:52:06

282:20would not have made sense to people

282:22in the 13th or 14th century.

282:24The idea that became the United Nations.

282:28I mean, it had its earliest days in the philosophies of Kant.

282:33It took a long time for these ideas to be realized.

282:39And so the idea, and we're far from successful.

282:44I mean, we've had little minor successes,

282:46which we're very proud of.

282:47We got the G20 leaders to incorporate the language

282:51that we provided on addressing the needs

282:53of the world's most vulnerable populations

282:56into the final summit communique

282:59from the G20 summit in Riyadh.

283:01This year, we're just on the verge

283:03of having our language pat on the same issue,

283:07ensuring everyone on earth has access to safe water,

283:10basic sanitation and hygiene,

283:11and essential pandemic protection by 2030

283:14passed as part of a resolution in the United Nations

283:18General Assembly.

283:19And we're primarily, I mean, it's young people

283:22all around the world.

283:23And when I told them in the beginning of this year,

283:26this is our goal.

283:26We're gonna get the UN General Assembly

283:28to pass a resolution with our language in it.

283:32I mean, first, I think they all thought it was insane,

283:35but they were too young and inexperienced

283:38to know how insane it was.

283:39But now these young people are just so excited

283:42that it's actually happening.

283:43So what we're trying to do is really to create a movement,

283:48which we don't feel that we need to do from scratch

283:51because there are a lot of movements.

283:53Like right now, we just had the Glasgow G20,

283:56I mean, I'm sorry, the Glasgow Climate Change Cup 26,

284:00and then Greta Thunberg, who has a huge following

284:03and who is an amazing young woman,

284:05but I was kind of disappointed in what she said afterwards.

284:08It became like a meme on Twitter, which was blah, blah, blah.

284:13And basically it was like, blah, blah, blah,

284:15these old people are just screwing around

284:17and it's a waste of time.

284:18And definitely the critique is merited,

284:22but young people have never been more empowered,

284:25educated, connected than they are now.

284:29And so we've had a process with One Shared World

284:36where we partnered with the Model United Nations,

284:39the Aga Khan Foundation, the India Sanitation Coalition.

284:42And what we did is say, all right, we have this goal,

284:44water sanitation, hygiene, and pandemic protection

284:46for everyone on earth by 2030.

284:49And we had debates and consultations

284:52using the Model UN framework all around the world

284:54in multiple languages.

284:56And we said, come up with a plan

284:58for how this could be achieved.

284:59And these brilliant young people in every country,

285:02not every country, most countries,

285:04they all contributed, then we had a plan.

285:06Then I recruited friends of mine,

285:08like my friend Hans Carrell in Sweden,

285:11who's the former chief counsel of the whole United Nations,

285:14and asked him and others to work with these young people

285:18and representatives to turn that

285:20into what looks exactly like a UN resolution.

285:24It's just written by a bunch of kids all around the world.

285:28We then sent that to every permanent representative,

285:31every government representative at the UN.

285:34And that was why working

285:35with the German and Spanish governments,

285:37why the language is centralized from that document

285:40is about to pass the UN.

285:41And it doesn't mean that just passing

285:43a UN General Assembly resolution changes anything,

285:46but we think that there's a model of engaging people,

285:49just like you're talking about,

285:50these people who are outside

285:53of the traditional power structures

285:55and who want to have a voice.

285:57But I think we need to give a little bit of structure

286:00because just going, I'm a big fan of Global Citizen,

286:03but just going to a Global Citizen concert

286:06and waving your iPhone back and forth

286:09and tweeting about it isn't enough

286:11to drive the kind of change that's required.

286:14We need to come together, even in untraditional ways,

286:17and articulate the change we want

286:20and build popular movements to make that happen.

286:22And popular means scale and movements at scale

286:26that actually, at the individual level, do something

286:30and that's then magnified with the scale

286:33to actually have significant impact.

286:35I mean, at its best, you hear a lot of folks talk

286:39about the various cryptocurrencies as possibly helping.

286:44You have young people get involved

286:46in challenging the power structures

286:49by challenging the monetary system.

286:51And there's, some of it is number go up,

286:56people get excited when they can make a little bit of money,

287:00but that's actually almost like an entry point

287:04because then you almost feel empowered.

287:07And because of that, you start to think

287:10about some of these philosophical ideas

287:11that I, as a young person, have the power

287:15to change the world.

287:16All of these senior folks in the position of power,

287:20they were, first of all, they were once young

287:24and powerless like me.

287:26And I could be part of the next generation

287:29that makes a change.

287:30Well, all the things I see that are wrong

287:32with the world, I can make it better.

287:34And it's very true that the overly powerful nations

287:39of the world could be a relic of the past.

287:43That could be a 20th century and before idea

287:47that was tried, created a lot of benefit,

287:52but we also saw the problems with that kind of world,

287:56extreme nationalism.

287:58We see the benefits and the problems of the Cold War.

288:02Arguably Cold War got us to the moon,

288:06but there could be other, a lot of other different

288:08mechanisms that inspired competition,

288:11especially friendly competition between nations

288:13versus adversarial competition that resulted

288:16in the response to COVID, for example,

288:18with China and the United States and Russia

288:20and the secrecy, the censorship.

288:25Yeah, and all the things that are basically

288:27against the spirit of science

288:31and resulted in the loss of trillions of dollars

288:34and the cost of countless lives.

