肠道感知与肠脑轴的科学 | Diego Bohórquez 博士

这 section of the episode develops the topic 通过 the following source points: Please note 那 这 transcript is not in its final form 和 会 be edited. Welcome to the Huberman Lab 播客 where 我们 discuss science 和 science-based tools 对于 everyday life. I'm Andrew Huberman 和 I'm a professor of 神经生物学 和 ophthalmology at Stanford School of Medicine. My guest today is Dr. Diego Borque. Dr. Diego Borque is a professor of medicine 和 神经生物学 at Duke University. He did his 训练 in gastrointestinal physiology 和 nutrition 和 later neuroscience, 和 by combining 那 unique 训练 和 expertise, he's considered a pioneer 和 leader in so-called gut sensing 或 the gut 大脑 axis. Now, when most 人们 hear the words gut-大脑 axis, they immediately think of the so-called microbiome, which is extremely 重要, 但 那 is not the topic of Dr. Borque expertise. Dr. Borque focuses on the actual sensing 那 occurs within 一's gut, just as 一 会 sense light 与 their eyes 或 sound waves 与 their ears 对于 hearing. 我们的 gut contains 受体 那 respond to 具体的 components of food, including amino acids, fats, sugars, 和 other aspects of food including 温度, acidity, 和 other micronutrients 那 are contained in food 那 give 我们的 gut the clear picture of what is happening at the 水平 of the types 和 qualities of food 那 我们 ingest, 和 then communicate 那 below 我们的 conscious detection to 我们的 大脑 in order to drive 具体的 patterns of thinking, emotion 和 behavior. 和 of course, everybody has heard of 我们的 so-called gut sense 或 我们的 ability to believe 或 feel certain things based on perceptions 那 are below 或 somehow 不同的 从 conventional language. Today, Dr. Borque teaches us 关于 all aspects of gut sensing, how it occurs at the 水平 of 具体的 neurons 和 neural 回路, how the 大脑 responds to 那, how 具体的 foods 和 components of food impact not just 我们的 feeling of digestion 或 feeling good 或 bad 关于 what 我们 ate, 但 indeed how 我们 feel overall, how safe 我们 feel, how excited 我们 feel, whether 或 not 我们 feel depressed 或 sad, angry, 或 happy. Today's discussion, I promise 你, is unique among all discussions of neuroscience, at least 那 I've heard previously in 那 it combines 二 seemingly disparate fields, nutrition 和 neuroscience. Indeed, today's discussion gets 进入 how 不同的 foods 和 food combinations impact how 我们 feel 和 what 我们 crave 和 what 我们 tend to avoid. 我们 also get to hear the absolutely extraordinary story of Dr. Borches upbringing in the Amazon jungle 和 how his knowledge 和 intuition 关于 plants has influenced his science 和 how the incredible science 那 his laboratory is doing relates to all of us 和 我们的 ability to better tap 进入 我们的 gut sense. 之前 我们 begin, I'd like to emphasize 那 这 podcast is separate 从 my teaching 和 研究 walls at Stanford. It is 然而 part of my desire 和 effort to bring zero cost to consumer information 关于 science 和 science related tools to the general public. In keeping 与 那 theme, I'd like to thank the sponsors of today's podcast. 我们的 首先 sponsor is JoVE. JoVE makes medical grade red light therapy devices. Now, if there's 一 thing 那 I've consistently emphasized on 这 podcast, it's the incredible impact 那 light meaning photons 可以 have on 我们的 心理健康 和 身体健康. Red 和 near infrared light has been shown to have profound effects on improving cell health, which 可以 help 与 faster 肌肉 恢复, boosting healthier 皮肤, 减少 pain 和 炎症, 增强 sleep, 和 much 更多. What sets Juve apart is 那 it uses clinically effective wavelengths, emits a safe 和 effective dose of red 和 near infrared light, 和 most importantly, offers the only true medical grade red light panel available. I personally try to use the handheld juve Go unit as it's called every 天 和 尤其是 when I'm on the road traveling. If 你'd like to try JoVE, 你 可以 go to jove.com/huberman. 那's JOO vv.com/huberman. JoVE is offering an exclusive discount to Huberman Lab 播客 listeners 与 up to $400 off jev products. Again, 那's jo.com/huberman. Today's episode is also brought to us by element. Element is an electrolyte drink 那 has everything 你 need. 那 means the electrolytes, sodium, magnesium, 和 potassium in the correct amounts 和 ratios 和 nothing 你 don't, which means no sugar.