288:37What gives you hope about the future, Jamie?

288:41Well, one of the things, you mentioned cryptocurrency

288:45and then as you know better than most,

288:47there's cryptocurrency and then underneath

288:50the cryptocurrency, there's the blockchain

288:52and the distributed ledger.

288:54And then like we talked about, there are all these

288:56young people who are able to connect with each other,

289:00to organize in new ways.

289:03And I work with these young people every single day

289:07through One Shared World primarily,

289:09but also other things.

289:11And there's so much optimism.

289:13There's so much hope that I just have a lot of faith

289:18that we're gonna figure something out.

289:20I'm an optimist by nature.

289:23And that doesn't mean that we need to be blind

289:26to the dangers.

289:27There are very, very real dangers,

289:30but just given half the chance, people wanna be good.

289:34People want to do the right thing.

289:37And I do believe that there's a role,

289:40maybe there's a role for the at least near term

289:42for governments, but there's always a role for leadership.

289:46And I'm, I guess like a Gramscian in the sense

289:50that I think that we need to create frameworks

289:53and structures that allow leaders to emerge.

289:58And we need to build norms so that the leaders who emerge

290:02are leaders who call on us, inspire our best instincts

290:08and not drive us toward our worst.

290:10But I really see a lot of hope.

290:13And when you say this all the time in your podcast,

290:19and you may even be more optimistic to me

290:21as you look at the darkest moments of human history

290:24and see hope, but we're kind of a crazy, wonderful species.

290:29I mean, yes, we figured out ways to slaughter each other

290:32at scale, but we've come up with these wonderful philosophies

290:36about love and all of those things.

290:38And yeah, maybe the Bonobos have some love

290:41in their cultures, but this,

290:43we're kind of a wonderful magical species.

290:46And if we just can create enough of an infrastructure,

290:49doesn't need to be and shouldn't be controlling,

290:52just enough of an infrastructure

290:54so that people are stakeholders,

290:56feel like they're stakeholders

290:57in contributing to a positive story,

291:00I just really feel the sky is the limit.

291:04So if there's somebody who's young right now,

291:06somebody in high school, somebody in college

291:08listening to you, you've done a lot of incredible things.

291:12You're respected by a lot of the elites.

291:17You're respected by the people.

291:20So you're both able to sort of speak to all groups,

291:26walk through the fire, like you mentioned

291:29with the slab leak.

291:32What advice would you give to young kids today

291:36that are inspired by your story?

291:38Well, thank you.

291:39I mean, I think there's one, there's lots of,

291:41I'm honored if anybody is inspired,

291:44but it's the same thing as I said with the science

291:48that it's all about values.

291:50The core of everything is knowing who you are.

291:54And so yes, I mean, there's the broader thing

291:56of follow your passions, a creative mind

292:01and an inquisitive mind is the core of everything

292:03because the knowledge base is constantly sharing.

§31Transcript · 4:52:06–4:55:09

292:06So learning how to learn,

292:09but at the core of everything is investing

292:13in knowing who you are and what you stand for.

292:16Because that's the way, that's the path

292:21to leading a meaningful life, to contributing,

292:24to not feeling alienated from your life as you get older.

292:28And just like you live, it's an ongoing process

292:34and we all make mistakes

292:35and we all kind of travel down wrong paths

292:38and just have some love for yourself

292:41and recognize that just at every,

292:44like I was saying with the Ironman,

292:46just when you think there's no possibility

292:50that you can go on, there's a 100% possibility

292:54that you can go on.

292:55And just when you think that nothing better

292:58will happen to you, there's a 100% chance

293:02that something better will happen to you.

293:03You just gotta keep going.

293:05Jamie, I've been a fan of yours.

293:08I think first heard you on Joe Rogan Experience,

293:11but I've been following your work,

293:13your bold, fearless work with speaking about the lab leak

293:18and everything you represent

293:20from your brilliance to your kindness.

293:23And the fact that you spent your valuable time with me today

293:27and now I officially made you miss your flight.

293:31And the fact that you said that

293:34whether you were being nice or not,

293:35I don't know that you will be okay with that

293:38means the world to me.

293:39And I'm really honored that you spent your time with me today.

293:42Well, really, it's been such a great pleasure

293:44and thank you for creating a forum

293:48to have these kinds of long conversations.

293:51So I really enjoyed it and thank you.

293:53And if anybody has now listened for,

293:58what's it been, five and a half hours?

293:59Yep.

294:00Thank you for listening.

294:01Welcome to Five Hour Club.

294:03Represent.

294:04Exactly.

294:06Thank you, Jamie.

294:07Thanks, Lex.

294:09Thanks for listening to this conversation

294:10with Jamie Metzl.

294:11To support this podcast,

294:13please check out our sponsors in the description.

294:16And now let me leave you some words from Richard Feynman

294:19about science and religion,

294:21which I think also applies to science and geopolitics

294:24because I believe scientists have the responsibility

294:27to think broadly about the world

294:29so that they may understand the bigger impact

294:31of their inventions.

294:33The quote goes like this,

294:34In this age of specialization,

294:37men who thoroughly know one field

294:39are often incompetent to discuss another.

294:42The old problems,

294:44such as the relation of science and religion,

294:46are still with us

294:47and I believe present as difficult dilemmas as ever,

294:51but they are not often publicly discussed

294:54because of the limitations of specialization.

294:57Thank you for listening and hope to see you next time.

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